Matches in SemOpenAlex for { <https://semopenalex.org/work/W3083996333> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3083996333 endingPage "87" @default.
- W3083996333 startingPage "79" @default.
- W3083996333 abstract "PURPOSE The aim of this study was to explore the value of adjuvant chemotherapy in patients with early-stage ER/PR-positive mucinous carcinoma. METHODS We identified early-stage ER/PR-positive mucinous carcinoma patients in the Surveillance, Epidemiology, and End Results (SEER) database. We used propensity-score matching (PSM) analysis to eliminate selection bias and differences in baseline characteristics. Univariate and multivariate analyses were performed to identify significant prognostic factors. The primary outcomes were overall survival (OS) and breast cancer-specific survival (BCSS), which were evaluated with the Kaplan-Meier method. RESULTS After propensity score matching, 805 pairs were selected. Patients with early-stage ER/PR-positive mucinous adenocarcinoma in the chemotherapy group had a better OS, but not BCSS, than those in the nonchemotherapy group after PSM (OS: p < 0.001; BCSS: p = 0.285). After stratifying by tumor size and lymph node status, adjuvant chemotherapy could significantly improve the OS of early-stage ER/PR-positive patients with tumors larger than 3 cm (p = 0.004) if they had negative lymph nodes (LNs). For patients positive LNs, the OS was significantly different between the chemotherapy group and the non-chemotherapy group when the tumors were larger than 1 cm (T = 1-2.9 cm, p = 0.006; T＞3 cm, p = 0.049, respectively). CONCLUSION Adjuvant chemotherapy maybe improves prognosis in patients with negative LNs and tumors larger than 3 cm, or patients with LNs metastasis and tumors larger than 1 cm. We suggest considering clinical characteristics meanwhile when deciding chemotherapy or not. Randomized controlled trials (RCT) are expected to confirm our results in the future." @default.
- W3083996333 created "2020-09-14" @default.
- W3083996333 creator A5020631350 @default.
- W3083996333 creator A5034733312 @default.
- W3083996333 creator A5039729883 @default.
- W3083996333 creator A5045873809 @default.
- W3083996333 creator A5052217154 @default.
- W3083996333 creator A5052594077 @default.
- W3083996333 creator A5060667885 @default.
- W3083996333 creator A5068190515 @default.
- W3083996333 creator A5084018016 @default.
- W3083996333 creator A5088880132 @default.
- W3083996333 date "2020-12-01" @default.
- W3083996333 modified "2023-10-12" @default.
- W3083996333 title "Adjuvant chemotherapy could benefit early-stage ER/PR positive mucinous breast cancer: A SEER-based analysis" @default.
- W3083996333 cites W1872153082 @default.
- W3083996333 cites W1972626053 @default.
- W3083996333 cites W1992316198 @default.
- W3083996333 cites W1993399840 @default.
- W3083996333 cites W2007550393 @default.
- W3083996333 cites W2028040032 @default.
- W3083996333 cites W2028236537 @default.
- W3083996333 cites W2053977751 @default.
- W3083996333 cites W2126049444 @default.
- W3083996333 cites W2160377567 @default.
- W3083996333 cites W2399881089 @default.
- W3083996333 cites W2509844702 @default.
- W3083996333 cites W2533610315 @default.
- W3083996333 cites W2773340921 @default.
- W3083996333 cites W2900898778 @default.
- W3083996333 cites W2906453797 @default.
- W3083996333 cites W2937965163 @default.
- W3083996333 cites W2976499962 @default.
- W3083996333 cites W2980167140 @default.
- W3083996333 doi "https://doi.org/10.1016/j.breast.2020.09.003" @default.
- W3083996333 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7502365" @default.
- W3083996333 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32947149" @default.
- W3083996333 hasPublicationYear "2020" @default.
- W3083996333 type Work @default.
- W3083996333 sameAs 3083996333 @default.
- W3083996333 citedByCount "3" @default.
- W3083996333 countsByYear W30839963332021 @default.
- W3083996333 countsByYear W30839963332022 @default.
- W3083996333 crossrefType "journal-article" @default.
- W3083996333 hasAuthorship W3083996333A5020631350 @default.
- W3083996333 hasAuthorship W3083996333A5034733312 @default.
- W3083996333 hasAuthorship W3083996333A5039729883 @default.
- W3083996333 hasAuthorship W3083996333A5045873809 @default.
- W3083996333 hasAuthorship W3083996333A5052217154 @default.
- W3083996333 hasAuthorship W3083996333A5052594077 @default.
- W3083996333 hasAuthorship W3083996333A5060667885 @default.
- W3083996333 hasAuthorship W3083996333A5068190515 @default.
- W3083996333 hasAuthorship W3083996333A5084018016 @default.
- W3083996333 hasAuthorship W3083996333A5088880132 @default.
- W3083996333 hasBestOaLocation W30839963331 @default.
- W3083996333 hasConcept C121608353 @default.
- W3083996333 hasConcept C126322002 @default.
- W3083996333 hasConcept C143998085 @default.
- W3083996333 hasConcept C146357865 @default.
- W3083996333 hasConcept C151730666 @default.
- W3083996333 hasConcept C2776694085 @default.
- W3083996333 hasConcept C2777863537 @default.
- W3083996333 hasConcept C29456083 @default.
- W3083996333 hasConcept C3018227240 @default.
- W3083996333 hasConcept C530470458 @default.
- W3083996333 hasConcept C71924100 @default.
- W3083996333 hasConcept C86803240 @default.
- W3083996333 hasConceptScore W3083996333C121608353 @default.
- W3083996333 hasConceptScore W3083996333C126322002 @default.
- W3083996333 hasConceptScore W3083996333C143998085 @default.
- W3083996333 hasConceptScore W3083996333C146357865 @default.
- W3083996333 hasConceptScore W3083996333C151730666 @default.
- W3083996333 hasConceptScore W3083996333C2776694085 @default.
- W3083996333 hasConceptScore W3083996333C2777863537 @default.
- W3083996333 hasConceptScore W3083996333C29456083 @default.
- W3083996333 hasConceptScore W3083996333C3018227240 @default.
- W3083996333 hasConceptScore W3083996333C530470458 @default.
- W3083996333 hasConceptScore W3083996333C71924100 @default.
- W3083996333 hasConceptScore W3083996333C86803240 @default.
- W3083996333 hasFunder F4320321001 @default.
- W3083996333 hasLocation W30839963331 @default.
- W3083996333 hasOpenAccess W3083996333 @default.
- W3083996333 hasPrimaryLocation W30839963331 @default.
- W3083996333 hasRelatedWork W167319750 @default.
- W3083996333 hasRelatedWork W2364515834 @default.
- W3083996333 hasRelatedWork W2369039771 @default.
- W3083996333 hasRelatedWork W2370076106 @default.
- W3083996333 hasRelatedWork W2386205804 @default.
- W3083996333 hasRelatedWork W2413232125 @default.
- W3083996333 hasRelatedWork W2588049562 @default.
- W3083996333 hasRelatedWork W3029632585 @default.
- W3083996333 hasRelatedWork W3162555034 @default.
- W3083996333 hasRelatedWork W4283517943 @default.
- W3083996333 hasVolume "54" @default.
- W3083996333 isParatext "false" @default.
- W3083996333 isRetracted "false" @default.
- W3083996333 magId "3083996333" @default.
- W3083996333 workType "article" @default.