Matches in SemOpenAlex for { <https://semopenalex.org/work/W3082643463> ?p ?o ?g. }
- W3082643463 endingPage "1" @default.
- W3082643463 startingPage "1" @default.
- W3082643463 abstract "Non‑alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases and can lead to liver cirrhosis or liver cancer in severe cases. In recent years, the incidence of NAFLD has increased substantially. The trend has continued to increase and has become a key point of concern for health systems. NAFLD is often associated with metabolic abnormalities caused by increased visceral obesity, including insulin resistance, diabetes mellitus, hypertension, dyslipidemia, atherosclerosis and systemic microinflammation. Therefore, the pathophysiological mechanisms of NAFLD must be clarified to develop new drug treatment strategies. Recently, researchers have conducted numerous studies on the pathogenesis of NAFLD and have identified various important regulatory factors and potential molecular mechanisms, providing new targets and a theoretical basis for the treatment of NAFLD. However, the pathogenesis of NAFLD is extremely complex and involves the interrelationship and influence of multiple organs and systems. Therefore, the condition must be explored further. In the present review, the abnormal metabolic process, including glucose, lipid, amino acid, bile acid and iron metabolism are reviewed. It was concluded that NAFLD is associated with an imbalanced metabolic network that involves glucose, lipids, amino acids, bile acids and iron, and lipid metabolism is the core metabolic process. The current study aimed to provide evidence and hypotheses for research and clinical treatment of NAFLD." @default.
- W3082643463 created "2020-09-08" @default.
- W3082643463 creator A5004144561 @default.
- W3082643463 creator A5036448279 @default.
- W3082643463 creator A5056298255 @default.
- W3082643463 creator A5077695586 @default.
- W3082643463 date "2020-08-28" @default.
- W3082643463 modified "2023-10-11" @default.
- W3082643463 title "Abnormal metabolic processes involved in the pathogenesis of non‑alcoholic fatty liver disease (Review)" @default.
- W3082643463 cites W11793393 @default.
- W3082643463 cites W1638384149 @default.
- W3082643463 cites W1768557696 @default.
- W3082643463 cites W1852430852 @default.
- W3082643463 cites W1856151485 @default.
- W3082643463 cites W1863223166 @default.
- W3082643463 cites W1897974851 @default.
- W3082643463 cites W1911950143 @default.
- W3082643463 cites W1925788292 @default.
- W3082643463 cites W1964064151 @default.
- W3082643463 cites W1964572117 @default.
- W3082643463 cites W1972416270 @default.
- W3082643463 cites W1984393514 @default.
- W3082643463 cites W1992969398 @default.
- W3082643463 cites W1995765014 @default.
- W3082643463 cites W2001940599 @default.
- W3082643463 cites W2003066185 @default.
- W3082643463 cites W2003601851 @default.
- W3082643463 cites W2005558543 @default.
- W3082643463 cites W2007407160 @default.
- W3082643463 cites W2014426486 @default.
- W3082643463 cites W2014534600 @default.
- W3082643463 cites W2016650607 @default.
- W3082643463 cites W2017511982 @default.
- W3082643463 cites W2017948134 @default.
- W3082643463 cites W2020799782 @default.
- W3082643463 cites W2026583125 @default.
- W3082643463 cites W2027620179 @default.
- W3082643463 cites W2034520071 @default.
- W3082643463 cites W2038681065 @default.
- W3082643463 cites W2039827979 @default.
- W3082643463 cites W2045272381 @default.
- W3082643463 cites W2048008333 @default.
- W3082643463 cites W2056737488 @default.
- W3082643463 cites W2057896729 @default.
- W3082643463 cites W2058624808 @default.
- W3082643463 cites W2071030431 @default.
- W3082643463 cites W2071766794 @default.
- W3082643463 cites W2071991978 @default.
- W3082643463 cites W2072362233 @default.
- W3082643463 cites W2072822958 @default.
- W3082643463 cites W2073693178 @default.
- W3082643463 cites W2075517988 @default.
- W3082643463 cites W2078599166 @default.
- W3082643463 cites W2078784135 @default.
- W3082643463 cites W2079902915 @default.
- W3082643463 cites W2081112865 @default.
- W3082643463 cites W2095075233 @default.
- W3082643463 cites W2096903176 @default.
- W3082643463 cites W2097673296 @default.
- W3082643463 cites W2098906667 @default.
- W3082643463 cites W2104569290 @default.
- W3082643463 cites W2106061083 @default.
- W3082643463 cites W2108669805 @default.
- W3082643463 cites W2123083626 @default.
- W3082643463 cites W2125148955 @default.
- W3082643463 cites W2125378602 @default.
- W3082643463 cites W2130375490 @default.
- W3082643463 cites W2131283756 @default.
- W3082643463 cites W2134823147 @default.
- W3082643463 cites W2136769963 @default.
- W3082643463 cites W2137299052 @default.
- W3082643463 cites W2143296415 @default.
- W3082643463 cites W2145888094 @default.
- W3082643463 cites W2148258053 @default.
- W3082643463 cites W2149852822 @default.
- W3082643463 cites W2150961941 @default.
- W3082643463 cites W2152352364 @default.
- W3082643463 cites W2163065789 @default.
- W3082643463 cites W2164389437 @default.
- W3082643463 cites W2164556013 @default.
- W3082643463 cites W2167919759 @default.
- W3082643463 cites W2172084645 @default.
- W3082643463 cites W2176139361 @default.
- W3082643463 cites W2176783202 @default.
- W3082643463 cites W2189784675 @default.
- W3082643463 cites W2204688218 @default.
- W3082643463 cites W2230400342 @default.
- W3082643463 cites W2239895553 @default.
- W3082643463 cites W2265176083 @default.
- W3082643463 cites W2267342248 @default.
- W3082643463 cites W2267899659 @default.
- W3082643463 cites W2281525612 @default.
- W3082643463 cites W2285354736 @default.
- W3082643463 cites W2296386264 @default.
- W3082643463 cites W2304817904 @default.
- W3082643463 cites W2314791836 @default.
- W3082643463 cites W2321394973 @default.
- W3082643463 cites W2336168218 @default.