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- W3086136973 abstract "Body composition analysis has emerged as a practical tool for predicting outcomes following pancreatic surgery. However, the impact of body composition disorders on clinically relevant postoperative pancreatic fistula (CR-POPF) remains inconclusive. The aim of this study was to review and analyse whether radiographically assessed body composition is predictive of CR-POPF. PubMed, MEDLINE, Web of Science, and the Cochrane Library databases were searched up to January 2020 to identify relevant studies. CR-POPF was defined according to the definition and grading system proposed by the International Study Group on Pancreatic Surgery (ISGPS). Pooled odds ratios (OR) for CR-POPF were calculated to evaluate the predictive values of radiographically assessed body composition. Fifteen studies published between 2008 and 2019 with a total of 3136 patients were included. There was a significant increase in the incidence of CR-POPF in patients with visceral obesity (OR 2.97, 95% CI 2.05–4.29, P < 0.00001) and sarcopenic obesity (OR 2.88, 95% CI 1.31–6.34, P = 0.009). Conversely, the impact of sarcopenia (OR 0.91, 95% CI 0.65–1.28, P = 0.59) and low muscle attenuation (MA) on CR-POPF did not reach statistical significance. Preoperative visceral obesity and sarcopenic obesity are more effective at predicting CR-POPF than decreased muscle quantity and quality. This finding may lead to appropriate management and early intervention of patients at risk of CR-POPF." @default.
- W3086136973 created "2020-09-21" @default.
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- W3086136973 date "2020-10-01" @default.
- W3086136973 modified "2023-09-23" @default.
- W3086136973 title "Prediction of clinically relevant pancreatic fistula after pancreatic surgery using preoperative CT scan: A systematic review and meta-analysis" @default.
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- W3086136973 doi "https://doi.org/10.1016/j.pan.2020.09.009" @default.
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