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• W3087070834 endingPage "106123" @default.
• W3087070834 startingPage "106123" @default.
• W3087070834 abstract "The findings of per- and polyfluoroalkyl substances (PFAS) in humans and the environment all over the world have raised concerns and public awareness for this group of man-made chemicals. In the last three decades, this led to different regulatory restrictions for specific PFAS as well as shifts in the production and usage of these substances. In this study, we analyzed the PFAS levels of 100 human blood plasma samples collected from 2009 to 2019 for the German Environmental Specimen Bank (ESB) to further elucidate the time course of exposure towards this substance group as shown by Schröter-Kermani et al., (2013) with samples from 1982 to 2010. A spectrum of 37 PFAS, including perfluorocarboxylic (PFCA) and –sulfonic acids (PFSA) as well as potential precursors and substitutes like ADONA, GenX or F-53B was analyzed by UHPLC coupled with high-resolution mass spectrometry. Validation was successful for 33 of the substances. The two legacy substances perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) were detected in every sample of the 2009–2019 dataset and showed the highest concentrations with ranges of 0.27–14.0 ng/mL and 1.21–14.1 ng/mL, respectively. A significant portion of total PFOS analytes was present as branched isomers (mean: 34 ± 7%). High detection frequencies of 95% and 82% were also found for perfluorohexane sulfonic acid (PFHxS) and perfluorononanoic acid (PFNA), respectively, but in lower concentrations (PFHxS: <LOQ – 4.62 ng/mL; PFNA: <LOQ – 3.66 ng/mL) than PFOA and PFOS. Besides other PFCA and PFSA only 8:2 fluorotelomer sulfonic acid (8:2 FtS) and N-methyl perfluorooctane sulfonamidoacetic acid were detected in very few samples. In combination with the previous results from 1982 to 2010, declining temporal trends were observed for all PFAS (PFOA, PFNA, PFHxS, and PFOS) frequently detected in the ESB samples. The results of this study indicate a decrease in human exposure to known PFAS in Germany over the last three decades and emphasize the importance of long-term human biomonitoring studies for investigating the effects of chemical regulation." @default.
• W3087070834 created "2020-09-25" @default.
• W3087070834 creator A5005736964 @default.
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• W3087070834 creator A5049352839 @default.
• W3087070834 date "2020-12-01" @default.
• W3087070834 modified "2023-10-17" @default.
• W3087070834 title "Human biomonitoring of per- and polyfluoroalkyl substances in German blood plasma samples from 1982 to 2019" @default.
• W3087070834 cites W1816790510 @default.
• W3087070834 cites W1966277022 @default.
• W3087070834 cites W1967920645 @default.
• W3087070834 cites W1971106859 @default.
• W3087070834 cites W1972074055 @default.
• W3087070834 cites W1972252649 @default.
• W3087070834 cites W1975712351 @default.
• W3087070834 cites W1982293068 @default.
• W3087070834 cites W1989064042 @default.
• W3087070834 cites W1993650845 @default.
• W3087070834 cites W1997592674 @default.
• W3087070834 cites W1999027093 @default.
• W3087070834 cites W2003400440 @default.
• W3087070834 cites W2008890169 @default.
• W3087070834 cites W2010495589 @default.
• W3087070834 cites W2019165840 @default.
• W3087070834 cites W2025159998 @default.
• W3087070834 cites W2029916104 @default.
• W3087070834 cites W2030183425 @default.
• W3087070834 cites W2030495254 @default.
• W3087070834 cites W2040001432 @default.
• W3087070834 cites W2044837675 @default.
• W3087070834 cites W2056819642 @default.
• W3087070834 cites W2057869914 @default.
• W3087070834 cites W2058922852 @default.
• W3087070834 cites W2062930348 @default.
• W3087070834 cites W2064562166 @default.
• W3087070834 cites W2067813964 @default.
• W3087070834 cites W2069217149 @default.
• W3087070834 cites W2083987580 @default.
• W3087070834 cites W2084435560 @default.
• W3087070834 cites W2085442777 @default.
• W3087070834 cites W2112558380 @default.
• W3087070834 cites W2128655175 @default.
• W3087070834 cites W2151989756 @default.
• W3087070834 cites W2153533007 @default.
• W3087070834 cites W2156625182 @default.
• W3087070834 cites W2196882830 @default.
• W3087070834 cites W2317101619 @default.
• W3087070834 cites W2318739473 @default.
• W3087070834 cites W2322472488 @default.
• W3087070834 cites W2335224112 @default.
• W3087070834 cites W2490629395 @default.
• W3087070834 cites W2528899831 @default.
• W3087070834 cites W2537858370 @default.
• W3087070834 cites W2542772104 @default.
• W3087070834 cites W2550628789 @default.
• W3087070834 cites W2558870407 @default.
• W3087070834 cites W2569767719 @default.
• W3087070834 cites W2571311620 @default.
• W3087070834 cites W2616208216 @default.
• W3087070834 cites W2621568371 @default.
• W3087070834 cites W2696100022 @default.
• W3087070834 cites W2753572084 @default.
• W3087070834 cites W2766331799 @default.
• W3087070834 cites W2775721539 @default.
• W3087070834 cites W2796003467 @default.
• W3087070834 cites W2799444013 @default.
• W3087070834 cites W2802762047 @default.
• W3087070834 cites W2809882610 @default.
• W3087070834 cites W2898521203 @default.
• W3087070834 cites W2903063066 @default.
• W3087070834 cites W2904612650 @default.
• W3087070834 cites W2908515602 @default.
• W3087070834 cites W2913872591 @default.
• W3087070834 cites W2914855384 @default.
• W3087070834 cites W2921313054 @default.
• W3087070834 cites W2954870180 @default.
• W3087070834 cites W2966730315 @default.
• W3087070834 cites W2981858891 @default.
• W3087070834 cites W2982726052 @default.
• W3087070834 cites W2985564152 @default.
• W3087070834 cites W3001721166 @default.
• W3087070834 cites W3006798469 @default.
• W3087070834 cites W3008469335 @default.
• W3087070834 cites W3012240676 @default.
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• W3087070834 doi "https://doi.org/10.1016/j.envint.2020.106123" @default.
• W3087070834 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32949877" @default.
• W3087070834 hasPublicationYear "2020" @default.
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