Matches in SemOpenAlex for { <https://semopenalex.org/work/W3085304895> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W3085304895 endingPage "263" @default.
- W3085304895 startingPage "257" @default.
- W3085304895 abstract "Abstract In female breast cancer (BC), elastosis is strongly related to estrogen receptor alpha (ERα) expression. Male breast cancers almost invariably express ERα; so, the aim of this study was to investigate elastosis frequency in invasive male BC as well as clinicopathological correlations, in comparison with females. A total of 177 male BC cases and 135 female BC cases were included, all ERα-positive and invasive carcinoma of no special type. Elastosis on H&E-stained slides was scored in a four-tiered system as elastosis grade (EG) 0 (no elastosis) to EG3 (high amount of elastosis). EG scores in male BC were correlated to histopathological characteristics and overall surviva and compared with female BC EG scores. Male BC showed some degree of elastosis in 26/117 cases (22.2%) with none showing EG3, while female BC cases showed elastosis in 89/135 cases (65.9%) with 21.5% showing EG3 ( p < 0.001). This difference retained its significance in multivariate logistic regression. In male BC cases, no significant correlations were found between the amount of elastosis and age, grade, mitotic activity index, and PgR. In addition, no significant prognostic value of elastosis was seen. In conclusion, despite high ERα expression, male BC showed significantly less elastosis than female BC. Elastosis did not show clinicopathological correlations or prognostic value. Therefore, elastosis seems to be a less useful ERα tissue biomarker with less clinical significance in male BC compared with females, pointing towards important BC sex differences." @default.
- W3085304895 created "2020-09-21" @default.
- W3085304895 creator A5012677742 @default.
- W3085304895 creator A5040594661 @default.
- W3085304895 creator A5059199132 @default.
- W3085304895 creator A5064243944 @default.
- W3085304895 date "2020-09-15" @default.
- W3085304895 modified "2023-09-25" @default.
- W3085304895 title "Elastosis in ERα-positive male breast cancer" @default.
- W3085304895 cites W1488814076 @default.
- W3085304895 cites W1855871243 @default.
- W3085304895 cites W1997545849 @default.
- W3085304895 cites W2010871781 @default.
- W3085304895 cites W2024705563 @default.
- W3085304895 cites W2027610513 @default.
- W3085304895 cites W2035674296 @default.
- W3085304895 cites W2036750803 @default.
- W3085304895 cites W2058225402 @default.
- W3085304895 cites W2079741175 @default.
- W3085304895 cites W2088146122 @default.
- W3085304895 cites W2101979288 @default.
- W3085304895 cites W2112403300 @default.
- W3085304895 cites W2115686703 @default.
- W3085304895 cites W2130067006 @default.
- W3085304895 cites W2141926802 @default.
- W3085304895 cites W2146275594 @default.
- W3085304895 cites W2309323726 @default.
- W3085304895 cites W2419414214 @default.
- W3085304895 cites W2592908133 @default.
- W3085304895 cites W2603868227 @default.
- W3085304895 cites W2766828098 @default.
- W3085304895 cites W2911188335 @default.
- W3085304895 doi "https://doi.org/10.1007/s00428-020-02920-7" @default.
- W3085304895 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7969537" @default.
- W3085304895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32929565" @default.
- W3085304895 hasPublicationYear "2020" @default.
- W3085304895 type Work @default.
- W3085304895 sameAs 3085304895 @default.
- W3085304895 citedByCount "2" @default.
- W3085304895 countsByYear W30853048952021 @default.
- W3085304895 countsByYear W30853048952023 @default.
- W3085304895 crossrefType "journal-article" @default.
- W3085304895 hasAuthorship W3085304895A5012677742 @default.
- W3085304895 hasAuthorship W3085304895A5040594661 @default.
- W3085304895 hasAuthorship W3085304895A5059199132 @default.
- W3085304895 hasAuthorship W3085304895A5064243944 @default.
- W3085304895 hasBestOaLocation W30853048951 @default.
- W3085304895 hasConcept C121608353 @default.
- W3085304895 hasConcept C126322002 @default.
- W3085304895 hasConcept C142724271 @default.
- W3085304895 hasConcept C172313692 @default.
- W3085304895 hasConcept C204232928 @default.
- W3085304895 hasConcept C2777164284 @default.
- W3085304895 hasConcept C2777396416 @default.
- W3085304895 hasConcept C2781197716 @default.
- W3085304895 hasConcept C530470458 @default.
- W3085304895 hasConcept C55493867 @default.
- W3085304895 hasConcept C71924100 @default.
- W3085304895 hasConcept C84606932 @default.
- W3085304895 hasConcept C86803240 @default.
- W3085304895 hasConceptScore W3085304895C121608353 @default.
- W3085304895 hasConceptScore W3085304895C126322002 @default.
- W3085304895 hasConceptScore W3085304895C142724271 @default.
- W3085304895 hasConceptScore W3085304895C172313692 @default.
- W3085304895 hasConceptScore W3085304895C204232928 @default.
- W3085304895 hasConceptScore W3085304895C2777164284 @default.
- W3085304895 hasConceptScore W3085304895C2777396416 @default.
- W3085304895 hasConceptScore W3085304895C2781197716 @default.
- W3085304895 hasConceptScore W3085304895C530470458 @default.
- W3085304895 hasConceptScore W3085304895C55493867 @default.
- W3085304895 hasConceptScore W3085304895C71924100 @default.
- W3085304895 hasConceptScore W3085304895C84606932 @default.
- W3085304895 hasConceptScore W3085304895C86803240 @default.
- W3085304895 hasIssue "2" @default.
- W3085304895 hasLocation W30853048951 @default.
- W3085304895 hasLocation W30853048952 @default.
- W3085304895 hasLocation W30853048953 @default.
- W3085304895 hasOpenAccess W3085304895 @default.
- W3085304895 hasPrimaryLocation W30853048951 @default.
- W3085304895 hasRelatedWork W1970614368 @default.
- W3085304895 hasRelatedWork W2009089225 @default.
- W3085304895 hasRelatedWork W2009485082 @default.
- W3085304895 hasRelatedWork W2020508605 @default.
- W3085304895 hasRelatedWork W2038599327 @default.
- W3085304895 hasRelatedWork W2306478460 @default.
- W3085304895 hasRelatedWork W2373029859 @default.
- W3085304895 hasRelatedWork W3118911461 @default.
- W3085304895 hasRelatedWork W333594285 @default.
- W3085304895 hasRelatedWork W4286462803 @default.
- W3085304895 hasVolume "478" @default.
- W3085304895 isParatext "false" @default.
- W3085304895 isRetracted "false" @default.
- W3085304895 magId "3085304895" @default.
- W3085304895 workType "article" @default.