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- W3083851647 endingPage "118377" @default.
- W3083851647 startingPage "118377" @default.
- W3083851647 abstract "The endothelium is the innermost vascular lining performing significant roles all over the human body while maintaining the blood pressure at physiological levels. Malfunction of endothelium is thus recognized as a biomarker linked with many vascular diseases including but not limited to atherosclerosis, hypertension and thrombosis. Alternatively, prevention of endothelial malfunctioning or regulating the functions of its associated physiological partners like endothelial nitric oxide synthase can prevent the associated vascular disorders which account for the highest death toll worldwide. While many anti-hypertensive drugs are available commercially, a comprehensive description of the key physiological roles of the endothelium and its regulation by endothelial nitric oxide synthase or vice versa is the need of the hour to understand its contribution in vascular homeostasis. This, in turn, will help in designing new therapeutics targeting endothelial nitric oxide synthase or its interacting partners present in the cellular pool. This review describes the central role of vascular endothelium in the regulation of endothelial nitric oxide synthase while outlining the emerging drug targets present in the vasculature with potential to treat vascular disorders including hypertension." @default.
- W3083851647 created "2020-09-14" @default.
- W3083851647 creator A5033785724 @default.
- W3083851647 creator A5047378398 @default.
- W3083851647 creator A5075373540 @default.
- W3083851647 date "2020-10-01" @default.
- W3083851647 modified "2023-10-18" @default.
- W3083851647 title "Functional implications of vascular endothelium in regulation of endothelial nitric oxide synthesis to control blood pressure and cardiac functions" @default.
- W3083851647 cites W1514239588 @default.
- W3083851647 cites W1553826095 @default.
- W3083851647 cites W1574772203 @default.
- W3083851647 cites W1578616085 @default.
- W3083851647 cites W1678800844 @default.
- W3083851647 cites W1937645347 @default.
- W3083851647 cites W1947196249 @default.
- W3083851647 cites W1964188498 @default.
- W3083851647 cites W1968326337 @default.
- W3083851647 cites W1968813770 @default.
- W3083851647 cites W1969703987 @default.
- W3083851647 cites W1969841262 @default.
- W3083851647 cites W1969898963 @default.
- W3083851647 cites W1970274019 @default.
- W3083851647 cites W1971126975 @default.
- W3083851647 cites W1971321175 @default.
- W3083851647 cites W1971686701 @default.
- W3083851647 cites W1972049213 @default.
- W3083851647 cites W1974081986 @default.
- W3083851647 cites W1974936925 @default.
- W3083851647 cites W1975628529 @default.
- W3083851647 cites W1975868044 @default.
- W3083851647 cites W1978245407 @default.
- W3083851647 cites W1978629923 @default.
- W3083851647 cites W1978891369 @default.
- W3083851647 cites W1980406827 @default.
- W3083851647 cites W1980684428 @default.
- W3083851647 cites W1981634237 @default.
- W3083851647 cites W1982471919 @default.
- W3083851647 cites W1985925852 @default.
- W3083851647 cites W1986437440 @default.
- W3083851647 cites W1990065551 @default.
- W3083851647 cites W1993522596 @default.
- W3083851647 cites W1993825065 @default.
- W3083851647 cites W1994768696 @default.
- W3083851647 cites W1995931698 @default.
- W3083851647 cites W1996502270 @default.
- W3083851647 cites W1996537616 @default.
- W3083851647 cites W1996940198 @default.
- W3083851647 cites W1997023449 @default.
- W3083851647 cites W2000075945 @default.
- W3083851647 cites W2002154995 @default.
- W3083851647 cites W2003075078 @default.
- W3083851647 cites W2003801493 @default.
- W3083851647 cites W2004175200 @default.
- W3083851647 cites W2004398529 @default.
- W3083851647 cites W2004804839 @default.
- W3083851647 cites W2007115760 @default.
- W3083851647 cites W2007223406 @default.
- W3083851647 cites W2011593158 @default.
- W3083851647 cites W2013475025 @default.
- W3083851647 cites W2015989606 @default.
- W3083851647 cites W2017683461 @default.
- W3083851647 cites W2017967250 @default.
- W3083851647 cites W2020702043 @default.
- W3083851647 cites W2020764743 @default.
- W3083851647 cites W2021994429 @default.
- W3083851647 cites W2022574364 @default.
- W3083851647 cites W2023204701 @default.
- W3083851647 cites W2023502006 @default.
- W3083851647 cites W2024185487 @default.
- W3083851647 cites W2024263079 @default.
- W3083851647 cites W2026138134 @default.
- W3083851647 cites W2026433673 @default.
- W3083851647 cites W2026483758 @default.
- W3083851647 cites W2026585864 @default.
- W3083851647 cites W2028671428 @default.
- W3083851647 cites W2028825823 @default.
- W3083851647 cites W2028880044 @default.
- W3083851647 cites W2029397220 @default.
- W3083851647 cites W2035433779 @default.
- W3083851647 cites W2035508242 @default.
- W3083851647 cites W2036336318 @default.
- W3083851647 cites W2036886710 @default.
- W3083851647 cites W2038250633 @default.
- W3083851647 cites W2038965219 @default.
- W3083851647 cites W2042631529 @default.
- W3083851647 cites W2044013576 @default.
- W3083851647 cites W2044451058 @default.
- W3083851647 cites W2045786338 @default.
- W3083851647 cites W2050548878 @default.
- W3083851647 cites W2055114314 @default.
- W3083851647 cites W2055824264 @default.
- W3083851647 cites W2057257230 @default.
- W3083851647 cites W2057366321 @default.
- W3083851647 cites W2057687781 @default.
- W3083851647 cites W2057919250 @default.
- W3083851647 cites W2059628610 @default.
- W3083851647 cites W2061409122 @default.
- W3083851647 cites W2061410859 @default.