Matches in SemOpenAlex for { <https://semopenalex.org/work/W3086487277> ?p ?o ?g. }
- W3086487277 endingPage "104" @default.
- W3086487277 startingPage "91" @default.
- W3086487277 abstract "The presence of excessive reactive oxygen species (ROS) after injuries to the enthesis could lead to cellular oxidative damage, high inflammatory response, chronic inflammation, and limited fibrochondral inductivity, making tissue repair and functional recovery difficult. Here, a multifunctional silk fibroin nanofiber modified with polydopamine and kartogenin was designed and fabricated to not only effectively reduce inflammation by scavenging ROS in the early stage of the enthesis healing but also enhance fibrocartilage formation with fibrochondrogenic induction in the later stages. The in vitro results confirmed the antioxidant capability and the fibrochondral inductivity of the functionalized nanofibers. In vivo studies showed that the multifunctional nanofiber can significantly improve the integration of tendon-bone and accelerate the regeneration of interface tissue, resulting in an excellent biomechanical property. Thus, the incorporation of antioxidant and bio-active molecules into extracellular matrix-like biomaterials in interface tissue engineering provides an integrative approach that facilitates damaged tissue regeneration and functional recovery, thereby improving the clinical outcome of the engineered tissue." @default.
- W3086487277 created "2020-09-21" @default.
- W3086487277 creator A5009260752 @default.
- W3086487277 creator A5010946067 @default.
- W3086487277 creator A5014853349 @default.
- W3086487277 creator A5040886356 @default.
- W3086487277 creator A5041577536 @default.
- W3086487277 creator A5071773009 @default.
- W3086487277 creator A5073331778 @default.
- W3086487277 creator A5074176966 @default.
- W3086487277 creator A5084888732 @default.
- W3086487277 creator A5090751121 @default.
- W3086487277 date "2021-04-01" @default.
- W3086487277 modified "2023-10-16" @default.
- W3086487277 title "Multi-functionalized nanofibers with reactive oxygen species scavenging capability and fibrocartilage inductivity for tendon-bone integration" @default.
- W3086487277 cites W1486716069 @default.
- W3086487277 cites W1865976229 @default.
- W3086487277 cites W1970209371 @default.
- W3086487277 cites W1993727468 @default.
- W3086487277 cites W1999928739 @default.
- W3086487277 cites W2014603483 @default.
- W3086487277 cites W2026799007 @default.
- W3086487277 cites W2029774215 @default.
- W3086487277 cites W2031143428 @default.
- W3086487277 cites W2042990207 @default.
- W3086487277 cites W2069209273 @default.
- W3086487277 cites W2070995184 @default.
- W3086487277 cites W2071058847 @default.
- W3086487277 cites W2084141237 @default.
- W3086487277 cites W2087087192 @default.
- W3086487277 cites W2090106964 @default.
- W3086487277 cites W2092858957 @default.
- W3086487277 cites W2098092331 @default.
- W3086487277 cites W2102010479 @default.
- W3086487277 cites W2122180971 @default.
- W3086487277 cites W2124288159 @default.
- W3086487277 cites W2129938298 @default.
- W3086487277 cites W2134121503 @default.
- W3086487277 cites W2142801671 @default.
- W3086487277 cites W2153811118 @default.
- W3086487277 cites W2153997464 @default.
- W3086487277 cites W2172012214 @default.
- W3086487277 cites W2197923441 @default.
- W3086487277 cites W2322562148 @default.
- W3086487277 cites W2338603586 @default.
- W3086487277 cites W2566562918 @default.
- W3086487277 cites W2570385031 @default.
- W3086487277 cites W2582650077 @default.
- W3086487277 cites W2592099693 @default.
- W3086487277 cites W2608036794 @default.
- W3086487277 cites W2610551227 @default.
- W3086487277 cites W2636808498 @default.
- W3086487277 cites W2652296546 @default.
- W3086487277 cites W2740241656 @default.
- W3086487277 cites W2759533195 @default.
- W3086487277 cites W2771726897 @default.
- W3086487277 cites W2790090456 @default.
- W3086487277 cites W2790624515 @default.
- W3086487277 cites W2791939349 @default.
- W3086487277 cites W2810059531 @default.
- W3086487277 cites W2883552344 @default.
- W3086487277 cites W2899035137 @default.
- W3086487277 cites W2908713334 @default.
- W3086487277 cites W2916251492 @default.
- W3086487277 cites W2921012681 @default.
- W3086487277 cites W2977272968 @default.
- W3086487277 cites W4256150552 @default.
- W3086487277 doi "https://doi.org/10.1016/j.jmst.2020.09.006" @default.
- W3086487277 hasPublicationYear "2021" @default.
- W3086487277 type Work @default.
- W3086487277 sameAs 3086487277 @default.
- W3086487277 citedByCount "10" @default.
- W3086487277 countsByYear W30864872772021 @default.
- W3086487277 countsByYear W30864872772022 @default.
- W3086487277 countsByYear W30864872772023 @default.
- W3086487277 crossrefType "journal-article" @default.
- W3086487277 hasAuthorship W3086487277A5009260752 @default.
- W3086487277 hasAuthorship W3086487277A5010946067 @default.
- W3086487277 hasAuthorship W3086487277A5014853349 @default.
- W3086487277 hasAuthorship W3086487277A5040886356 @default.
- W3086487277 hasAuthorship W3086487277A5041577536 @default.
- W3086487277 hasAuthorship W3086487277A5071773009 @default.
- W3086487277 hasAuthorship W3086487277A5073331778 @default.
- W3086487277 hasAuthorship W3086487277A5074176966 @default.
- W3086487277 hasAuthorship W3086487277A5084888732 @default.
- W3086487277 hasAuthorship W3086487277A5090751121 @default.
- W3086487277 hasConcept C105702510 @default.
- W3086487277 hasConcept C122302759 @default.
- W3086487277 hasConcept C136229726 @default.
- W3086487277 hasConcept C142724271 @default.
- W3086487277 hasConcept C159985019 @default.
- W3086487277 hasConcept C171056886 @default.
- W3086487277 hasConcept C171250308 @default.
- W3086487277 hasConcept C174286582 @default.
- W3086487277 hasConcept C192562407 @default.
- W3086487277 hasConcept C204787440 @default.
- W3086487277 hasConcept C2776164576 @default.
- W3086487277 hasConcept C2780105995 @default.