Matches in SemOpenAlex for { <https://semopenalex.org/work/W3082829282> ?p ?o ?g. }
- W3082829282 abstract "Abstract A new etiological model is proposed for schizophrenia that combines variability‐enhancing nonspecific factors acting during development with more specific risk factors. This model is better suited than the current etiological models of schizophrenia, based on the risk factors paradigm, for predicting and/or explaining several important findings about schizophrenia: high co‐morbidity rates, low specificity of many risk factors, and persistence in the population of the associated genetic polymorphisms. Compared with similar models, e.g., de‐canalization, common psychopathology factor, sexual‐selection, or differential sensitivity to the environment, this proposal is more general and integrative. Recently developed research methods have proven the existence of genetic and environmental factors that enhance developmental variability. Applying such methods to newly collected or already available data can allow for testing the hypotheses upon which this model is built. If validated, this model may change the understanding of the etiology of schizophrenia, the research models, and preventionbrk paradigms." @default.
- W3082829282 created "2020-09-08" @default.
- W3082829282 creator A5006266874 @default.
- W3082829282 creator A5041857600 @default.
- W3082829282 creator A5055979327 @default.
- W3082829282 creator A5057841284 @default.
- W3082829282 creator A5078615174 @default.
- W3082829282 date "2020-08-31" @default.
- W3082829282 modified "2023-10-01" @default.
- W3082829282 title "Schizophrenia: Developmental Variability Interacts with Risk Factors to Cause the Disorder" @default.
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