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- W3085003497 abstract "<h3>BACKGROUND AND PURPOSE:</h3> While third ventricular colloid cysts may present as an incidental finding, they also harbor the potential to cause ventricular obstruction and sudden death. Herein we analyze the relationship between imaging appearance and the risk of obstructive ventriculomegaly. <h3>MATERIALS AND METHODS:</h3> This is a retrospective review of the MR imaging appearance of 64 patients with colloid cysts, 46 of whom also had a CT scan, obtained by a tertiary hospital imaging report data base search over a 10-year period. Cysts were categorized by appearance on T2-FLAIR and correlated with patient age, cyst size, and the risk of obstructive ventriculomegaly. Histopathologic correlation was available for 28 cases. <h3>RESULTS:</h3> The 64-patient cohort was 52% female, median age 50 years (range 10 to 99 years). Cysts hyperintense on T2-FLAIR (53.1%) were larger (<i>P</i> <.001), occurred in younger patients (<i>P</i> = .01), and had a higher risk of obstructive ventriculomegaly than homogeneously hypointense cysts (relative risk 6.18, 95% CI [2.04, 18.67]). Three patterns of T2 hyperintensity were identified: homogeneously hyperintense, hyperintense rim, and cysts with “dot sign.” Although “dot sign” cysts were larger (<i>P</i> < .001), there was no significant difference in patient age or the risk of ventricular obstruction among T2 hyperintense cysts. Cyst wall histopathology did not vary with imaging appearance. <h3>CONCLUSIONS:</h3> Hyperintensity on T2-FLAIR, whether homogeneous, rim, or “dot sign,” is associated with larger cyst size and younger patient age, and is an imaging risk factor for obstructive ventriculomegaly. The hyperintense rim does not represent a thickened cyst wall." @default.
- W3085003497 created "2020-09-21" @default.
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- W3085003497 date "2020-09-10" @default.
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- W3085003497 title "The Variable Appearance of Third Ventricular Colloid Cysts: Correlation with Histopathology and the Risk of Obstructive Ventriculomegaly" @default.
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- W3085003497 doi "https://doi.org/10.3174/ajnr.a6722" @default.
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