FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3083095246> ?p ?o ?g. }

• W3083095246 endingPage "114633" @default.
• W3083095246 startingPage "114633" @default.
• W3083095246 abstract "A new electrochemical biosensor for sensitive detection of telomerase activity based on the hybridization chain reaction and the dual interaction of the poly-adenine (polyA) DNA with Au electrode and Ce-Ti dioxide nanorods (Ce-Ti NRs) has been constructed. Deoxynucleotide triphosphates (dNTPs) can be incorporated at the 3´-OH of TS primer by telomerase to generate the extension products with telomeric repeats (TTAGGG)n (TEP), which can hybridize with hairpin (HP) DNA and open it to form a duplex DNA with a short poly-adenine DNA single-stranded tail (s1). The duplex DNA can be recognized and selectively cleaved into single-stranded DNA fragment s1 and TEP by exonuclease III (Exo III). The released TEP can then hybridize with the HP again to initiate the s1 recycling process, which will result in the massive release of s1 fragments from HP. The s1 fragments can be immobilized on the Au electrode surface through the interaction between polyA and Au electrode on one hand. On the other hand, Ce-Ti NRs can be adsorbed on the Au electrode surface by the interaction between Ce-Ti NRs and the phosphate groups of s1, resulting in the decrease of the differential pulse voltammetry (DPV) current of the redox probe. The higher activity of telomerase, more HP can be hybridized and cleaved, more poly-adenine and Ce-Ti NRs can be immobilized on electrode surface, and remarkable decrease of the DPV signal can be observed. The biosensor exhibited good sensitivity toward telomerase activity in HeLa cells." @default.
• W3083095246 created "2020-09-11" @default.
• W3083095246 creator A5004998372 @default.
• W3083095246 creator A5019686308 @default.
• W3083095246 creator A5039373148 @default.
• W3083095246 creator A5073101687 @default.
• W3083095246 date "2020-11-01" @default.
• W3083095246 modified "2023-10-15" @default.
• W3083095246 title "Electrochemical biosensor for telomerase activity assay based on HCR and dual interaction of the poly-adenine DNA with Au electrode and Ce-Ti dioxide nanorods" @default.
• W3083095246 cites W1852455217 @default.
• W3083095246 cites W1980382899 @default.
• W3083095246 cites W1985996661 @default.
• W3083095246 cites W1997685956 @default.
• W3083095246 cites W2000236047 @default.
• W3083095246 cites W2000971601 @default.
• W3083095246 cites W2010882280 @default.
• W3083095246 cites W2029932108 @default.
• W3083095246 cites W2030976397 @default.
• W3083095246 cites W2038582507 @default.
• W3083095246 cites W2041170068 @default.
• W3083095246 cites W2049188949 @default.
• W3083095246 cites W2053014859 @default.
• W3083095246 cites W2117824620 @default.
• W3083095246 cites W2179867003 @default.
• W3083095246 cites W2193515573 @default.
• W3083095246 cites W2204647341 @default.
• W3083095246 cites W2239025850 @default.
• W3083095246 cites W2278253851 @default.
• W3083095246 cites W2281261575 @default.
• W3083095246 cites W2294533988 @default.
• W3083095246 cites W2327774701 @default.
• W3083095246 cites W2523125796 @default.
• W3083095246 cites W2531549675 @default.
• W3083095246 cites W2564716811 @default.
• W3083095246 cites W2580169516 @default.
• W3083095246 cites W2766742852 @default.
• W3083095246 cites W2773198076 @default.
• W3083095246 cites W2787837034 @default.
• W3083095246 cites W2789855535 @default.
• W3083095246 cites W2943066924 @default.
• W3083095246 cites W2955764887 @default.
• W3083095246 cites W2995795878 @default.
• W3083095246 cites W3007759185 @default.
• W3083095246 cites W3011379089 @default.
• W3083095246 doi "https://doi.org/10.1016/j.jelechem.2020.114633" @default.
• W3083095246 hasPublicationYear "2020" @default.
• W3083095246 type Work @default.
• W3083095246 sameAs 3083095246 @default.
• W3083095246 citedByCount "3" @default.
• W3083095246 countsByYear W30830952462023 @default.
• W3083095246 crossrefType "journal-article" @default.
• W3083095246 hasAuthorship W3083095246A5004998372 @default.
• W3083095246 hasAuthorship W3083095246A5019686308 @default.
• W3083095246 hasAuthorship W3083095246A5039373148 @default.
• W3083095246 hasAuthorship W3083095246A5073101687 @default.
• W3083095246 hasConcept C126201875 @default.
• W3083095246 hasConcept C147789679 @default.
• W3083095246 hasConcept C160756335 @default.
• W3083095246 hasConcept C171250308 @default.
• W3083095246 hasConcept C17525397 @default.
• W3083095246 hasConcept C179104552 @default.
• W3083095246 hasConcept C185592680 @default.
• W3083095246 hasConcept C192562407 @default.
• W3083095246 hasConcept C21951064 @default.
• W3083095246 hasConcept C2777869211 @default.
• W3083095246 hasConcept C2779525745 @default.
• W3083095246 hasConcept C52859227 @default.
• W3083095246 hasConcept C552990157 @default.
• W3083095246 hasConcept C55493867 @default.
• W3083095246 hasConcept C55904794 @default.
• W3083095246 hasConceptScore W3083095246C126201875 @default.
• W3083095246 hasConceptScore W3083095246C147789679 @default.
• W3083095246 hasConceptScore W3083095246C160756335 @default.
• W3083095246 hasConceptScore W3083095246C171250308 @default.
• W3083095246 hasConceptScore W3083095246C17525397 @default.
• W3083095246 hasConceptScore W3083095246C179104552 @default.
• W3083095246 hasConceptScore W3083095246C185592680 @default.
• W3083095246 hasConceptScore W3083095246C192562407 @default.
• W3083095246 hasConceptScore W3083095246C21951064 @default.
• W3083095246 hasConceptScore W3083095246C2777869211 @default.
• W3083095246 hasConceptScore W3083095246C2779525745 @default.
• W3083095246 hasConceptScore W3083095246C52859227 @default.
• W3083095246 hasConceptScore W3083095246C552990157 @default.
• W3083095246 hasConceptScore W3083095246C55493867 @default.
• W3083095246 hasConceptScore W3083095246C55904794 @default.
• W3083095246 hasFunder F4320321001 @default.
• W3083095246 hasLocation W30830952461 @default.
• W3083095246 hasOpenAccess W3083095246 @default.
• W3083095246 hasPrimaryLocation W30830952461 @default.
• W3083095246 hasRelatedWork W1999194621 @default.
• W3083095246 hasRelatedWork W2018266715 @default.
• W3083095246 hasRelatedWork W2062013085 @default.
• W3083095246 hasRelatedWork W2092662973 @default.
• W3083095246 hasRelatedWork W2094108765 @default.
• W3083095246 hasRelatedWork W2175520887 @default.
• W3083095246 hasRelatedWork W2287638061 @default.
• W3083095246 hasRelatedWork W2375389133 @default.
• W3083095246 hasRelatedWork W2897008493 @default.

• next