Matches in SemOpenAlex for { <https://semopenalex.org/work/W3087470870> ?p ?o ?g. }
- W3087470870 endingPage "805" @default.
- W3087470870 startingPage "795" @default.
- W3087470870 abstract "Cyclin-dependent kinases 4 and 6 (CDK4/6) along with their upstream/downstream components are pivotal regulators for the cell cycle progression. The dysfunction of CDK4/6 is the common feature and promoting factor in various cancer types. In-depth research on CDK4/6 inhibitors has afforded therapeutic agents, while new challenges and ideas are emerging concomitantly.This review focuses on patent publications related to CDK4/6 inhibitors which could be utilized for anti-cancer purposes during the period 2015-2019.The increasingly comprehensive and thorough understanding of CDK4/6 inhibitors facilitates them to break through the current limitations. Hence the utilization of CDK4/6 inhibitors for cancer therapy in the near future is likely to be performed in diverse forms and for distinct purposes. Selectivity over kinases is still crucial to new agent development but shall be prudently dealt with. The gradually revealing of resistance and adverse events proposed another issue that calls for new tackling strategies." @default.
- W3087470870 created "2020-09-25" @default.
- W3087470870 creator A5035976373 @default.
- W3087470870 creator A5065648379 @default.
- W3087470870 creator A5069321096 @default.
- W3087470870 creator A5069888386 @default.
- W3087470870 date "2020-09-30" @default.
- W3087470870 modified "2023-09-23" @default.
- W3087470870 title "Cyclin-dependent kinase 4/6 inhibitors for cancer therapy: a patent review (2015 – 2019)" @default.
- W3087470870 cites W1944091105 @default.
- W3087470870 cites W1964764225 @default.
- W3087470870 cites W2019956469 @default.
- W3087470870 cites W2034749721 @default.
- W3087470870 cites W2057272791 @default.
- W3087470870 cites W2089353165 @default.
- W3087470870 cites W2096039018 @default.
- W3087470870 cites W2118945879 @default.
- W3087470870 cites W2136158663 @default.
- W3087470870 cites W2137177885 @default.
- W3087470870 cites W2149131110 @default.
- W3087470870 cites W2155638473 @default.
- W3087470870 cites W2158080359 @default.
- W3087470870 cites W2209971370 @default.
- W3087470870 cites W2219817965 @default.
- W3087470870 cites W2297912447 @default.
- W3087470870 cites W2321710696 @default.
- W3087470870 cites W2369393864 @default.
- W3087470870 cites W2491062142 @default.
- W3087470870 cites W2508599517 @default.
- W3087470870 cites W2569340153 @default.
- W3087470870 cites W2581841075 @default.
- W3087470870 cites W2592223896 @default.
- W3087470870 cites W2625751604 @default.
- W3087470870 cites W2754274368 @default.
- W3087470870 cites W2756171891 @default.
- W3087470870 cites W2767870395 @default.
- W3087470870 cites W2767920323 @default.
- W3087470870 cites W2768722765 @default.
- W3087470870 cites W2775259666 @default.
- W3087470870 cites W2790167050 @default.
- W3087470870 cites W2793947925 @default.
- W3087470870 cites W2794460349 @default.
- W3087470870 cites W2795296107 @default.
- W3087470870 cites W2802098834 @default.
- W3087470870 cites W2891913333 @default.
- W3087470870 cites W2892006800 @default.
- W3087470870 cites W2892322996 @default.
- W3087470870 cites W2897660975 @default.
- W3087470870 cites W2898284988 @default.
- W3087470870 cites W2898919491 @default.
- W3087470870 cites W2902263717 @default.
- W3087470870 cites W2904387890 @default.
- W3087470870 cites W2916822761 @default.
- W3087470870 cites W2924113881 @default.
- W3087470870 cites W2936661052 @default.
- W3087470870 cites W2937360259 @default.
- W3087470870 cites W2944271257 @default.
- W3087470870 cites W2952777804 @default.
- W3087470870 cites W2954132938 @default.
- W3087470870 cites W2970349558 @default.
- W3087470870 cites W2977211443 @default.
- W3087470870 cites W2985866907 @default.
- W3087470870 doi "https://doi.org/10.1080/13543776.2020.1825686" @default.
- W3087470870 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32945222" @default.
- W3087470870 hasPublicationYear "2020" @default.
- W3087470870 type Work @default.
- W3087470870 sameAs 3087470870 @default.
- W3087470870 citedByCount "7" @default.
- W3087470870 countsByYear W30874708702021 @default.
- W3087470870 countsByYear W30874708702022 @default.
- W3087470870 crossrefType "journal-article" @default.
- W3087470870 hasAuthorship W3087470870A5035976373 @default.
- W3087470870 hasAuthorship W3087470870A5065648379 @default.
- W3087470870 hasAuthorship W3087470870A5069321096 @default.
- W3087470870 hasAuthorship W3087470870A5069888386 @default.
- W3087470870 hasConcept C121608353 @default.
- W3087470870 hasConcept C124320809 @default.
- W3087470870 hasConcept C126322002 @default.
- W3087470870 hasConcept C184235292 @default.
- W3087470870 hasConcept C29537977 @default.
- W3087470870 hasConcept C2994037739 @default.
- W3087470870 hasConcept C502942594 @default.
- W3087470870 hasConcept C60644358 @default.
- W3087470870 hasConcept C71924100 @default.
- W3087470870 hasConcept C86803240 @default.
- W3087470870 hasConcept C95444343 @default.
- W3087470870 hasConceptScore W3087470870C121608353 @default.
- W3087470870 hasConceptScore W3087470870C124320809 @default.
- W3087470870 hasConceptScore W3087470870C126322002 @default.
- W3087470870 hasConceptScore W3087470870C184235292 @default.
- W3087470870 hasConceptScore W3087470870C29537977 @default.
- W3087470870 hasConceptScore W3087470870C2994037739 @default.
- W3087470870 hasConceptScore W3087470870C502942594 @default.
- W3087470870 hasConceptScore W3087470870C60644358 @default.
- W3087470870 hasConceptScore W3087470870C71924100 @default.
- W3087470870 hasConceptScore W3087470870C86803240 @default.
- W3087470870 hasConceptScore W3087470870C95444343 @default.
- W3087470870 hasIssue "10" @default.