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- W3083852020 abstract "The ongoing pandemic due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has so far infected about 2.42 × 107 (as at 27 August 2020) subjects with more than 820,000 deaths. It is the third zoonotic coronavirus-dependent outbreak in the last twenty years and represents a major infective threat for public health worldwide. A main aspect of the infection, in analogy to other viral infections, is the so-called “cytokine storm”, an inappropriate molecular response to virus spread which plays major roles in tissue and organ damage. Immunological therapies, including vaccines and humanized monoclonal antibodies, have been proposed as major strategies for prevention and treatment of the disease. Accordingly, a detailed mechanistic knowledge of the molecular events with which the virus infects cells and induces an immunological response appears necessary. In this review, we will report details of the initial process of SARS-CoV-2 cellular entry with major emphasis on the maturation of the spike protein. Then, a particular focus will be devoted to describe the possible mechanisms by which dendritic cells, a major cellular component of innate and adaptive immune responses, may play a role in the spread of the virus in the human body and in the clinical evolution of the disease." @default.
- W3083852020 created "2020-09-14" @default.
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- W3083852020 date "2020-09-08" @default.
- W3083852020 modified "2023-09-30" @default.
- W3083852020 title "Dendritic Cells and SARS-CoV-2 Infection: Still an Unclarified Connection" @default.
- W3083852020 cites W1859742880 @default.
- W3083852020 cites W1947409115 @default.
- W3083852020 cites W1966238900 @default.
- W3083852020 cites W1969248281 @default.
- W3083852020 cites W1972032770 @default.
- W3083852020 cites W1985970823 @default.
- W3083852020 cites W1990283625 @default.
- W3083852020 cites W2026178330 @default.
- W3083852020 cites W2028961398 @default.
- W3083852020 cites W2033330877 @default.
- W3083852020 cites W2033546768 @default.
- W3083852020 cites W2034273529 @default.
- W3083852020 cites W2035575900 @default.
- W3083852020 cites W2038918691 @default.
- W3083852020 cites W2052181661 @default.
- W3083852020 cites W2057513374 @default.
- W3083852020 cites W2058353078 @default.
- W3083852020 cites W2058780476 @default.
- W3083852020 cites W2067455871 @default.
- W3083852020 cites W2067560247 @default.
- W3083852020 cites W2067956701 @default.
- W3083852020 cites W2073197945 @default.
- W3083852020 cites W2092074976 @default.
- W3083852020 cites W2092162071 @default.
- W3083852020 cites W2098459942 @default.
- W3083852020 cites W2098576769 @default.
- W3083852020 cites W2113530888 @default.
- W3083852020 cites W2140267042 @default.
- W3083852020 cites W2143072084 @default.
- W3083852020 cites W2143640866 @default.
- W3083852020 cites W2152329221 @default.
- W3083852020 cites W2158922816 @default.
- W3083852020 cites W2163499692 @default.
- W3083852020 cites W2169109442 @default.
- W3083852020 cites W2286326426 @default.
- W3083852020 cites W2337855427 @default.
- W3083852020 cites W2410614396 @default.
- W3083852020 cites W2470646526 @default.
- W3083852020 cites W2555881147 @default.
- W3083852020 cites W2587763458 @default.
- W3083852020 cites W2596865928 @default.
- W3083852020 cites W2610420640 @default.
- W3083852020 cites W2781617771 @default.
- W3083852020 cites W2790537823 @default.
- W3083852020 cites W2801658748 @default.
- W3083852020 cites W2803031254 @default.
- W3083852020 cites W2945668436 @default.
- W3083852020 cites W2981138464 @default.
- W3083852020 cites W2990585428 @default.
- W3083852020 cites W3004197626 @default.
- W3083852020 cites W3004280078 @default.
- W3083852020 cites W3005409321 @default.
- W3083852020 cites W3005655936 @default.
- W3083852020 cites W3007268848 @default.
- W3083852020 cites W3007643904 @default.
- W3083852020 cites W3009912996 @default.
- W3083852020 cites W3010020071 @default.
- W3083852020 cites W3010848803 @default.
- W3083852020 cites W3011127849 @default.
- W3083852020 cites W3011201358 @default.
- W3083852020 cites W3011483298 @default.
- W3083852020 cites W3013036799 @default.
- W3083852020 cites W3013302817 @default.
- W3083852020 cites W3013730242 @default.
- W3083852020 cites W3013843138 @default.
- W3083852020 cites W3013855790 @default.
- W3083852020 cites W3014662258 @default.
- W3083852020 cites W3015134137 @default.
- W3083852020 cites W3015807479 @default.
- W3083852020 cites W3015981483 @default.
- W3083852020 cites W3016393661 @default.
- W3083852020 cites W3016473145 @default.
- W3083852020 cites W3016508437 @default.
- W3083852020 cites W3016572296 @default.
- W3083852020 cites W3016574998 @default.
- W3083852020 cites W3016591679 @default.
- W3083852020 cites W3016655948 @default.
- W3083852020 cites W3016858511 @default.
- W3083852020 cites W3017108368 @default.
- W3083852020 cites W3017125154 @default.
- W3083852020 cites W3017200596 @default.
- W3083852020 cites W3017287557 @default.
- W3083852020 cites W3018517500 @default.
- W3083852020 cites W3019906742 @default.
- W3083852020 cites W3020695284 @default.
- W3083852020 cites W3020710323 @default.
- W3083852020 cites W3021484935 @default.