Matches in SemOpenAlex for { <https://semopenalex.org/work/W3087016145> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3087016145 abstract "AIMS The relationship between ferritin levels and survival in adult hemophagocytic lymphohistiocytosis (HLH) has been evaluated in previous studies. However, Admission-to-discharge percentage ferritin reduction (named as ferritin index) level in adult patients with HLH has never been evaluated to predict 6-month survival. METHODS The demographic, laboratory and clinical information of 102 newly diagnosed adult HLH patients were collected. Regression analysis, receiver operating curve and Kaplan-Meier curves were analysed to explore the performance of ferritin levels. RESULTS Ferritin index and discharge ferritin level were significantly different between survivour and non-survivour group (all P < .001). Ferritin index had the highest area under the curve (AUC) for predicting the survival (AUC = 0.802, P < .001) followed by discharge ferritin (AUC = 0.746, P < .001). Kaplan-Meier analysis showed a significant difference in survival according to optimum cutoff values of ferritin index ≥ 10.19% (P < .001) or discharge ferritin ≤ 1056.1 μg/L (P < .001). Multivariate analysis confirmed that ferritin index and discharge ferritin are independent predictors of 6-month survival (ferritin index: odds ratio (HR) 6.237, 95% confidence interval (CI) 2.075-18.774, P = .001; discharge ferritin: HR 6.024, 95% CI 1.894-19.231, P = .002). In addition, the combination of a ferritin index ≥ 10.19% and discharge ferritin ≤ 1056.1 μg/L had a significantly higher 6-month survival (P < .001). CONCLUSION Ferritin index is a better predictor of 6-month survival than admission and discharges ferritin levels in adult patients with HLH." @default.
- W3087016145 created "2020-09-25" @default.
- W3087016145 creator A5018785155 @default.
- W3087016145 creator A5024961418 @default.
- W3087016145 creator A5027336810 @default.
- W3087016145 creator A5066037312 @default.
- W3087016145 creator A5068996081 @default.
- W3087016145 date "2020-10-12" @default.
- W3087016145 modified "2023-10-18" @default.
- W3087016145 title "Ferritin index is a strong prognostic marker in adult hemophagocytic lymphohistiocytosis" @default.
- W3087016145 cites W1505641753 @default.
- W3087016145 cites W1652620147 @default.
- W3087016145 cites W1925777576 @default.
- W3087016145 cites W1964179232 @default.
- W3087016145 cites W2021347632 @default.
- W3087016145 cites W2055476027 @default.
- W3087016145 cites W2063048890 @default.
- W3087016145 cites W2068406703 @default.
- W3087016145 cites W2068646465 @default.
- W3087016145 cites W2087965932 @default.
- W3087016145 cites W2098626256 @default.
- W3087016145 cites W2153170511 @default.
- W3087016145 cites W2162251899 @default.
- W3087016145 cites W2430111446 @default.
- W3087016145 cites W2613332598 @default.
- W3087016145 cites W2766936218 @default.
- W3087016145 cites W2774435803 @default.
- W3087016145 cites W2958124371 @default.
- W3087016145 cites W2970701054 @default.
- W3087016145 cites W2975778618 @default.
- W3087016145 cites W3003540192 @default.
- W3087016145 cites W3011598043 @default.
- W3087016145 cites W3027205583 @default.
- W3087016145 doi "https://doi.org/10.1111/ijcp.13704" @default.
- W3087016145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32931059" @default.
- W3087016145 hasPublicationYear "2020" @default.
- W3087016145 type Work @default.
- W3087016145 sameAs 3087016145 @default.
- W3087016145 citedByCount "11" @default.
- W3087016145 countsByYear W30870161452022 @default.
- W3087016145 countsByYear W30870161452023 @default.
- W3087016145 crossrefType "journal-article" @default.
- W3087016145 hasAuthorship W3087016145A5018785155 @default.
- W3087016145 hasAuthorship W3087016145A5024961418 @default.
- W3087016145 hasAuthorship W3087016145A5027336810 @default.
- W3087016145 hasAuthorship W3087016145A5066037312 @default.
- W3087016145 hasAuthorship W3087016145A5068996081 @default.
- W3087016145 hasBestOaLocation W30870161451 @default.
- W3087016145 hasConcept C136764020 @default.
- W3087016145 hasConcept C142724271 @default.
- W3087016145 hasConcept C203014093 @default.
- W3087016145 hasConcept C2777382242 @default.
- W3087016145 hasConcept C2778319317 @default.
- W3087016145 hasConcept C2779079688 @default.
- W3087016145 hasConcept C2779134260 @default.
- W3087016145 hasConcept C41008148 @default.
- W3087016145 hasConcept C71924100 @default.
- W3087016145 hasConceptScore W3087016145C136764020 @default.
- W3087016145 hasConceptScore W3087016145C142724271 @default.
- W3087016145 hasConceptScore W3087016145C203014093 @default.
- W3087016145 hasConceptScore W3087016145C2777382242 @default.
- W3087016145 hasConceptScore W3087016145C2778319317 @default.
- W3087016145 hasConceptScore W3087016145C2779079688 @default.
- W3087016145 hasConceptScore W3087016145C2779134260 @default.
- W3087016145 hasConceptScore W3087016145C41008148 @default.
- W3087016145 hasConceptScore W3087016145C71924100 @default.
- W3087016145 hasIssue "3" @default.
- W3087016145 hasLocation W30870161451 @default.
- W3087016145 hasOpenAccess W3087016145 @default.
- W3087016145 hasPrimaryLocation W30870161451 @default.
- W3087016145 hasRelatedWork W1964179232 @default.
- W3087016145 hasRelatedWork W2051898696 @default.
- W3087016145 hasRelatedWork W2138205867 @default.
- W3087016145 hasRelatedWork W2362122205 @default.
- W3087016145 hasRelatedWork W2739735509 @default.
- W3087016145 hasRelatedWork W3023820785 @default.
- W3087016145 hasRelatedWork W3040599226 @default.
- W3087016145 hasRelatedWork W3087016145 @default.
- W3087016145 hasRelatedWork W3120308137 @default.
- W3087016145 hasRelatedWork W3133260551 @default.
- W3087016145 hasVolume "75" @default.
- W3087016145 isParatext "false" @default.
- W3087016145 isRetracted "false" @default.
- W3087016145 magId "3087016145" @default.
- W3087016145 workType "article" @default.