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- W3083943178 abstract "Abstract In recent years, green synthesis of nanoparticles has been the cornerstone of development of nanotechnology and its applications, as it emphasizes on promoting environmental sustainability. The aim of the present study was to investigate the potential health benefits of the green-synthesized titanium nanoparticles (TiO 2 NPs). TiO 2 NPs were synthesized using titanium( iv ) isopropoxide and lupin bean extract. The synthesized particles were characterized to assess the average particle size by dynamic light scattering, and X-ray diffraction method was used to study the crystalline nature. The average particle size recorded was 9.227 nm with a polydispersity index (PDI) of 0.382. The morphology of the particles was assessed by scanning electron microscope and transmission electron microscopy which showed varied shapes of the nanoparticles, uniform spherical and crystallite rod shaped. Further, the cytotoxic efficacy of the nanoparticles was assessed against the breast cancer (MCF-7) cell line using 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromidefor (MTT) assay. The antibacterial activity of the nanoparticles was evaluated against clinical pathogens via the disc diffusion assay. The key findings showed that the TiO 2 NPs exhibited potent cytotoxicity against the MCF-7 cell line with an IC 50 of 41.1 µg. It also showed profound antibacterial activity. Thus, the synthesized nanoparticles could have potential biomedical applications owing to their therapeutic efficacy." @default.
- W3083943178 created "2020-09-14" @default.
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- W3083943178 date "2020-08-29" @default.
- W3083943178 modified "2023-10-16" @default.
- W3083943178 title "Eco-synthesis and characterization of titanium nanoparticles: Testing its cytotoxicity and antibacterial effects" @default.
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- W3083943178 doi "https://doi.org/10.1515/gps-2020-0045" @default.
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