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- W3085323290 abstract "Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and has emerged as a serious public health challenge. About 20% of NAFLD patients may have low titres (<1:320) of antinuclear antibodies (ANA). However, we describe a patient with NAFLD whose ANA titre was high (>1:320) on presentation. After 3 months of diet, exercise and vitamin E supplementation, the patient was symptomatically better but her ANA titre had increased (>1:640). Her liver biopsy showed features of NAFLD with minimal fibrosis. High-titre ANA (>1:320) positivity is rare. Our patient showed a progressive rise in ANA titre from >1:320 to >1:640 within 3 months even though she was improving and histology showed minimal fibrosis.Up to 30% of patients with non-alcoholic fatty liver disease (NAFLD) may have antinuclear antibodies (ANA).Low titre (<1:320) ANA positivity is not uncommon, but a high titre is rare.The ANA titre does not correlate with the histological grade of NAFLD." @default.
- W3085323290 created "2020-09-21" @default.
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- W3085323290 date "2020-06-08" @default.
- W3085323290 modified "2023-09-23" @default.
- W3085323290 title "High-Titre ANA Positivity in NAFLD: An Uncommon Presentation of a Common Disease" @default.
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- W3085323290 doi "https://doi.org/10.12890/2020_001714" @default.
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