Matches in SemOpenAlex for { <https://semopenalex.org/work/W3083733863> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W3083733863 endingPage "443" @default.
- W3083733863 startingPage "437" @default.
- W3083733863 abstract "OBJECTIVES To study the bone changes and curative effect of infliximab in patients with ankylosing spondylitis (AS). METHODS AS patients diagnosed and treated in Wuwei People's Hospital from January 2017 to March 2018 were collected as the study subjects of this study, and the patients were divided into INF group (n=40) and MTX group (n=40) according to the random number table. The expression levels of TNF-α and IL-33 before and after treatment were detected by enzyme-linked immunosorbent assay (ELISA), and bone changes before and after treatment were compared between the two groups. The ROC curves of TNF-α and IL-33 for efficacy prediction of AS were drawn and analyzed. RESULTS After treatment, the expression levels of serum TNF-α and IL-33 in patients in INF group were significantly lower than those in MTX group (P<0.001), and the improvement of bone erosion and tendon thickening in INF group was markedly higher than that in MTX group (P<0.001). The receiver operating characteristic (ROC) curve revealed that the area under the curve (AUC) of TNF-α for predicting efficacy was 0.939, and that of IL-33 was 0.853. CONCLUSIONS Infliximab can significantly improve the bone status and has a positive effect in patients with AS, and TNF-α and IL-33 are expected to be used as efficacy predictors of AS." @default.
- W3083733863 created "2020-09-11" @default.
- W3083733863 creator A5049745658 @default.
- W3083733863 creator A5054705652 @default.
- W3083733863 creator A5062871251 @default.
- W3083733863 creator A5065544354 @default.
- W3083733863 date "2020-09-01" @default.
- W3083733863 modified "2023-09-23" @default.
- W3083733863 title "Bone changes and curative effect of infliximab in patients with ankylosing spondylitis." @default.
- W3083733863 cites W1551830013 @default.
- W3083733863 cites W1966756689 @default.
- W3083733863 cites W1995963840 @default.
- W3083733863 cites W2016306307 @default.
- W3083733863 cites W2034148335 @default.
- W3083733863 cites W2052900499 @default.
- W3083733863 cites W2068354144 @default.
- W3083733863 cites W2110086427 @default.
- W3083733863 cites W2121605694 @default.
- W3083733863 cites W2131403115 @default.
- W3083733863 cites W2142657174 @default.
- W3083733863 cites W2151209074 @default.
- W3083733863 cites W2156878688 @default.
- W3083733863 cites W2166444828 @default.
- W3083733863 cites W2177824039 @default.
- W3083733863 cites W2360308304 @default.
- W3083733863 cites W2548028514 @default.
- W3083733863 cites W2578378488 @default.
- W3083733863 cites W2593871475 @default.
- W3083733863 cites W2943887251 @default.
- W3083733863 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7493436" @default.
- W3083733863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32877981" @default.
- W3083733863 hasPublicationYear "2020" @default.
- W3083733863 type Work @default.
- W3083733863 sameAs 3083733863 @default.
- W3083733863 citedByCount "1" @default.
- W3083733863 countsByYear W30837338632022 @default.
- W3083733863 crossrefType "journal-article" @default.
- W3083733863 hasAuthorship W3083733863A5049745658 @default.
- W3083733863 hasAuthorship W3083733863A5054705652 @default.
- W3083733863 hasAuthorship W3083733863A5062871251 @default.
- W3083733863 hasAuthorship W3083733863A5065544354 @default.
- W3083733863 hasConcept C126322002 @default.
- W3083733863 hasConcept C141071460 @default.
- W3083733863 hasConcept C17991360 @default.
- W3083733863 hasConcept C198451711 @default.
- W3083733863 hasConcept C2777138892 @default.
- W3083733863 hasConcept C2777402515 @default.
- W3083733863 hasConcept C58471807 @default.
- W3083733863 hasConcept C71924100 @default.
- W3083733863 hasConcept C76318530 @default.
- W3083733863 hasConcept C90924648 @default.
- W3083733863 hasConceptScore W3083733863C126322002 @default.
- W3083733863 hasConceptScore W3083733863C141071460 @default.
- W3083733863 hasConceptScore W3083733863C17991360 @default.
- W3083733863 hasConceptScore W3083733863C198451711 @default.
- W3083733863 hasConceptScore W3083733863C2777138892 @default.
- W3083733863 hasConceptScore W3083733863C2777402515 @default.
- W3083733863 hasConceptScore W3083733863C58471807 @default.
- W3083733863 hasConceptScore W3083733863C71924100 @default.
- W3083733863 hasConceptScore W3083733863C76318530 @default.
- W3083733863 hasConceptScore W3083733863C90924648 @default.
- W3083733863 hasIssue "3" @default.
- W3083733863 hasOpenAccess W3083733863 @default.
- W3083733863 hasRelatedWork W1974619242 @default.
- W3083733863 hasRelatedWork W1982058943 @default.
- W3083733863 hasRelatedWork W2055700074 @default.
- W3083733863 hasRelatedWork W2108077130 @default.
- W3083733863 hasRelatedWork W2256135848 @default.
- W3083733863 hasRelatedWork W2312502679 @default.
- W3083733863 hasRelatedWork W2323575466 @default.
- W3083733863 hasRelatedWork W2329195298 @default.
- W3083733863 hasRelatedWork W2335296398 @default.
- W3083733863 hasRelatedWork W2362590977 @default.
- W3083733863 hasRelatedWork W2373696506 @default.
- W3083733863 hasRelatedWork W2380822881 @default.
- W3083733863 hasRelatedWork W2387390423 @default.
- W3083733863 hasRelatedWork W2394743983 @default.
- W3083733863 hasRelatedWork W2557838400 @default.
- W3083733863 hasRelatedWork W2565039836 @default.
- W3083733863 hasRelatedWork W2605771783 @default.
- W3083733863 hasRelatedWork W2608748455 @default.
- W3083733863 hasRelatedWork W2900897885 @default.
- W3083733863 hasRelatedWork W3032162724 @default.
- W3083733863 hasVolume "20" @default.
- W3083733863 isParatext "false" @default.
- W3083733863 isRetracted "false" @default.
- W3083733863 magId "3083733863" @default.
- W3083733863 workType "article" @default.