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• W3083555558 abstract "To evaluate the different definition of refractoriness in uveitis in the literature.We systematically searched the literature in order to identify definitions of refractory noninfectious uveitis in adult patients. A search strategy in the databases of MEDLINE and Scopus was used to find articles published between January 2005 and October 2018.Definitions of corticosteroids-refractoriness were related to two main concepts: persistence of inflammation despite the use of corticosteroid and recurrences above a dosage threshold. In terms of immunomodulatory therapy and biologic agents, we observed a great variety of definitions: persistence of inflammation, number of attacks, side effects or complications, symptoms, and best-corrected visual acuity.The results of this systematic review demonstrate the current lack of consensus on the definition for refractory uveitis, regardless of the treatment being used and revealed a new terminology based on a comprehensive and operational definition for each specific category of refractoriness." @default.
• W3083555558 created "2020-09-11" @default.
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• W3083555558 date "2020-09-04" @default.
• W3083555558 modified "2023-09-24" @default.
• W3083555558 title "Definition of Uveitis Refractory to Treatment: A Systematic Review in the Absence of a Consensus" @default.
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• W3083555558 doi "https://doi.org/10.1080/09273948.2020.1793369" @default.
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