Matches in SemOpenAlex for { <https://semopenalex.org/work/W3084893658> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W3084893658 endingPage "106958" @default.
- W3084893658 startingPage "106958" @default.
- W3084893658 abstract "Skin cutaneous melanoma (SKCM) accounts for over 75% of skin cancer-related deaths each year. EAF2, as a member of EAF family, has been found in several cancers, however, the role of EAF2 in SKCM is rarely studied. In this study, we utilized multiple bioinformatics tools to systematically analyze the expression of EAF family and investigate the prognostic value of EAF2 in melanoma. We found both transcriptional and proteomics expression expressions of EAF2 were elevated in SKCM. Survival analysis and ROC curves showed significant diagnostic and prognostic ability of EAF2. Importantly, EAF2 expression was closely associated with the immune-infiltrating levels of B cells, CD4+ T, CD8+ T, neutrophils, macrophages and dendritic cells. Co-expression analysis showed EAF2 has a strong positive correlation with CD19, implying they may be functional partners in the immune response of SKCM. In summary, our study is the first to reveal that increased expression of EAF2 is significantly correlated with tumor progression and better prognosis in SKCM patients. The role of EAF2 in SKCM demonstrated that it might be a potential and promising biomarker for the diagnosis and prediction of prognosis in patients with SKCM." @default.
- W3084893658 created "2020-09-21" @default.
- W3084893658 creator A5005544676 @default.
- W3084893658 creator A5058059091 @default.
- W3084893658 date "2020-11-01" @default.
- W3084893658 modified "2023-10-18" @default.
- W3084893658 title "Systematic expression analysis of EAF family reveals the importance of EAF2 in melanoma" @default.
- W3084893658 cites W1784799388 @default.
- W3084893658 cites W1977918192 @default.
- W3084893658 cites W1986553481 @default.
- W3084893658 cites W1987951406 @default.
- W3084893658 cites W2020543365 @default.
- W3084893658 cites W2037216960 @default.
- W3084893658 cites W2068289276 @default.
- W3084893658 cites W2085893484 @default.
- W3084893658 cites W2097795961 @default.
- W3084893658 cites W2105924489 @default.
- W3084893658 cites W2130410032 @default.
- W3084893658 cites W2139876169 @default.
- W3084893658 cites W2149441684 @default.
- W3084893658 cites W2155142785 @default.
- W3084893658 cites W2160478953 @default.
- W3084893658 cites W2171030481 @default.
- W3084893658 cites W2281978300 @default.
- W3084893658 cites W2330451744 @default.
- W3084893658 cites W2336025940 @default.
- W3084893658 cites W2528526203 @default.
- W3084893658 cites W2531696307 @default.
- W3084893658 cites W2553276602 @default.
- W3084893658 cites W2558715006 @default.
- W3084893658 cites W2607129810 @default.
- W3084893658 cites W2758642703 @default.
- W3084893658 cites W2765224588 @default.
- W3084893658 cites W2769436242 @default.
- W3084893658 cites W2883265395 @default.
- W3084893658 cites W2895047375 @default.
- W3084893658 cites W2910806811 @default.
- W3084893658 cites W2937441321 @default.
- W3084893658 cites W2949891038 @default.
- W3084893658 cites W2986925253 @default.
- W3084893658 cites W4211223138 @default.
- W3084893658 cites W4253483740 @default.
- W3084893658 doi "https://doi.org/10.1016/j.intimp.2020.106958" @default.
- W3084893658 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33182068" @default.
- W3084893658 hasPublicationYear "2020" @default.
- W3084893658 type Work @default.
- W3084893658 sameAs 3084893658 @default.
- W3084893658 citedByCount "1" @default.
- W3084893658 countsByYear W30848936582023 @default.
- W3084893658 crossrefType "journal-article" @default.
- W3084893658 hasAuthorship W3084893658A5005544676 @default.
- W3084893658 hasAuthorship W3084893658A5058059091 @default.
- W3084893658 hasConcept C143998085 @default.
- W3084893658 hasConcept C203014093 @default.
- W3084893658 hasConcept C2781197716 @default.
- W3084893658 hasConcept C54355233 @default.
- W3084893658 hasConcept C71924100 @default.
- W3084893658 hasConcept C86803240 @default.
- W3084893658 hasConcept C8891405 @default.
- W3084893658 hasConceptScore W3084893658C143998085 @default.
- W3084893658 hasConceptScore W3084893658C203014093 @default.
- W3084893658 hasConceptScore W3084893658C2781197716 @default.
- W3084893658 hasConceptScore W3084893658C54355233 @default.
- W3084893658 hasConceptScore W3084893658C71924100 @default.
- W3084893658 hasConceptScore W3084893658C86803240 @default.
- W3084893658 hasConceptScore W3084893658C8891405 @default.
- W3084893658 hasLocation W30848936581 @default.
- W3084893658 hasOpenAccess W3084893658 @default.
- W3084893658 hasPrimaryLocation W30848936581 @default.
- W3084893658 hasRelatedWork W2050283198 @default.
- W3084893658 hasRelatedWork W2056075233 @default.
- W3084893658 hasRelatedWork W2056385328 @default.
- W3084893658 hasRelatedWork W2220102944 @default.
- W3084893658 hasRelatedWork W2577548098 @default.
- W3084893658 hasRelatedWork W3007075535 @default.
- W3084893658 hasRelatedWork W3031852375 @default.
- W3084893658 hasRelatedWork W3112940496 @default.
- W3084893658 hasRelatedWork W3187326853 @default.
- W3084893658 hasRelatedWork W4241494942 @default.
- W3084893658 hasVolume "88" @default.
- W3084893658 isParatext "false" @default.
- W3084893658 isRetracted "false" @default.
- W3084893658 magId "3084893658" @default.
- W3084893658 workType "article" @default.