FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3087490605> ?p ?o ?g. }

• W3087490605 endingPage "2914" @default.
• W3087490605 startingPage "2904" @default.
• W3087490605 abstract "As we all know, pulmonary edema can be diagnosed by lung ultrasound (LUS), but how to accurately and quantitatively evaluate lung water content by ultrasound is a difficult problem that needs to be solved urgently. B-line assessment with LUS has recently been proposed as a reliable, noninvasive semiquantitative tool for evaluating extravascular lung water (EVLW). To date, however, there has been no easy quantitative method to evaluate EVLW by LUS.(1) To explore the feasibility of establishing a rabbit model with increased EVLW by injecting warm normal saline (NS) into the lungs via the endotracheal tube. (2) To establish a simple, accurate and clinically operable method for quantitative assessment of EVLW using LUS. (3) To develop LUS into a resource for guiding the clinical treatment of patients with increased EVLW.Forty-five New Zealand rabbits were randomized into nine groups (n = 5). After anesthesia, each group of rabbits was injected with different amounts of warm sterile NS (0 ml/kg, 2 ml/kg, 4 ml/kg, 6 ml/kg, 8 ml/kg, 10 ml/kg, 15 ml/kg, 20 ml/kg, 30 ml/kg) via the endotracheal tube. Each rabbit was examined by LUS before and after NS injection. At the same time, the spontaneous respiratory rate (RR, breaths per minute), heart rate (HR, bpm) and arterial blood gas (ABG) of the rabbits were recorded. Then, both lungs were dissected to obtain the wet and dry weight and conduct a complete histological examination.Injecting NS into the lungs through a tracheal tube can successfully establish a rabbit model with increased EVLW. The extent of EVLW increase is related to the volume of NS injected into the lungs. As the EVLW increases, three different types of B-lines can be seen in the LUS. When the NS injection volume is 2-6 ml/kg, comet-tail artifacts and B-lines are the main patterns found on LUS; as additional NS is injected into the lungs, the rabbits' RR gradually increases, while their HR gradually decreases, ABG remains normal or shows mild metabolic acidosis (MA). Confluent B-lines grow gradually but significantly, reaching a dominant position when the NS injection volume reaches 6-8 ml/kg and predominating almost entirely when the NS injection volume is 8-15 ml/kg; at that time, rabbits' RRs and HRs decrease sharply, and the ABG indicated type I respiratory failure (RF).Compact B-lines occur and predominate almost entirely when the NS injection volume reaches 10 ml/kg and 15-20 ml/kg, respectively. At that time, rabbits begin to enter cardiac and respiratory arrest, and ABG shows type II RF and MA.In this study, the establishment of an animal model with increased EVLW confirmed that different lung water content had corresponding manifestations in ultrasound and was associated with different degrees of clinical symptoms, and the study results can be used to guide clinical practice." @default.
• W3087490605 created "2020-09-25" @default.
• W3087490605 creator A5020139977 @default.
• W3087490605 creator A5030985805 @default.
• W3087490605 creator A5053619846 @default.
• W3087490605 creator A5077142667 @default.
• W3087490605 date "2020-09-16" @default.
• W3087490605 modified "2023-10-16" @default.
• W3087490605 title "Lung ultrasound to quantitatively evaluate extravascular lung water content and its clinical significance" @default.
• W3087490605 cites W1982115580 @default.
• W3087490605 cites W1986326104 @default.
• W3087490605 cites W1988079789 @default.
• W3087490605 cites W201276026 @default.
• W3087490605 cites W2022479952 @default.
• W3087490605 cites W2022941944 @default.
• W3087490605 cites W2023447167 @default.
• W3087490605 cites W2029525090 @default.
• W3087490605 cites W2029976897 @default.
• W3087490605 cites W2036861737 @default.
• W3087490605 cites W2041829536 @default.
• W3087490605 cites W2043362119 @default.
• W3087490605 cites W2043885886 @default.
• W3087490605 cites W2044295761 @default.
• W3087490605 cites W2057169895 @default.
• W3087490605 cites W2059372202 @default.
• W3087490605 cites W2061918187 @default.
• W3087490605 cites W2065770093 @default.
• W3087490605 cites W2085482820 @default.
• W3087490605 cites W2089368472 @default.
• W3087490605 cites W2095706419 @default.
• W3087490605 cites W2098163357 @default.
• W3087490605 cites W2132114460 @default.
• W3087490605 cites W2138197590 @default.
• W3087490605 cites W2143557911 @default.
• W3087490605 cites W2150835094 @default.
• W3087490605 cites W2154581887 @default.
• W3087490605 cites W2239299232 @default.
• W3087490605 cites W2296086700 @default.
• W3087490605 cites W2410908311 @default.
• W3087490605 cites W2490868668 @default.
• W3087490605 cites W2519891162 @default.
• W3087490605 cites W2579382756 @default.
• W3087490605 cites W2621410826 @default.
• W3087490605 cites W2746598451 @default.
• W3087490605 cites W276499480 @default.
• W3087490605 cites W2792056239 @default.
• W3087490605 cites W2920880416 @default.
• W3087490605 cites W2948339364 @default.
• W3087490605 cites W2985332465 @default.
• W3087490605 cites W4205247160 @default.
• W3087490605 doi "https://doi.org/10.1080/14767058.2020.1812057" @default.
• W3087490605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32938256" @default.
• W3087490605 hasPublicationYear "2020" @default.
• W3087490605 type Work @default.
• W3087490605 sameAs 3087490605 @default.
• W3087490605 citedByCount "2" @default.
• W3087490605 countsByYear W30874906052022 @default.
• W3087490605 crossrefType "journal-article" @default.
• W3087490605 hasAuthorship W3087490605A5020139977 @default.
• W3087490605 hasAuthorship W3087490605A5030985805 @default.
• W3087490605 hasAuthorship W3087490605A5053619846 @default.
• W3087490605 hasAuthorship W3087490605A5077142667 @default.
• W3087490605 hasBestOaLocation W30874906052 @default.
• W3087490605 hasConcept C126322002 @default.
• W3087490605 hasConcept C126838900 @default.
• W3087490605 hasConcept C141071460 @default.
• W3087490605 hasConcept C143753070 @default.
• W3087490605 hasConcept C2776468924 @default.
• W3087490605 hasConcept C2777397205 @default.
• W3087490605 hasConcept C2777714996 @default.
• W3087490605 hasConcept C2779537118 @default.
• W3087490605 hasConcept C2780886150 @default.
• W3087490605 hasConcept C2989005 @default.
• W3087490605 hasConcept C42219234 @default.
• W3087490605 hasConcept C534529494 @default.
• W3087490605 hasConcept C71924100 @default.
• W3087490605 hasConceptScore W3087490605C126322002 @default.
• W3087490605 hasConceptScore W3087490605C126838900 @default.
• W3087490605 hasConceptScore W3087490605C141071460 @default.
• W3087490605 hasConceptScore W3087490605C143753070 @default.
• W3087490605 hasConceptScore W3087490605C2776468924 @default.
• W3087490605 hasConceptScore W3087490605C2777397205 @default.
• W3087490605 hasConceptScore W3087490605C2777714996 @default.
• W3087490605 hasConceptScore W3087490605C2779537118 @default.
• W3087490605 hasConceptScore W3087490605C2780886150 @default.
• W3087490605 hasConceptScore W3087490605C2989005 @default.
• W3087490605 hasConceptScore W3087490605C42219234 @default.
• W3087490605 hasConceptScore W3087490605C534529494 @default.
• W3087490605 hasConceptScore W3087490605C71924100 @default.
• W3087490605 hasIssue "15" @default.
• W3087490605 hasLocation W30874906051 @default.
• W3087490605 hasLocation W30874906052 @default.
• W3087490605 hasLocation W30874906053 @default.
• W3087490605 hasOpenAccess W3087490605 @default.
• W3087490605 hasPrimaryLocation W30874906051 @default.
• W3087490605 hasRelatedWork W2068771676 @default.
• W3087490605 hasRelatedWork W2129363868 @default.
• W3087490605 hasRelatedWork W2136995523 @default.

• next