Matches in SemOpenAlex for { <https://semopenalex.org/work/W3085536377> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3085536377 endingPage "9234" @default.
- W3085536377 startingPage "9225" @default.
- W3085536377 abstract "Colorectal neoplasia differentially expressed (CRNDE) was reported to promote carcinogenesis in several cancers. However, the role of CRNDE in glioblastoma multiforme (GBM) needs to be further explored.CRNDE expression levels in GBM tissues and cells were explored using real-time quantitative PCR at first. Effects of CRNDE on GBM cell behaviors were detected by conducting in vitro experiments. Interactions of CRNDE, microRNA-337-3p (miR-337-3p), and ELMO domain containing 2 (ELMOD2) were verified by bioinformatics analysis tools and dual-luciferase reporter assay. Expression correlations of CRNDE and ELMOD2 in GBM tissues were analyzed at GEPIA website.CRNDE expression was upregulated in GBM tissues and cells compared with normal counterparts. CRDNE knockdown inhibits proliferation and migration, but promotes apoptosis in GBM cell, while CRNDE overexpression caused opposite effects. Mechanisms exploration indicated CRNDE serves as sponge of miR-337-3p to upregulate ELMOD2 expression. Furthermore, we showed CRNDE and ELMOD2 were positively correlated in GBM tissues.In conclusion, our study highlighted the importance of CRNDE/miR-337-3p/ELMOD2 axis in GBM progression and offered novel strategies for GBM treatment." @default.
- W3085536377 created "2020-09-21" @default.
- W3085536377 creator A5032538286 @default.
- W3085536377 creator A5063531299 @default.
- W3085536377 creator A5088866259 @default.
- W3085536377 creator A5090405267 @default.
- W3085536377 date "2020-09-01" @default.
- W3085536377 modified "2023-09-27" @default.
- W3085536377 title "<p>lncRNA CRNDE is Upregulated in Glioblastoma Multiforme and Facilitates Cancer Progression Through Targeting miR-337-3p and ELMOD2 Axis</p>" @default.
- W3085536377 cites W2087377443 @default.
- W3085536377 cites W2091161969 @default.
- W3085536377 cites W2107277218 @default.
- W3085536377 cites W2148977460 @default.
- W3085536377 cites W2149527725 @default.
- W3085536377 cites W2161590434 @default.
- W3085536377 cites W2166798417 @default.
- W3085536377 cites W2603374842 @default.
- W3085536377 cites W2760873274 @default.
- W3085536377 cites W2892745211 @default.
- W3085536377 cites W2893777382 @default.
- W3085536377 cites W2894257218 @default.
- W3085536377 cites W2903644661 @default.
- W3085536377 cites W2921793557 @default.
- W3085536377 cites W2945233193 @default.
- W3085536377 cites W2950611460 @default.
- W3085536377 cites W2980974593 @default.
- W3085536377 cites W2995249273 @default.
- W3085536377 cites W2997579060 @default.
- W3085536377 cites W4245392732 @default.
- W3085536377 cites W1964184380 @default.
- W3085536377 doi "https://doi.org/10.2147/ott.s249887" @default.
- W3085536377 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7502397" @default.
- W3085536377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32982309" @default.
- W3085536377 hasPublicationYear "2020" @default.
- W3085536377 type Work @default.
- W3085536377 sameAs 3085536377 @default.
- W3085536377 citedByCount "5" @default.
- W3085536377 countsByYear W30855363772020 @default.
- W3085536377 countsByYear W30855363772021 @default.
- W3085536377 countsByYear W30855363772022 @default.
- W3085536377 crossrefType "journal-article" @default.
- W3085536377 hasAuthorship W3085536377A5032538286 @default.
- W3085536377 hasAuthorship W3085536377A5063531299 @default.
- W3085536377 hasAuthorship W3085536377A5088866259 @default.
- W3085536377 hasAuthorship W3085536377A5090405267 @default.
- W3085536377 hasBestOaLocation W30855363771 @default.
- W3085536377 hasConcept C104317684 @default.
- W3085536377 hasConcept C121608353 @default.
- W3085536377 hasConcept C126322002 @default.
- W3085536377 hasConcept C127561419 @default.
- W3085536377 hasConcept C128473837 @default.
- W3085536377 hasConcept C145059251 @default.
- W3085536377 hasConcept C173396325 @default.
- W3085536377 hasConcept C190283241 @default.
- W3085536377 hasConcept C2776194525 @default.
- W3085536377 hasConcept C502942594 @default.
- W3085536377 hasConcept C54355233 @default.
- W3085536377 hasConcept C555283112 @default.
- W3085536377 hasConcept C62112901 @default.
- W3085536377 hasConcept C71924100 @default.
- W3085536377 hasConcept C86803240 @default.
- W3085536377 hasConceptScore W3085536377C104317684 @default.
- W3085536377 hasConceptScore W3085536377C121608353 @default.
- W3085536377 hasConceptScore W3085536377C126322002 @default.
- W3085536377 hasConceptScore W3085536377C127561419 @default.
- W3085536377 hasConceptScore W3085536377C128473837 @default.
- W3085536377 hasConceptScore W3085536377C145059251 @default.
- W3085536377 hasConceptScore W3085536377C173396325 @default.
- W3085536377 hasConceptScore W3085536377C190283241 @default.
- W3085536377 hasConceptScore W3085536377C2776194525 @default.
- W3085536377 hasConceptScore W3085536377C502942594 @default.
- W3085536377 hasConceptScore W3085536377C54355233 @default.
- W3085536377 hasConceptScore W3085536377C555283112 @default.
- W3085536377 hasConceptScore W3085536377C62112901 @default.
- W3085536377 hasConceptScore W3085536377C71924100 @default.
- W3085536377 hasConceptScore W3085536377C86803240 @default.
- W3085536377 hasLocation W30855363771 @default.
- W3085536377 hasLocation W30855363772 @default.
- W3085536377 hasLocation W30855363773 @default.
- W3085536377 hasOpenAccess W3085536377 @default.
- W3085536377 hasPrimaryLocation W30855363771 @default.
- W3085536377 hasRelatedWork W2095203455 @default.
- W3085536377 hasRelatedWork W2118293627 @default.
- W3085536377 hasRelatedWork W2303046684 @default.
- W3085536377 hasRelatedWork W2305853311 @default.
- W3085536377 hasRelatedWork W2466111283 @default.
- W3085536377 hasRelatedWork W2573992804 @default.
- W3085536377 hasRelatedWork W2943758353 @default.
- W3085536377 hasRelatedWork W4245617172 @default.
- W3085536377 hasRelatedWork W4282555464 @default.
- W3085536377 hasRelatedWork W4292329166 @default.
- W3085536377 hasVolume "Volume 13" @default.
- W3085536377 isParatext "false" @default.
- W3085536377 isRetracted "false" @default.
- W3085536377 magId "3085536377" @default.
- W3085536377 workType "article" @default.