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• W3084082007 abstract "To evaluate the serum levels of adiponectin and leptin and their relationship with nutritional variables during pregnancy in adolescents.This prospective cohort study evaluated eutrophic pregnant adolescents (body mass index [BMI], 18.5-24.9 kg/m2) during the 3 gestational trimesters (first, 10-14 weeks; second, 24-28 weeks; and third, 30-34 weeks). Serum adiponectin and leptin concentrations were measured using the enzyme-linked immunosorbent assay method. The relationship of these adipokines with the pre-gestational BMI, gestational weight gain, weight at the time of sample collection, and newborn weight were evaluated. Analysis of variance and the Kruskal-Wallis test were used for statistical analysis.The study group comprised 62 pregnant adolescents. The serum concentration of adiponectin showed a significant difference between the first and third trimesters (P=0.003), which decreased during pregnancy, but unrelated to nutritional variables. Serum leptin levels increased throughout the pregnancy (P<0.0001) and showed a positive correlation with pre-gestational BMI, total weight gain, pregnancy weight at the time of sample collection, and newborns' weight.Serum levels of adiponectin and leptin vary inversely throughout pregnancy. This pattern in adolescents is similar to that observed in adults. Moreover, leptin concentrations increased throughout pregnancy, and they were positively correlated with all variables evaluated." @default.
• W3084082007 created "2020-09-14" @default.
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• W3084082007 date "2020-11-15" @default.
• W3084082007 modified "2023-10-09" @default.
• W3084082007 title "Blood level of adipokines and nutritional status variables in adolescent pregnancy" @default.
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• W3084082007 doi "https://doi.org/10.5468/ogs.20102" @default.
• W3084082007 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7677068" @default.
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