Matches in SemOpenAlex for { <https://semopenalex.org/work/W3084889460> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W3084889460 abstract "Objectives: To revisit the trend of survival of systemic lupus erythematosus in a cohort of Chinese patients over 25 years Methods: Patients who fulfilled the 1997 ACR criteria for SLE and were followed in our hospital since 1995 were included. Patients were stratified into 2 groups according to the year of diagnosis: (1) 1995-2004; and (2) 2005-2018. Survival of patients was studied by Kaplan Meier’s analysis. Organ damage as assessed by the Systemic Lupus International Collaborating Clinics (SLICC) damage index (SDI) and causes of death in the first 10 years of SLE onset was compared between the two groups. Cox regression was used to study factors associated with survival. Results: A total of 1098 SLE patients were registered in our database. After excluding 157 patients diagnosed outside the time period of 1995-2018, 941 patients were studied (92% women). All were ethnic Chinese. The mean age of SLE onset was 35.1±14.4 years and the mean duration of observation was 13.1±6.6 years. Seventy-seven (8.2%) patients were lost to follow up. Groups 1 and 2 consisted of 364 and 577 patients, respectively. The mean SDI score at 10 years of disease onset was significantly higher in group 1 than group 2 patients (1.01±1.43 versus 0.57±0.94; p<0.01), particularly in the neuropsychiatric, musculoskeletal and gonadal domains. Within 10 years of SLE onset, 32 (8.8%) patients in group 1 and 25 (4.3%) patients in group 2 died (p=0.005). The 5- and 10-year cumulative survival rates were 93.6% and 91.0% in group 1; and 96.5% and 94.2% in group 2 patients, respectively (log rank test p=0.048). Infection accounted for more than half of the deaths in both groups. More group 1 than group 2 patients died of vascular events but the difference was not statistically significant. Cox regression showed that the age of SLE onset and damage score accrued at 10 years, but not the time period in which SLE was diagnosed, were significantly associated with mortality. Conclusions: The improvement in survival of our SLE patients is probably related to the accrual of less organ damage in the past 15 years." @default.
- W3084889460 created "2020-09-21" @default.
- W3084889460 creator A5006185236 @default.
- W3084889460 creator A5029220394 @default.
- W3084889460 creator A5033947419 @default.
- W3084889460 creator A5057647252 @default.
- W3084889460 creator A5089088625 @default.
- W3084889460 date "2020-09-11" @default.
- W3084889460 modified "2023-10-16" @default.
- W3084889460 title "Trend of Survival of a Cohort of Chinese Patients With Systemic Lupus Erythematosus Over 25 Years" @default.
- W3084889460 cites W1975599820 @default.
- W3084889460 cites W1995305096 @default.
- W3084889460 cites W1995365224 @default.
- W3084889460 cites W1995696260 @default.
- W3084889460 cites W2053367430 @default.
- W3084889460 cites W2061920256 @default.
- W3084889460 cites W2070527591 @default.
- W3084889460 cites W2073513756 @default.
- W3084889460 cites W2098311476 @default.
- W3084889460 cites W2108905161 @default.
- W3084889460 cites W2139198208 @default.
- W3084889460 cites W2151779481 @default.
- W3084889460 cites W2159012891 @default.
- W3084889460 cites W2162768263 @default.
- W3084889460 cites W2414937980 @default.
- W3084889460 cites W2744889237 @default.
- W3084889460 cites W2751907835 @default.
- W3084889460 cites W2766897198 @default.
- W3084889460 cites W2783280261 @default.
- W3084889460 cites W2800797568 @default.
- W3084889460 cites W2885203084 @default.
- W3084889460 cites W2885709189 @default.
- W3084889460 cites W2893981798 @default.
- W3084889460 cites W2909006646 @default.
- W3084889460 cites W2912591526 @default.
- W3084889460 cites W2915658509 @default.
- W3084889460 cites W2965730548 @default.
- W3084889460 cites W2979250283 @default.
- W3084889460 cites W2989675187 @default.
- W3084889460 cites W2993856287 @default.
- W3084889460 cites W3006146580 @default.
- W3084889460 doi "https://doi.org/10.3389/fmed.2020.00552" @default.
- W3084889460 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7516076" @default.
- W3084889460 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33015102" @default.
- W3084889460 hasPublicationYear "2020" @default.
- W3084889460 type Work @default.
- W3084889460 sameAs 3084889460 @default.
- W3084889460 citedByCount "12" @default.
- W3084889460 countsByYear W30848894602021 @default.
- W3084889460 countsByYear W30848894602022 @default.
- W3084889460 countsByYear W30848894602023 @default.
- W3084889460 crossrefType "journal-article" @default.
- W3084889460 hasAuthorship W3084889460A5006185236 @default.
- W3084889460 hasAuthorship W3084889460A5029220394 @default.
- W3084889460 hasAuthorship W3084889460A5033947419 @default.
- W3084889460 hasAuthorship W3084889460A5057647252 @default.
- W3084889460 hasAuthorship W3084889460A5089088625 @default.
- W3084889460 hasBestOaLocation W30848894601 @default.
- W3084889460 hasConcept C10515644 @default.
- W3084889460 hasConcept C126322002 @default.
- W3084889460 hasConcept C2776912625 @default.
- W3084889460 hasConcept C2779134260 @default.
- W3084889460 hasConcept C50382708 @default.
- W3084889460 hasConcept C71924100 @default.
- W3084889460 hasConcept C72563966 @default.
- W3084889460 hasConceptScore W3084889460C10515644 @default.
- W3084889460 hasConceptScore W3084889460C126322002 @default.
- W3084889460 hasConceptScore W3084889460C2776912625 @default.
- W3084889460 hasConceptScore W3084889460C2779134260 @default.
- W3084889460 hasConceptScore W3084889460C50382708 @default.
- W3084889460 hasConceptScore W3084889460C71924100 @default.
- W3084889460 hasConceptScore W3084889460C72563966 @default.
- W3084889460 hasLocation W30848894601 @default.
- W3084889460 hasLocation W30848894602 @default.
- W3084889460 hasLocation W30848894603 @default.
- W3084889460 hasOpenAccess W3084889460 @default.
- W3084889460 hasPrimaryLocation W30848894601 @default.
- W3084889460 hasRelatedWork W2270600280 @default.
- W3084889460 hasRelatedWork W2315085516 @default.
- W3084889460 hasRelatedWork W2316407790 @default.
- W3084889460 hasRelatedWork W2603773853 @default.
- W3084889460 hasRelatedWork W4200329600 @default.
- W3084889460 hasRelatedWork W4200489086 @default.
- W3084889460 hasRelatedWork W4200625229 @default.
- W3084889460 hasRelatedWork W4210782677 @default.
- W3084889460 hasRelatedWork W4292448967 @default.
- W3084889460 hasRelatedWork W4296357423 @default.
- W3084889460 hasVolume "7" @default.
- W3084889460 isParatext "false" @default.
- W3084889460 isRetracted "false" @default.
- W3084889460 magId "3084889460" @default.
- W3084889460 workType "article" @default.