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• W3083027972 startingPage "445" @default.
• W3083027972 abstract "Creating a magic bullet that can selectively kill cancer cells while sparing nearby healthy cells remains one of the most ambitious objectives in pharmacology. Nanomedicine, which relies on the use of nanotechnologies to fight disease, was envisaged to fulfill this coveted goal. Despite substantial progress, the structural complexity of therapeutic vehicles impedes their broad clinical application. Novel modular manufacturing approaches for engineering programmable drug carriers may be able to overcome some fundamental limitations of nanomedicine. We discuss how bottom-up synthetic biology principles, empowered by microfluidics, can palliate current drug carrier assembly limitations, and we demonstrate how such a magic bullet could be engineered from the bottom up to ultimately improve clinical outcomes for patients." @default.
• W3083027972 created "2020-09-11" @default.
• W3083027972 creator A5011195205 @default.
• W3083027972 creator A5013037530 @default.
• W3083027972 creator A5032609653 @default.
• W3083027972 creator A5063197356 @default.
• W3083027972 date "2021-05-01" @default.
• W3083027972 modified "2023-10-12" @default.
• W3083027972 title "Can Bottom-Up Synthetic Biology Generate Advanced Drug-Delivery Systems?" @default.
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