Matches in SemOpenAlex for { <https://semopenalex.org/work/W3084301618> ?p ?o ?g. }
- W3084301618 endingPage "605" @default.
- W3084301618 startingPage "564" @default.
- W3084301618 abstract "Per- and poly-fluoroalkyl substances (PFAS) encompass a large, heterogenous group of chemicals of potential concern to human health and the environment. Based on information for a few relatively well-understood PFAS such as perfluorooctane sulfonate and perfluorooctanoate, there is ample basis to suspect that at least a subset can be considered persistent, bioaccumulative, and/or toxic. However, data suitable for determining risks in either prospective or retrospective assessments are lacking for the majority of PFAS. In August 2019, the Society of Environmental Toxicology and Chemistry sponsored a workshop that focused on the state-of-the-science supporting risk assessment of PFAS. The present review summarizes discussions concerning the ecotoxicology and ecological risks of PFAS. First, we summarize currently available information relevant to problem formulation/prioritization, exposure, and hazard/effects of PFAS in the context of regulatory and ecological risk assessment activities from around the world. We then describe critical gaps and uncertainties relative to ecological risk assessments for PFAS and propose approaches to address these needs. Recommendations include the development of more comprehensive monitoring programs to support exposure assessment, an emphasis on research to support the formulation of predictive models for bioaccumulation, and the development of in silico, in vitro, and in vivo methods to efficiently assess biological effects for potentially sensitive species/endpoints. Addressing needs associated with assessing the ecological risk of PFAS will require cross-disciplinary approaches that employ both conventional and new methods in an integrated, resource-effective manner. Environ Toxicol Chem 2021;40:564-605. © 2020 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC. This article has been contributed to by US Government employees and their work is in the public domain in the USA." @default.
- W3084301618 created "2020-09-14" @default.
- W3084301618 creator A5013651599 @default.
- W3084301618 creator A5025057346 @default.
- W3084301618 creator A5038610645 @default.
- W3084301618 creator A5040025951 @default.
- W3084301618 creator A5041700802 @default.
- W3084301618 creator A5041739507 @default.
- W3084301618 creator A5056944733 @default.
- W3084301618 creator A5060344791 @default.
- W3084301618 creator A5064749712 @default.
- W3084301618 creator A5065662870 @default.
- W3084301618 creator A5066124490 @default.
- W3084301618 creator A5066656766 @default.
- W3084301618 creator A5074190500 @default.
- W3084301618 creator A5088913568 @default.
- W3084301618 date "2020-11-06" @default.
- W3084301618 modified "2023-10-15" @default.
- W3084301618 title "Assessing the Ecological Risks of Per‐ and Polyfluoroalkyl Substances: Current State‐of‐the Science and a Proposed Path Forward" @default.
- W3084301618 cites W113101877 @default.
- W3084301618 cites W1157411613 @default.
- W3084301618 cites W1422819559 @default.
- W3084301618 cites W1523050720 @default.
- W3084301618 cites W1593508271 @default.
- W3084301618 cites W1965345679 @default.
- W3084301618 cites W1971651829 @default.
- W3084301618 cites W1973073526 @default.
- W3084301618 cites W1973828273 @default.
- W3084301618 cites W1974264164 @default.
- W3084301618 cites W1974916973 @default.
- W3084301618 cites W1975700888 @default.
- W3084301618 cites W1976995085 @default.
- W3084301618 cites W1978586992 @default.
- W3084301618 cites W1980141451 @default.
- W3084301618 cites W1980343515 @default.
- W3084301618 cites W1981284081 @default.
- W3084301618 cites W1989021573 @default.
- W3084301618 cites W1990512060 @default.
- W3084301618 cites W1990618515 @default.
- W3084301618 cites W1990814794 @default.
- W3084301618 cites W1992591524 @default.
- W3084301618 cites W1994837801 @default.
- W3084301618 cites W1995448239 @default.
- W3084301618 cites W1995919892 @default.
- W3084301618 cites W1998148180 @default.
- W3084301618 cites W1999721282 @default.
- W3084301618 cites W2000089305 @default.
- W3084301618 cites W2001532754 @default.
- W3084301618 cites W2001911039 @default.
- W3084301618 cites W2002071646 @default.
- W3084301618 cites W2002378618 @default.
- W3084301618 cites W2004809711 @default.
- W3084301618 cites W2007370532 @default.
- W3084301618 cites W2008629909 @default.
- W3084301618 cites W2011582760 @default.
- W3084301618 cites W2014482541 @default.
- W3084301618 cites W2016300349 @default.
- W3084301618 cites W2016627968 @default.
- W3084301618 cites W2017300013 @default.
- W3084301618 cites W2018072518 @default.
- W3084301618 cites W2018431021 @default.
- W3084301618 cites W2018695982 @default.
- W3084301618 cites W2020361251 @default.
- W3084301618 cites W2020882905 @default.
- W3084301618 cites W2021338771 @default.
- W3084301618 cites W2025200531 @default.
- W3084301618 cites W2028866645 @default.
- W3084301618 cites W2029916104 @default.
- W3084301618 cites W2030637419 @default.
- W3084301618 cites W2033274619 @default.
- W3084301618 cites W2034132533 @default.
- W3084301618 cites W2036367214 @default.
- W3084301618 cites W2037945391 @default.
- W3084301618 cites W2039023381 @default.
- W3084301618 cites W2042700359 @default.
- W3084301618 cites W2042721894 @default.
- W3084301618 cites W2044155967 @default.
- W3084301618 cites W2049548465 @default.
- W3084301618 cites W2050292834 @default.
- W3084301618 cites W2050489977 @default.
- W3084301618 cites W2050700610 @default.
- W3084301618 cites W2054929131 @default.
- W3084301618 cites W2056843801 @default.
- W3084301618 cites W2057728053 @default.
- W3084301618 cites W2062019736 @default.
- W3084301618 cites W2062262087 @default.
- W3084301618 cites W2063255429 @default.
- W3084301618 cites W2063880712 @default.
- W3084301618 cites W2064507515 @default.
- W3084301618 cites W2067813964 @default.
- W3084301618 cites W2067834800 @default.
- W3084301618 cites W2068851177 @default.
- W3084301618 cites W2068975797 @default.
- W3084301618 cites W2069220274 @default.
- W3084301618 cites W2070300719 @default.
- W3084301618 cites W2072092931 @default.
- W3084301618 cites W2073160738 @default.
- W3084301618 cites W2073307277 @default.