Matches in SemOpenAlex for { <https://semopenalex.org/work/W3083432445> ?p ?o ?g. }
- W3083432445 abstract "Neuropsychological studies have revealed that patients with schizophrenia (SZ) have facial recognition difficulties and a reduced visual evoked N170 response to human faces. However, detailed neurophysiological evidence of this face processing deficit in SZ with a higher spatial resolution has yet to be acquired. In this study, we recorded visual evoked magnetoencephalography (MEG) and examined whether M170 (a magnetic counterpart of the N170) activity deficits are specific to faces in patients with chronic SZ.Participants were 26 patients with SZ and 26 healthy controls (HC). The M170 responses to faces and cars were recorded from whole-head MEG, and global field power over each temporal cortex was analyzed. The distributed M170 sources were also localized using a minimum-norm estimation (MNE) method. Correlational analyses between M170 responses and demographics/symptoms were performed.As expected, the M170 was significantly smaller in the SZ compared with the HC group in response to faces, but not to cars (faces: p = 0.01; cars: p = 0.55). The MNE analysis demonstrated that while the M170 was localized over the fusiform face area (FFA) in the HC group, visual-related brain regions other than the FFA were strongly activated in the SZ group in both stimulus conditions. The severity of negative symptoms was negatively correlated with M170 power (rho = -0.47, p = 0.01) in SZ. Within HC, there was a significant correlation between age and the M170 responses to faces averaged for both hemispheres (rho = 0.60, p = 0.001), while such a relationship was not observed in patients with SZ (rho = 0.09, p = 0.67).The present study showed specific reductions in the M170 response to human faces in patients with SZ. Our findings could suggest that SZ is characterized by face processing deficits that are associated with the severity of negative symptoms. Thus, we suggest that social cognition impairments in SZ might, at least in part, be caused by this functional face processing deficit." @default.
- W3083432445 created "2020-09-11" @default.
- W3083432445 creator A5002954377 @default.
- W3083432445 creator A5008063899 @default.
- W3083432445 creator A5030381424 @default.
- W3083432445 creator A5032026589 @default.
- W3083432445 creator A5033440579 @default.
- W3083432445 creator A5040835965 @default.
- W3083432445 creator A5045719470 @default.
- W3083432445 creator A5054421916 @default.
- W3083432445 creator A5066173446 @default.
- W3083432445 creator A5071786273 @default.
- W3083432445 creator A5075402019 @default.
- W3083432445 creator A5089383746 @default.
- W3083432445 date "2020-09-03" @default.
- W3083432445 modified "2023-09-25" @default.
- W3083432445 title "Neurophysiological Face Processing Deficits in Patients With Chronic Schizophrenia: An MEG Study" @default.
- W3083432445 cites W1848438530 @default.
- W3083432445 cites W1967583647 @default.
- W3083432445 cites W1973042443 @default.
- W3083432445 cites W1974713132 @default.
- W3083432445 cites W1977078963 @default.
- W3083432445 cites W1997950587 @default.
- W3083432445 cites W1998802214 @default.
- W3083432445 cites W2000454722 @default.
- W3083432445 cites W200959462 @default.
- W3083432445 cites W2013150886 @default.
- W3083432445 cites W2021864166 @default.
- W3083432445 cites W2022320465 @default.
- W3083432445 cites W2028828071 @default.
- W3083432445 cites W2053786275 @default.
- W3083432445 cites W2057165658 @default.
- W3083432445 cites W2066492582 @default.
- W3083432445 cites W2066877235 @default.
- W3083432445 cites W2067522567 @default.
- W3083432445 cites W2073744077 @default.
- W3083432445 cites W2078478412 @default.
- W3083432445 cites W2085369325 @default.
- W3083432445 cites W2096393622 @default.
- W3083432445 cites W2109970661 @default.
- W3083432445 cites W2112512931 @default.
- W3083432445 cites W2116490151 @default.
- W3083432445 cites W2121277032 @default.
- W3083432445 cites W2123432660 @default.
- W3083432445 cites W2134331559 @default.
- W3083432445 cites W2141796362 @default.
- W3083432445 cites W2147570002 @default.
- W3083432445 cites W2153985825 @default.
- W3083432445 cites W2155851653 @default.
- W3083432445 cites W2159760002 @default.
- W3083432445 cites W2579064236 @default.
- W3083432445 cites W2742602199 @default.
- W3083432445 cites W2801704870 @default.
- W3083432445 cites W2913588197 @default.
- W3083432445 cites W2914304155 @default.
- W3083432445 cites W2937804300 @default.
- W3083432445 cites W2939788595 @default.
- W3083432445 cites W2948079036 @default.
- W3083432445 cites W2970465400 @default.
- W3083432445 cites W2991549981 @default.
- W3083432445 cites W2998610849 @default.
- W3083432445 cites W3012601344 @default.
- W3083432445 cites W3033715094 @default.
- W3083432445 cites W3082212715 @default.
- W3083432445 cites W4230919856 @default.
- W3083432445 doi "https://doi.org/10.3389/fpsyt.2020.554844" @default.
- W3083432445 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7495506" @default.
- W3083432445 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33101080" @default.
- W3083432445 hasPublicationYear "2020" @default.
- W3083432445 type Work @default.
- W3083432445 sameAs 3083432445 @default.
- W3083432445 citedByCount "5" @default.
- W3083432445 countsByYear W30834324452021 @default.
- W3083432445 countsByYear W30834324452022 @default.
- W3083432445 countsByYear W30834324452023 @default.
- W3083432445 crossrefType "journal-article" @default.
- W3083432445 hasAuthorship W3083432445A5002954377 @default.
- W3083432445 hasAuthorship W3083432445A5008063899 @default.
- W3083432445 hasAuthorship W3083432445A5030381424 @default.
- W3083432445 hasAuthorship W3083432445A5032026589 @default.
- W3083432445 hasAuthorship W3083432445A5033440579 @default.
- W3083432445 hasAuthorship W3083432445A5040835965 @default.
- W3083432445 hasAuthorship W3083432445A5045719470 @default.
- W3083432445 hasAuthorship W3083432445A5054421916 @default.
- W3083432445 hasAuthorship W3083432445A5066173446 @default.
- W3083432445 hasAuthorship W3083432445A5071786273 @default.
- W3083432445 hasAuthorship W3083432445A5075402019 @default.
- W3083432445 hasAuthorship W3083432445A5089383746 @default.
- W3083432445 hasBestOaLocation W30834324451 @default.
- W3083432445 hasConcept C14216870 @default.
- W3083432445 hasConcept C152478114 @default.
- W3083432445 hasConcept C15744967 @default.
- W3083432445 hasConcept C169760540 @default.
- W3083432445 hasConcept C169900460 @default.
- W3083432445 hasConcept C180747234 @default.
- W3083432445 hasConcept C2779345533 @default.
- W3083432445 hasConcept C2779918689 @default.
- W3083432445 hasConcept C522805319 @default.
- W3083432445 hasConcept C548259974 @default.
- W3083432445 hasConcept C556910895 @default.