Matches in SemOpenAlex for { <https://semopenalex.org/work/W3085754932> ?p ?o ?g. }
- W3085754932 endingPage "e3001" @default.
- W3085754932 startingPage "e2988" @default.
- W3085754932 abstract "Objective To test the hypothesis that patterns of semicircular canal (SCC) and otolith impairment in unilateral vestibular loss depend on the underlying disorders, we analyzed peripheral-vestibular function of all 5 vestibular sensors. Methods For this retrospective case series, we screened the hospital video-head-impulse test database (n = 4,983) for patients with unilaterally impaired SCC function who also received ocular vestibular-evoked myogenic potentials and cervical vestibular-evoked myogenic potentials (n = 302). Frequency of impairment of vestibular end organs (horizontal/anterior/posterior SCC, utriculus/sacculus) was analyzed with hierarchical cluster analysis and correlated with the underlying etiology. Results Acute vestibular neuropathy (AVN) (37.4%, 113 of 302), vestibular schwannoma (18.2%, 55 of 302), and acute cochleovestibular neuropathy (6.6%, 20 of 302) were most frequent. Horizontal SCC impairment (87.4%, 264 of 302) was more frequent ( p < 0.001) than posterior (47.4%, 143 of 302) and anterior (37.8%, 114 of 302) SCC impairment. Utricular damage (58%, 175 of 302) was noted more often ( p = 0.003) than saccular impairment (32%, 98 of 302). On average, 2.6 (95% confidence interval 2.48–2.78) vestibular sensors were deficient, with higher numbers ( p ≤ 0.017) for acute cochleovestibular neuropathy and vestibular schwannoma than for AVN, Menière disease, and episodic vestibular syndrome. In hierarchical cluster analysis, early mergers (posterior SCC/sacculus; anterior SCC/utriculus) pointed to closer pathophysiologic association of these sensors, whereas the late merger of the horizontal canal indicated a more distinct state. Conclusions While the extent and pattern of vestibular impairment critically depended on the underlying disorder, more limited damage in AVN and Menière disease was noted, emphasizing the individual range of loss of function and the value of vestibular mapping. Likely, both the anatomic properties of the different vestibular end organs and their vulnerability to external factors contribute to the relative sparing of the vertical canals and the sacculus." @default.
- W3085754932 created "2020-09-21" @default.
- W3085754932 creator A5014748846 @default.
- W3085754932 creator A5035868288 @default.
- W3085754932 creator A5067842871 @default.
- W3085754932 creator A5087790807 @default.
- W3085754932 date "2020-09-10" @default.
- W3085754932 modified "2023-10-17" @default.
- W3085754932 title "Vestibular mapping in patients with unilateral peripheral-vestibular deficits" @default.
- W3085754932 cites W1492410488 @default.
- W3085754932 cites W1521287996 @default.
- W3085754932 cites W1775737973 @default.
- W3085754932 cites W1968405946 @default.
- W3085754932 cites W2010063889 @default.
- W3085754932 cites W2011265479 @default.
- W3085754932 cites W2015910279 @default.
- W3085754932 cites W2016931939 @default.
- W3085754932 cites W2022145290 @default.
- W3085754932 cites W2024351788 @default.
- W3085754932 cites W2035196829 @default.
- W3085754932 cites W2035998163 @default.
- W3085754932 cites W2053154970 @default.
- W3085754932 cites W2062251857 @default.
- W3085754932 cites W2063493753 @default.
- W3085754932 cites W2064941460 @default.
- W3085754932 cites W2067640614 @default.
- W3085754932 cites W2069247400 @default.
- W3085754932 cites W2075421261 @default.
- W3085754932 cites W2089838408 @default.
- W3085754932 cites W2102612030 @default.
- W3085754932 cites W2115901982 @default.
- W3085754932 cites W2140541004 @default.
- W3085754932 cites W2141624098 @default.
- W3085754932 cites W2178160384 @default.
- W3085754932 cites W2256410958 @default.
- W3085754932 cites W2325054331 @default.
- W3085754932 cites W2328659924 @default.
- W3085754932 cites W2402737934 @default.
- W3085754932 cites W2415461190 @default.
- W3085754932 cites W2473548186 @default.
- W3085754932 cites W2474153063 @default.
- W3085754932 cites W2515667729 @default.
- W3085754932 cites W2526531673 @default.
- W3085754932 cites W2559809531 @default.
- W3085754932 cites W2582397968 @default.
- W3085754932 cites W2583665902 @default.
- W3085754932 cites W2608429579 @default.
- W3085754932 cites W2614488200 @default.
- W3085754932 cites W2617289580 @default.
- W3085754932 cites W2776892961 @default.
- W3085754932 cites W2792225247 @default.
- W3085754932 cites W2903393846 @default.
- W3085754932 cites W2915886874 @default.
- W3085754932 cites W2918721141 @default.
- W3085754932 cites W2936848617 @default.
- W3085754932 cites W2977877095 @default.
- W3085754932 cites W4293769421 @default.
- W3085754932 cites W4294215472 @default.
- W3085754932 doi "https://doi.org/10.1212/wnl.0000000000010812" @default.
- W3085754932 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32913014" @default.
- W3085754932 hasPublicationYear "2020" @default.
- W3085754932 type Work @default.
- W3085754932 sameAs 3085754932 @default.
- W3085754932 citedByCount "14" @default.
- W3085754932 countsByYear W30857549322021 @default.
- W3085754932 countsByYear W30857549322022 @default.
- W3085754932 countsByYear W30857549322023 @default.
- W3085754932 crossrefType "journal-article" @default.
- W3085754932 hasAuthorship W3085754932A5014748846 @default.
- W3085754932 hasAuthorship W3085754932A5035868288 @default.
- W3085754932 hasAuthorship W3085754932A5067842871 @default.
- W3085754932 hasAuthorship W3085754932A5087790807 @default.
- W3085754932 hasBestOaLocation W30857549322 @default.
- W3085754932 hasConcept C190041318 @default.
- W3085754932 hasConcept C2776837582 @default.
- W3085754932 hasConcept C2777340575 @default.
- W3085754932 hasConcept C2778039178 @default.
- W3085754932 hasConcept C2779868778 @default.
- W3085754932 hasConcept C2910076437 @default.
- W3085754932 hasConcept C548259974 @default.
- W3085754932 hasConcept C71924100 @default.
- W3085754932 hasConceptScore W3085754932C190041318 @default.
- W3085754932 hasConceptScore W3085754932C2776837582 @default.
- W3085754932 hasConceptScore W3085754932C2777340575 @default.
- W3085754932 hasConceptScore W3085754932C2778039178 @default.
- W3085754932 hasConceptScore W3085754932C2779868778 @default.
- W3085754932 hasConceptScore W3085754932C2910076437 @default.
- W3085754932 hasConceptScore W3085754932C548259974 @default.
- W3085754932 hasConceptScore W3085754932C71924100 @default.
- W3085754932 hasIssue "22" @default.
- W3085754932 hasLocation W30857549321 @default.
- W3085754932 hasLocation W30857549322 @default.
- W3085754932 hasOpenAccess W3085754932 @default.
- W3085754932 hasPrimaryLocation W30857549321 @default.
- W3085754932 hasRelatedWork W2009359314 @default.
- W3085754932 hasRelatedWork W2071719697 @default.
- W3085754932 hasRelatedWork W2133327662 @default.
- W3085754932 hasRelatedWork W2136929979 @default.