Matches in SemOpenAlex for { <https://semopenalex.org/work/W3083770531> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3083770531 endingPage "S75" @default.
- W3083770531 startingPage "S71" @default.
- W3083770531 abstract "Objective This study aimed to describe the epidemiology of vertically transmitted sepsis (VS) and nosocomial sepsis (NOS) in very low birth weight (VLBW) neonates (birth weight ≤ 1,500 g) over the past 22 years in Spain. Study Design This is a retrospective analysis of prospectively collected VS and NOS in neonates from 1996 to 2018 in the 44 neonatal units integrated in the Spanish Neonatal Network Grupo Castrillo. Results A total of 2,676 episodes of VS were recorded in 2,196,129 live births (LBs; 1.2/1,000 LBs) over the study period (1996–2018). The incidence declined from 2.4 to 1 to 1.2/1,000 LBs (p < 0.0001). Of the 2,676 episodes, 95.7% were early onset (≤72 hours) and 4.3% cases late onset VS. Group B streptococcus (GBS) (33.1%) and E. coli (29.3%) were the most frequently isolated pathogen. The GBS incidence declined significantly from 1.25 to 0.21/1,000 LBs (p < 0.0001). E. coli incidence showed a significant increase trend in VLBW infants (p < 0.05). The global mortality per 1000 LBs decreased from 0.21 to 0.13/1,000. A total of 7,036 episodes of NOS involving 5,493 VLBW infants were registered over 20,935 neonatal admissions (NAs) in the study period (2006–2018). The incidence was 26.2 per 100 NAs. The median postnatal age at onset was 13 days (interquartile range [IQR]: 9–23 days). Around 80% of cases occurred in infants with a central line in place. Gram positive (GP) bacteria accounted for 66.2% with Staphylococcus epidermidis as the most frequently isolated pathogen, gram negative (GN) bacteria entailed 27.4%, and fungi 6.2%. Klebsiella sp. was the most common GN isolated and Candida albicans the most prevalent fungus. The overall mortality was 8.3%. Conclusion The causative pathogen of neonatal sepsis may change over time and between countries, therefore a national surveillance network based on a consensus definition could be essential to provide accurate information. Key Points" @default.
- W3083770531 created "2020-09-14" @default.
- W3083770531 creator A5020734146 @default.
- W3083770531 creator A5023591972 @default.
- W3083770531 creator A5025517368 @default.
- W3083770531 creator A5081015640 @default.
- W3083770531 date "2020-09-01" @default.
- W3083770531 modified "2023-09-26" @default.
- W3083770531 title "The Spanish National Network “Grupo Castrillo”: 22 Years of Nationwide Neonatal Infection Surveillance" @default.
- W3083770531 cites W1897158475 @default.
- W3083770531 cites W1966438479 @default.
- W3083770531 cites W1972040355 @default.
- W3083770531 cites W1996135473 @default.
- W3083770531 cites W2019019312 @default.
- W3083770531 cites W2047256761 @default.
- W3083770531 cites W2114685399 @default.
- W3083770531 cites W2136902196 @default.
- W3083770531 cites W2324411687 @default.
- W3083770531 cites W2324493551 @default.
- W3083770531 cites W2771759037 @default.
- W3083770531 cites W71980121 @default.
- W3083770531 doi "https://doi.org/10.1055/s-0040-1714256" @default.
- W3083770531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32898887" @default.
- W3083770531 hasPublicationYear "2020" @default.
- W3083770531 type Work @default.
- W3083770531 sameAs 3083770531 @default.
- W3083770531 citedByCount "6" @default.
- W3083770531 countsByYear W30837705312021 @default.
- W3083770531 countsByYear W30837705312022 @default.
- W3083770531 countsByYear W30837705312023 @default.
- W3083770531 crossrefType "journal-article" @default.
- W3083770531 hasAuthorship W3083770531A5020734146 @default.
- W3083770531 hasAuthorship W3083770531A5023591972 @default.
- W3083770531 hasAuthorship W3083770531A5025517368 @default.
- W3083770531 hasAuthorship W3083770531A5081015640 @default.
- W3083770531 hasConcept C107130276 @default.
- W3083770531 hasConcept C119060515 @default.
- W3083770531 hasConcept C120665830 @default.
- W3083770531 hasConcept C121332964 @default.
- W3083770531 hasConcept C126322002 @default.
- W3083770531 hasConcept C167135981 @default.
- W3083770531 hasConcept C187212893 @default.
- W3083770531 hasConcept C2775953899 @default.
- W3083770531 hasConcept C2778384902 @default.
- W3083770531 hasConcept C2779083892 @default.
- W3083770531 hasConcept C2779234561 @default.
- W3083770531 hasConcept C54355233 @default.
- W3083770531 hasConcept C61511704 @default.
- W3083770531 hasConcept C66322754 @default.
- W3083770531 hasConcept C71924100 @default.
- W3083770531 hasConcept C86803240 @default.
- W3083770531 hasConceptScore W3083770531C107130276 @default.
- W3083770531 hasConceptScore W3083770531C119060515 @default.
- W3083770531 hasConceptScore W3083770531C120665830 @default.
- W3083770531 hasConceptScore W3083770531C121332964 @default.
- W3083770531 hasConceptScore W3083770531C126322002 @default.
- W3083770531 hasConceptScore W3083770531C167135981 @default.
- W3083770531 hasConceptScore W3083770531C187212893 @default.
- W3083770531 hasConceptScore W3083770531C2775953899 @default.
- W3083770531 hasConceptScore W3083770531C2778384902 @default.
- W3083770531 hasConceptScore W3083770531C2779083892 @default.
- W3083770531 hasConceptScore W3083770531C2779234561 @default.
- W3083770531 hasConceptScore W3083770531C54355233 @default.
- W3083770531 hasConceptScore W3083770531C61511704 @default.
- W3083770531 hasConceptScore W3083770531C66322754 @default.
- W3083770531 hasConceptScore W3083770531C71924100 @default.
- W3083770531 hasConceptScore W3083770531C86803240 @default.
- W3083770531 hasIssue "S 02" @default.
- W3083770531 hasLocation W30837705311 @default.
- W3083770531 hasOpenAccess W3083770531 @default.
- W3083770531 hasPrimaryLocation W30837705311 @default.
- W3083770531 hasRelatedWork W13777102 @default.
- W3083770531 hasRelatedWork W1996336860 @default.
- W3083770531 hasRelatedWork W2033170135 @default.
- W3083770531 hasRelatedWork W2056522463 @default.
- W3083770531 hasRelatedWork W2330504211 @default.
- W3083770531 hasRelatedWork W2342798238 @default.
- W3083770531 hasRelatedWork W2608873815 @default.
- W3083770531 hasRelatedWork W2805963955 @default.
- W3083770531 hasRelatedWork W3099009888 @default.
- W3083770531 hasRelatedWork W3201719342 @default.
- W3083770531 hasVolume "37" @default.
- W3083770531 isParatext "false" @default.
- W3083770531 isRetracted "false" @default.
- W3083770531 magId "3083770531" @default.
- W3083770531 workType "article" @default.