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• W3086945144 endingPage "6720" @default.
• W3086945144 startingPage "6705" @default.
• W3086945144 abstract "Over the last decades, joint arthroplasty has become a successful treatment for joint disease. Nowadays, with a growing demand and increasingly younger and active patients accepting these approaches, orthopedic surgeons are seeking implants with improved mechanical behavior and longer life span. However, aseptic loosening as a result of wear debris from implants is considered to be the main cause of long-term implant failure. Previous studies have neatly illustrated the role of micrometric wear particles in the pathological mechanisms underlying aseptic loosening. Recent osteoimmunologic insights into aseptic loosening highlight the important and heretofore underrepresented contribution of nanometric orthopedic wear particles. The present review updates the characteristics of metallic and ceramic nanoparticles generated after prosthesis implantation and summarizes the current understanding of their hazardous effects on peri-prosthetic cells." @default.
• W3086945144 created "2020-09-21" @default.
• W3086945144 creator A5027039584 @default.
• W3086945144 creator A5030877015 @default.
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• W3086945144 creator A5070297739 @default.
• W3086945144 creator A5086266957 @default.
• W3086945144 date "2020-09-01" @default.
• W3086945144 modified "2023-10-14" @default.
• W3086945144 title "<p>Local Cellular Responses to Metallic and Ceramic Nanoparticles from Orthopedic Joint Arthroplasty Implants</p>" @default.
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