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- W3083568356 abstract "Primary percutaneous coronary intervention (PCI) is the cornerstone of management for ST-elevation myocardial infarction (STEMI). However, large intracoronary thrombus burden complicates up to 70% of STEMI cases. Adjunct therapies described to address intracoronary thrombus include manual and mechanical thrombectomy, use of distal protection device and intracoronary anti-thrombotic therapies.This series demonstrates the use of intracoronary thrombolysis in the setting of large coronary thrombus, bifurcation lesions with vessel size mismatch, diffuse thrombosis without underlying plaque rupture, and improving coronary flow to allow vessel wiring and proceeding to definitive revascularization.Larger intracoronary thrombus burden correlates with greater infarct size, distal embolization, and the associated no-reflow phenomena, and propagates stent thrombosis, with subsequent increase in mortality and major adverse cardiac events. Intracoronary thrombolysis may provide useful adjunct therapy in highly selected STEMI cases to reduce intracoronary thrombus and facilitate revascularization." @default.
- W3083568356 created "2020-09-11" @default.
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- W3083568356 date "2020-09-04" @default.
- W3083568356 modified "2023-09-26" @default.
- W3083568356 title "The role of intracoronary thrombolysis in selected patients presenting with ST-elevation myocardial infarction: a case series" @default.
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- W3083568356 doi "https://doi.org/10.1093/ehjcr/ytaa227" @default.
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