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• W3084014794 abstract "Pegaharines A–G (1–6), six novel β-carboline alkaloids representing three types of skeleton, were isolated from the seeds of Peganum harmala. Compound 1 is a peculiar β-carboline alkaloid characterized by the unprecedented carbon skeleton of an azepine–indole system. Compounds 3–6 represent the first examples of heterodimers constructed from rare tetracyclic β-carboline and classic tricyclic β-carboline alkaloids. Compounds 1 and 2 were characterized by X-ray crystallography. Compound 4 exhibited strong antiviral activity against HSV-2, with an IC50 value of 2.12 ± 0.14 μM." @default.
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• W3084014794 date "2020-09-08" @default.
• W3084014794 modified "2023-10-16" @default.
• W3084014794 title "β-Carboline Alkaloids from the Seeds of <i>Peganum harmala</i> and Their Anti-HSV-2 Virus Activities" @default.
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• W3084014794 doi "https://doi.org/10.1021/acs.orglett.0c02650" @default.
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