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- W3084986334 abstract "Ankle sprain is one of the most common injuries for which patients frequently pursue complementary and alternative medicine instead of conventional medicine. The objective of this study was to evaluate the cost-effectiveness of herbal medicine therapy, Dangguixu-san, in patients with ankle sprains. Patients at the age of 19 years or older with Grade I to II lateral ankle sprains within 72 hours were eligible for this study. Patients were assigned to receive either acupuncture alone (control) or acupuncture in combination with Dangguixu-san (intervention) every day for one week with a follow-up period of additional 26 weeks. Treatment effectiveness was assessed using quality-adjusted life years (QALYs) at the end of the follow-up period. QALYs were calculated using the quality weights based on the EQ-5D. A decision tree model was constructed with treatment success defined as the Foot and Ankle Outcome Score (FAOS) of 75% or greater. The cost-effectiveness analysis was performed using a restricted societal perspective by including direct medical and non-medical costs. Overall, 46 patients were included and assigned to each group at a 1:1 ratio. Baseline characteristics of patients in each group were comparable (p > 0.05). The incremental QALY and cost in the intervention group was -0.008 (0.795 vs. 0.803 QALY) and 38,731 Korean Won (215,594 vs. 176,863 Korean Won), respectively, resulting in the incremental cost-effectiveness ratio (ICER) of -9,265,656 Korean Won/QALY. In conclusion, our analysis showed Dangguixu-san adjunctive treatment to acupuncture was dominated by acupuncture alone over one week of therapy in patients with mild to moderate lateral ankle sprains. Compared to acupuncture monotherapy, adjunctive therapy with Dangguixu-san in addition to acupuncture may not be cost-effective for the treatment of mild to moderate lateral ankle sprains." @default.
- W3084986334 created "2020-09-21" @default.
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- W3084986334 date "2020-09-01" @default.
- W3084986334 modified "2023-10-01" @default.
- W3084986334 title "PAM4 Cost-Effectiveness of Dangguixu-SAN for Patients with Mild to Moderate Ankle Sprain" @default.
- W3084986334 doi "https://doi.org/10.1016/j.vhri.2020.07.005" @default.
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