FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3084091731> ?p ?o ?g. }

• W3084091731 endingPage "9013" @default.
• W3084091731 startingPage "9005" @default.
• W3084091731 abstract "Caspase recruitment domain-containing protein 9 (CARD9) is expressed at high levels in bone marrow cells and has a crucial role in innate immunity. Current studies indicate that CARD9 also plays a key role in tumor progression, but there are few reports on the role of CARD9 in lung cancer. The aim of this study was to clarify the role of CARD9 in lung adenocarcinoma.Lung adenocarcinoma tumor samples from 74 patients who underwent complete resection at Kobe University Hospital from January 2014 to December 2014 were analyzed by immunohistochemistry. The role of CARD9 in cancer cells was analyzed using lung cancer cell lines treated with CARD9 siRNA.High expression of CARD9 was observed in 32.4% of tumors, and compared to low expression of CARD9, high expression was associated with poorer overall survival (P = 0.0365). Univariate and multivariate analyses showed that high expression of CARD9 was an independent prognostic factor. Knockdown of CARD9 in lung adenocarcinoma cells inhibited proliferation but did not increase apoptosis. In addition, CARD9 activated the NF-κB pathway in a lung adenocarcinoma cell line.CARD9 was shown to be an independent prognostic factor of poor outcome for lung cancer and may represent a molecular target for treatment." @default.
• W3084091731 created "2020-09-14" @default.
• W3084091731 creator A5000662769 @default.
• W3084091731 creator A5008560120 @default.
• W3084091731 creator A5009114502 @default.
• W3084091731 creator A5010566372 @default.
• W3084091731 creator A5022261966 @default.
• W3084091731 creator A5025499235 @default.
• W3084091731 creator A5031991190 @default.
• W3084091731 creator A5033360643 @default.
• W3084091731 creator A5041182728 @default.
• W3084091731 creator A5051847895 @default.
• W3084091731 creator A5062267947 @default.
• W3084091731 creator A5080924704 @default.
• W3084091731 creator A5082268022 @default.
• W3084091731 creator A5087151333 @default.
• W3084091731 creator A5088416811 @default.
• W3084091731 date "2020-09-01" @default.
• W3084091731 modified "2023-10-04" @default.
• W3084091731 title "<p>Caspase Recruitment Domain-Containing Protein 9 Expression is a Novel Prognostic Factor for Lung Adenocarcinoma</p>" @default.
• W3084091731 cites W1740332796 @default.
• W3084091731 cites W1881072801 @default.
• W3084091731 cites W1971240021 @default.
• W3084091731 cites W1973037661 @default.
• W3084091731 cites W1974366841 @default.
• W3084091731 cites W1990530060 @default.
• W3084091731 cites W2027342983 @default.
• W3084091731 cites W2031495220 @default.
• W3084091731 cites W2054951030 @default.
• W3084091731 cites W2062434563 @default.
• W3084091731 cites W2096560299 @default.
• W3084091731 cites W2121960517 @default.
• W3084091731 cites W2129242841 @default.
• W3084091731 cites W2129825481 @default.
• W3084091731 cites W2137652355 @default.
• W3084091731 cites W2138934663 @default.
• W3084091731 cites W2182482244 @default.
• W3084091731 cites W2591717879 @default.
• W3084091731 cites W2766149732 @default.
• W3084091731 cites W2790060323 @default.
• W3084091731 cites W2792227699 @default.
• W3084091731 cites W2921241315 @default.
• W3084091731 cites W2921309119 @default.
• W3084091731 cites W2960096397 @default.
• W3084091731 cites W2970396105 @default.
• W3084091731 cites W2987464445 @default.
• W3084091731 cites W2991233740 @default.
• W3084091731 cites W2993505735 @default.
• W3084091731 doi "https://doi.org/10.2147/ott.s265539" @default.
• W3084091731 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7498929" @default.
• W3084091731 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32982291" @default.
• W3084091731 hasPublicationYear "2020" @default.
• W3084091731 type Work @default.
• W3084091731 sameAs 3084091731 @default.
• W3084091731 citedByCount "2" @default.
• W3084091731 countsByYear W30840917312022 @default.
• W3084091731 countsByYear W30840917312023 @default.
• W3084091731 crossrefType "journal-article" @default.
• W3084091731 hasAuthorship W3084091731A5000662769 @default.
• W3084091731 hasAuthorship W3084091731A5008560120 @default.
• W3084091731 hasAuthorship W3084091731A5009114502 @default.
• W3084091731 hasAuthorship W3084091731A5010566372 @default.
• W3084091731 hasAuthorship W3084091731A5022261966 @default.
• W3084091731 hasAuthorship W3084091731A5025499235 @default.
• W3084091731 hasAuthorship W3084091731A5031991190 @default.
• W3084091731 hasAuthorship W3084091731A5033360643 @default.
• W3084091731 hasAuthorship W3084091731A5041182728 @default.
• W3084091731 hasAuthorship W3084091731A5051847895 @default.
• W3084091731 hasAuthorship W3084091731A5062267947 @default.
• W3084091731 hasAuthorship W3084091731A5080924704 @default.
• W3084091731 hasAuthorship W3084091731A5082268022 @default.
• W3084091731 hasAuthorship W3084091731A5087151333 @default.
• W3084091731 hasAuthorship W3084091731A5088416811 @default.
• W3084091731 hasBestOaLocation W30840917311 @default.
• W3084091731 hasConcept C121608353 @default.
• W3084091731 hasConcept C126322002 @default.
• W3084091731 hasConcept C142724271 @default.
• W3084091731 hasConcept C143998085 @default.
• W3084091731 hasConcept C173396325 @default.
• W3084091731 hasConcept C190283241 @default.
• W3084091731 hasConcept C204232928 @default.
• W3084091731 hasConcept C2776256026 @default.
• W3084091731 hasConcept C2777714996 @default.
• W3084091731 hasConcept C2781182431 @default.
• W3084091731 hasConcept C502942594 @default.
• W3084091731 hasConcept C55493867 @default.
• W3084091731 hasConcept C71924100 @default.
• W3084091731 hasConcept C86803240 @default.
• W3084091731 hasConceptScore W3084091731C121608353 @default.
• W3084091731 hasConceptScore W3084091731C126322002 @default.
• W3084091731 hasConceptScore W3084091731C142724271 @default.
• W3084091731 hasConceptScore W3084091731C143998085 @default.
• W3084091731 hasConceptScore W3084091731C173396325 @default.
• W3084091731 hasConceptScore W3084091731C190283241 @default.
• W3084091731 hasConceptScore W3084091731C204232928 @default.
• W3084091731 hasConceptScore W3084091731C2776256026 @default.
• W3084091731 hasConceptScore W3084091731C2777714996 @default.
• W3084091731 hasConceptScore W3084091731C2781182431 @default.

• next