FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3082943863> ?p ?o ?g. }

• W3082943863 endingPage "e4350" @default.
• W3082943863 startingPage "e4337" @default.
• W3082943863 abstract "A comprehensive characterization of racial/ethnic variations in vitamin D metabolism markers may improve our understanding of differences in bone and mineral homeostasis and the risk of vitamin D-related diseases.Describe racial/ethnic differences in vitamin D metabolism markers and their associations with genetic ancestry.In a cross-sectional study within the Multi-Ethnic Study of Atherosclerosis (MESA), we compared a comprehensive panel of vitamin D metabolism markers across self-reported racial/ethnic groups of Black (N = 1759), White (N = 2507), Chinese (N = 788), and Hispanic (N = 1411). We evaluated associations of proportion African and European ancestry with this panel of markers in Black and Hispanic participants using ancestry informative markers. Latent class analysis evaluated associations between patterns of vitamin D measurements with race/ethnicity.Compared with Black participants, White participants had significantly higher serum concentrations of 25-hydroxyvitamin D and fibroblast growth factor-23; lower concentrations of parathyroid hormone and 1,25-dihydroxyvitamin D; circulating vitamin D metabolite ratios suggesting lower CYP27B1 and higher CYP24A1 activity; higher urinary concentrations of calcium and phosphorus with higher urinary fractional excretion of phosphorus; and differences in vitamin D binding globulin haplotypes. Higher percent European ancestry was associated with higher 25-hydroxyvitamin D and lower parathyroid hormone concentrations among Black and Hispanic participants. Latent classes defined by vitamin D measurements reflected these patterns and differed significantly by race/ethnicity and ancestry.Markers of vitamin D metabolism vary significantly by race/ethnicity, may serve to maintain bone and mineral homeostasis across ranges of 25-hydroxyvitamin D production, and be attributable, at least partly, to genetic ancestry." @default.
• W3082943863 created "2020-09-08" @default.
• W3082943863 creator A5002821639 @default.
• W3082943863 creator A5006040852 @default.
• W3082943863 creator A5017572190 @default.
• W3082943863 creator A5024425228 @default.
• W3082943863 creator A5025563270 @default.
• W3082943863 creator A5028606685 @default.
• W3082943863 creator A5030943960 @default.
• W3082943863 creator A5031218554 @default.
• W3082943863 creator A5032870005 @default.
• W3082943863 creator A5036283255 @default.
• W3082943863 creator A5036551563 @default.
• W3082943863 creator A5041495874 @default.
• W3082943863 creator A5042486261 @default.
• W3082943863 creator A5057163860 @default.
• W3082943863 creator A5058639364 @default.
• W3082943863 creator A5061035625 @default.
• W3082943863 date "2020-09-01" @default.
• W3082943863 modified "2023-10-17" @default.
• W3082943863 title "Race, Ancestry, and Vitamin D Metabolism: The Multi-Ethnic Study of Atherosclerosis" @default.
• W3082943863 cites W1490592890 @default.
• W3082943863 cites W1511438716 @default.
• W3082943863 cites W1858085535 @default.
• W3082943863 cites W1901809560 @default.
• W3082943863 cites W1986705224 @default.
• W3082943863 cites W1986915561 @default.
• W3082943863 cites W1991346443 @default.
• W3082943863 cites W1993862887 @default.
• W3082943863 cites W1998561594 @default.
• W3082943863 cites W2001340819 @default.
• W3082943863 cites W2003490678 @default.
• W3082943863 cites W2004426288 @default.
• W3082943863 cites W2011368668 @default.
• W3082943863 cites W2013009411 @default.
• W3082943863 cites W2015075378 @default.
• W3082943863 cites W2019530390 @default.
• W3082943863 cites W2020741906 @default.
• W3082943863 cites W2025386062 @default.
• W3082943863 cites W2031941775 @default.
• W3082943863 cites W2033866680 @default.
• W3082943863 cites W2035715328 @default.
• W3082943863 cites W2036366581 @default.
• W3082943863 cites W2036548784 @default.
• W3082943863 cites W2042639382 @default.
• W3082943863 cites W2055691650 @default.
• W3082943863 cites W2057301426 @default.
• W3082943863 cites W2062361583 @default.
• W3082943863 cites W2078066159 @default.
• W3082943863 cites W2080260619 @default.
• W3082943863 cites W2081357257 @default.
• W3082943863 cites W2082213137 @default.
• W3082943863 cites W2083333719 @default.
• W3082943863 cites W2090183661 @default.
• W3082943863 cites W2094551185 @default.
• W3082943863 cites W2098247759 @default.
• W3082943863 cites W2099716108 @default.
• W3082943863 cites W2100626233 @default.
• W3082943863 cites W2106412070 @default.
• W3082943863 cites W2107789381 @default.
• W3082943863 cites W2118311305 @default.
• W3082943863 cites W2118426146 @default.
• W3082943863 cites W2118625269 @default.
• W3082943863 cites W2142000690 @default.
• W3082943863 cites W2143098590 @default.
• W3082943863 cites W2145462912 @default.
• W3082943863 cites W2148854096 @default.
• W3082943863 cites W2154207322 @default.
• W3082943863 cites W2154271095 @default.
• W3082943863 cites W2156097706 @default.
• W3082943863 cites W2161375627 @default.
• W3082943863 cites W2161519087 @default.
• W3082943863 cites W2167944949 @default.
• W3082943863 cites W2169471788 @default.
• W3082943863 cites W2170092490 @default.
• W3082943863 cites W2171039193 @default.
• W3082943863 cites W2171942415 @default.
• W3082943863 cites W2172195613 @default.
• W3082943863 cites W2178622146 @default.
• W3082943863 cites W2255476880 @default.
• W3082943863 cites W2286368305 @default.
• W3082943863 cites W2288520313 @default.
• W3082943863 cites W2293120381 @default.
• W3082943863 cites W2330447753 @default.
• W3082943863 cites W2353663832 @default.
• W3082943863 cites W2610684611 @default.
• W3082943863 cites W2740831896 @default.
• W3082943863 cites W2748412376 @default.
• W3082943863 cites W2789599341 @default.
• W3082943863 cites W2888252253 @default.
• W3082943863 cites W2893188920 @default.
• W3082943863 cites W4213000396 @default.
• W3082943863 doi "https://doi.org/10.1210/clinem/dgaa612" @default.
• W3082943863 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7526733" @default.
• W3082943863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32869845" @default.
• W3082943863 hasPublicationYear "2020" @default.
• W3082943863 type Work @default.
• W3082943863 sameAs 3082943863 @default.

• next