FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3085930813> ?p ?o ?g. }

• W3085930813 endingPage "2827" @default.
• W3085930813 startingPage "2827" @default.
• W3085930813 abstract "There is an association between food additive emulsifiers and the prevalence of Crohn’s disease. This study aimed to investigate: (i) the effect of different classes of emulsifiers on markers of intestinal inflammation in mice and (ii) the feasibility, nutritional adequacy and symptom impact of restricting all emulsifier classes in Crohn’s disease. Mice were exposed to different classes of emulsifiers (carboxymethycellose, polysorbate-80, soy lecithin, gum arabic) in drinking water for 12-weeks, after which markers of inflammation and metabolism were measured. A low emulsifier diet was developed to restrict all classes of emulsifiers and its feasibility measured over 14-days in 20 participants with stable Crohn’s disease. Crohn’s disease-related symptoms, disease control, body weight and composition, nutrient intake and food-related quality of life (QoL) were measured. All emulsifiers resulted in lower murine colonic length compared with control (mean 9.5 cm (SEM 0.20)), but this only reached significance for polysorbate-80 (8.2 cm (0.34), p = 0.024) and carboxymethylcellulose (8.0 cm (0.35), p = 0.013). All 20 participants completed the feasibility study. The frequency of consuming emulsifier-containing foods decreased by 94.6% (SD 10.3%). Food-related QoL improved between habitual (median 81.5 (IQR 25.0)) and low emulsifier diet (90.0 (24.0), p = 0.028). Crohn’s disease-related symptoms reduced (median 3.0 (IQR 5.3) vs. 1.4 (3.9), p = 0.006), and disease control scores improved (13.5 (IQR 6.0) vs. 15.5 (IQR 3.0), p = 0.026). A range of emulsifiers may influence intestinal inflammation in mice, and dietary restriction of emulsifiers is feasible. Trials investigating the efficacy of a low emulsifier diet in Crohn’s disease are warranted." @default.
• W3085930813 created "2020-09-21" @default.
• W3085930813 creator A5018718565 @default.
• W3085930813 creator A5019350885 @default.
• W3085930813 creator A5022833691 @default.
• W3085930813 creator A5046016414 @default.
• W3085930813 creator A5053643162 @default.
• W3085930813 creator A5055734737 @default.
• W3085930813 creator A5056049381 @default.
• W3085930813 date "2020-09-15" @default.
• W3085930813 modified "2023-10-18" @default.
• W3085930813 title "Emulsifiers Impact Colonic Length in Mice and Emulsifier Restriction is Feasible in People with Crohn’s Disease" @default.
• W3085930813 cites W1951893152 @default.
• W3085930813 cites W1969858925 @default.
• W3085930813 cites W1980047725 @default.
• W3085930813 cites W1990482544 @default.
• W3085930813 cites W1994905713 @default.
• W3085930813 cites W1996855281 @default.
• W3085930813 cites W2004608617 @default.
• W3085930813 cites W2032191478 @default.
• W3085930813 cites W2047981714 @default.
• W3085930813 cites W2074186820 @default.
• W3085930813 cites W2076548772 @default.
• W3085930813 cites W2081362293 @default.
• W3085930813 cites W2082494913 @default.
• W3085930813 cites W2097855460 @default.
• W3085930813 cites W2111211555 @default.
• W3085930813 cites W2127694169 @default.
• W3085930813 cites W2132296651 @default.
• W3085930813 cites W2133971099 @default.
• W3085930813 cites W2134657806 @default.
• W3085930813 cites W2135961894 @default.
• W3085930813 cites W2143342727 @default.
• W3085930813 cites W2161723853 @default.
• W3085930813 cites W2164966581 @default.
• W3085930813 cites W2250199585 @default.
• W3085930813 cites W2324893784 @default.
• W3085930813 cites W2400773242 @default.
• W3085930813 cites W2420961324 @default.
• W3085930813 cites W2531803186 @default.
• W3085930813 cites W2532466018 @default.
• W3085930813 cites W2586133422 @default.
• W3085930813 cites W2591969229 @default.
• W3085930813 cites W2599227191 @default.
• W3085930813 cites W2603041755 @default.
• W3085930813 cites W2604969316 @default.
• W3085930813 cites W2624184296 @default.
• W3085930813 cites W2671669090 @default.
• W3085930813 cites W2742822962 @default.
• W3085930813 cites W2748422233 @default.
• W3085930813 cites W2749270116 @default.
• W3085930813 cites W2765281497 @default.
• W3085930813 cites W2766046358 @default.
• W3085930813 cites W2803958193 @default.
• W3085930813 cites W2860795031 @default.
• W3085930813 cites W2902603283 @default.
• W3085930813 cites W2905266065 @default.
• W3085930813 cites W2920209172 @default.
• W3085930813 cites W2937883751 @default.
• W3085930813 cites W2940426001 @default.
• W3085930813 cites W2948015103 @default.
• W3085930813 cites W2948489634 @default.
• W3085930813 cites W2949629998 @default.
• W3085930813 cites W3015218178 @default.
• W3085930813 doi "https://doi.org/10.3390/nu12092827" @default.
• W3085930813 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7551245" @default.
• W3085930813 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32942699" @default.
• W3085930813 hasPublicationYear "2020" @default.
• W3085930813 type Work @default.
• W3085930813 sameAs 3085930813 @default.
• W3085930813 citedByCount "26" @default.
• W3085930813 countsByYear W30859308132020 @default.
• W3085930813 countsByYear W30859308132021 @default.
• W3085930813 countsByYear W30859308132022 @default.
• W3085930813 countsByYear W30859308132023 @default.
• W3085930813 crossrefType "journal-article" @default.
• W3085930813 hasAuthorship W3085930813A5018718565 @default.
• W3085930813 hasAuthorship W3085930813A5019350885 @default.
• W3085930813 hasAuthorship W3085930813A5022833691 @default.
• W3085930813 hasAuthorship W3085930813A5046016414 @default.
• W3085930813 hasAuthorship W3085930813A5053643162 @default.
• W3085930813 hasAuthorship W3085930813A5055734737 @default.
• W3085930813 hasAuthorship W3085930813A5056049381 @default.
• W3085930813 hasBestOaLocation W30859308131 @default.
• W3085930813 hasConcept C126322002 @default.
• W3085930813 hasConcept C2777897440 @default.
• W3085930813 hasConcept C2778260677 @default.
• W3085930813 hasConcept C2779134260 @default.
• W3085930813 hasConcept C2779280984 @default.
• W3085930813 hasConcept C2779564620 @default.
• W3085930813 hasConcept C2780054349 @default.
• W3085930813 hasConcept C31903555 @default.
• W3085930813 hasConcept C55493867 @default.
• W3085930813 hasConcept C58226133 @default.
• W3085930813 hasConcept C71924100 @default.
• W3085930813 hasConcept C86803240 @default.
• W3085930813 hasConcept C90924648 @default.
• W3085930813 hasConceptScore W3085930813C126322002 @default.

• next