Matches in SemOpenAlex for { <https://semopenalex.org/work/W3084260219> ?p ?o ?g. }
- W3084260219 endingPage "1008" @default.
- W3084260219 startingPage "1008" @default.
- W3084260219 abstract "Recent reports have pointed to the link between persistent inflammation, oxidative stress, and carcinogenesis; however most of the studies concerning the role of viruses in head and neck cancer (HNC) are focused mainly on one type of virus. Our present study aimed to study the relationship between Epstein–Barr virus/human papilloma virus (EBV/HPV) coinfection and glutathione peroxidase (GPx) and superoxide dismutase (SOD) level in oropharyngeal cancer. Fresh-frozen tumor tissue samples were collected from 128 patients with oropharyngeal cancer infected with EBV or HPV or with EBV/HPV coinfection. After DNA extraction, EBV and HPV DNA was detected using a polymerase chain reaction (PCR) assay. GPx and SOD activity was determined in homogenates of cancer tissue using diagnostic kits produced by Randox Laboratories. Both GPx and SOD activity was statistically lower in patients with EBV/HPV coinfection than in a single EBV or HPV infection. Analysis of GPx and SOD activity in relation to histological grading and tumor, node (TN) classification revealed that in poorly-differentiated tumors, the level of antioxidant enzymes was lower compared with well-differentiated lesions and in cases with greater tumor dimensions and lymph-node involvement, both GPx and SOD activity was decreased. Further studies are necessary to clarify the influence of interplay between EBV, HPV, and oxidative stress on malignant transformation of upper aerodigestive tract epithelial cells." @default.
- W3084260219 created "2020-09-14" @default.
- W3084260219 creator A5002357946 @default.
- W3084260219 creator A5004704339 @default.
- W3084260219 creator A5009623271 @default.
- W3084260219 creator A5078321123 @default.
- W3084260219 creator A5078479913 @default.
- W3084260219 creator A5081158348 @default.
- W3084260219 creator A5090277813 @default.
- W3084260219 date "2020-09-09" @default.
- W3084260219 modified "2023-10-06" @default.
- W3084260219 title "Glutathione Peroxidase (GPx) and Superoxide Dismutase (SOD) in Oropharyngeal Cancer Associated with EBV and HPV Coinfection" @default.
- W3084260219 cites W1581034919 @default.
- W3084260219 cites W1964760403 @default.
- W3084260219 cites W1965117407 @default.
- W3084260219 cites W1965947832 @default.
- W3084260219 cites W1969775662 @default.
- W3084260219 cites W1974438897 @default.
- W3084260219 cites W2017517248 @default.
- W3084260219 cites W2019514548 @default.
- W3084260219 cites W2023862933 @default.
- W3084260219 cites W2024087409 @default.
- W3084260219 cites W2025749731 @default.
- W3084260219 cites W2027527568 @default.
- W3084260219 cites W2029120392 @default.
- W3084260219 cites W2036199480 @default.
- W3084260219 cites W2046706645 @default.
- W3084260219 cites W2053857865 @default.
- W3084260219 cites W2076112714 @default.
- W3084260219 cites W2091328644 @default.
- W3084260219 cites W2103271921 @default.
- W3084260219 cites W2133042655 @default.
- W3084260219 cites W2151198049 @default.
- W3084260219 cites W2152350089 @default.
- W3084260219 cites W2171663071 @default.
- W3084260219 cites W2277129408 @default.
- W3084260219 cites W2282180989 @default.
- W3084260219 cites W2340212620 @default.
- W3084260219 cites W2382210120 @default.
- W3084260219 cites W2480418585 @default.
- W3084260219 cites W2547833277 @default.
- W3084260219 cites W2587457530 @default.
- W3084260219 cites W2621242384 @default.
- W3084260219 cites W2734268266 @default.
- W3084260219 cites W2750333573 @default.
- W3084260219 cites W2777632961 @default.
- W3084260219 cites W2889391353 @default.
- W3084260219 cites W2889482450 @default.
- W3084260219 cites W2956522195 @default.
- W3084260219 cites W2995167300 @default.
- W3084260219 cites W3015302445 @default.
- W3084260219 cites W4293247451 @default.
- W3084260219 doi "https://doi.org/10.3390/v12091008" @default.
- W3084260219 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7551554" @default.
- W3084260219 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32917014" @default.
- W3084260219 hasPublicationYear "2020" @default.
- W3084260219 type Work @default.
- W3084260219 sameAs 3084260219 @default.
- W3084260219 citedByCount "19" @default.
- W3084260219 countsByYear W30842602192021 @default.
- W3084260219 countsByYear W30842602192022 @default.
- W3084260219 countsByYear W30842602192023 @default.
- W3084260219 crossrefType "journal-article" @default.
- W3084260219 hasAuthorship W3084260219A5002357946 @default.
- W3084260219 hasAuthorship W3084260219A5004704339 @default.
- W3084260219 hasAuthorship W3084260219A5009623271 @default.
- W3084260219 hasAuthorship W3084260219A5078321123 @default.
- W3084260219 hasAuthorship W3084260219A5078479913 @default.
- W3084260219 hasAuthorship W3084260219A5081158348 @default.
- W3084260219 hasAuthorship W3084260219A5090277813 @default.
- W3084260219 hasBestOaLocation W30842602191 @default.
- W3084260219 hasConcept C121608353 @default.
- W3084260219 hasConcept C126322002 @default.
- W3084260219 hasConcept C142724271 @default.
- W3084260219 hasConcept C203014093 @default.
- W3084260219 hasConcept C203663253 @default.
- W3084260219 hasConcept C2522874641 @default.
- W3084260219 hasConcept C2775838275 @default.
- W3084260219 hasConcept C2776151105 @default.
- W3084260219 hasConcept C2777813720 @default.
- W3084260219 hasConcept C2778760513 @default.
- W3084260219 hasConcept C555283112 @default.
- W3084260219 hasConcept C71924100 @default.
- W3084260219 hasConcept C86803240 @default.
- W3084260219 hasConceptScore W3084260219C121608353 @default.
- W3084260219 hasConceptScore W3084260219C126322002 @default.
- W3084260219 hasConceptScore W3084260219C142724271 @default.
- W3084260219 hasConceptScore W3084260219C203014093 @default.
- W3084260219 hasConceptScore W3084260219C203663253 @default.
- W3084260219 hasConceptScore W3084260219C2522874641 @default.
- W3084260219 hasConceptScore W3084260219C2775838275 @default.
- W3084260219 hasConceptScore W3084260219C2776151105 @default.
- W3084260219 hasConceptScore W3084260219C2777813720 @default.
- W3084260219 hasConceptScore W3084260219C2778760513 @default.
- W3084260219 hasConceptScore W3084260219C555283112 @default.
- W3084260219 hasConceptScore W3084260219C71924100 @default.
- W3084260219 hasConceptScore W3084260219C86803240 @default.
- W3084260219 hasIssue "9" @default.