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- W3084283234 abstract "Background: Convulsive status epilepticus (CSE) is a medical emergency that is commonly encountered in the prehospital setting. In almost all prehospital settings, treatment is limited to benzodiazepines even though the standard of care in emergency departments includes second-line agents such as phenytoin. Methods: A literature search was conducted using PubMed and Google Scholar using the search terms ‘phenytoin’, ‘seizure’ or ‘convulsive’ and ‘prehospital’, ‘EMS’ or ‘ambulance’ or ‘emergency department’. Five articles were analysed and a narrative review formed. Results: Phenytoin is an effective and commonly used second-line anti-epileptic agent but there is a distinct lack of evidence on prehospital phenytoin. Phasing the introduction of phenytoin into practice while simultaneously running a well-designed research trial could provide data for prehospital providers and the wider health community. Conclusion: Management of CSE will continue to present challenges to prehospital providers. Promoting the introduction of phenytoin to select patients, administered by advanced clinicians, could be an excellent opportunity to generate much-needed clinical data and potentially reduce morbidity and mortality in CSE." @default.
- W3084283234 created "2020-09-14" @default.
- W3084283234 creator A5082919650 @default.
- W3084283234 date "2020-09-02" @default.
- W3084283234 modified "2023-09-25" @default.
- W3084283234 title "Feasibility of phenytoin as a paramedic-led second-line anti-epileptic drug" @default.
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- W3084283234 doi "https://doi.org/10.12968/jpar.2020.12.9.349" @default.
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