Matches in SemOpenAlex for { <https://semopenalex.org/work/W3087536635> ?p ?o ?g. }
- W3087536635 endingPage "111513" @default.
- W3087536635 startingPage "111513" @default.
- W3087536635 abstract "Infection associated with titanium based implants remains the most serious problem in implant surgery hence it is important to find optimal strategies to prevent infections. In the present study, we investigated the surface properties, antibacterial activity and biocompatibility of nanocomposite coatings based on an amorphous hydrocarbon (a-C:H) film containing copper nanoparticles (CuNPs) deposited on Ti discs via a gas aggregation cluster source. Three different Cu/a-C:H coatings with approximately the same amount of embedded CuNPs with and without barrier a-C:H layer were fabricated. The obtained results revealed that different structures of the produced coatings have significantly different release rates of Cu ions from the coatings into the aqueous media. This subsequently influences the antibacterial efficiency and osteoblast cell viability of the treated coatings. Coatings with the highest number of CuNPs resulted in excellent antibacterial activity exhibiting approximately 4 log reduction of E.coli and S.aureus after 24 h incubation. The cytotoxicity study revealed that after 7 day cell seeding, even the coating with the highest Cu at.% (4 at.%) showed a cell viability of ̴90%. Consequently, the coating, formed with a properly tailored number of CuNPs and a-C:H barrier thickness offer a strong antibacterial effect without any harm to osteoblast cells. • Role of Cu embedded a-C:H nano coating on Ti substrates have been investigated. • Coatings with different structure have different release rate of Cu ions • The produced coatings have greatly improved the antibacterial and biocompatible property of Ti substrates. • Surface topography, surface chemistry and controlled release of Cu 2+ are the contributing factors to cell interactions." @default.
- W3087536635 created "2020-09-25" @default.
- W3087536635 creator A5006793085 @default.
- W3087536635 creator A5024010999 @default.
- W3087536635 creator A5025389706 @default.
- W3087536635 creator A5029003003 @default.
- W3087536635 creator A5036549566 @default.
- W3087536635 creator A5038090967 @default.
- W3087536635 creator A5044658592 @default.
- W3087536635 creator A5045359292 @default.
- W3087536635 creator A5045863442 @default.
- W3087536635 creator A5051664834 @default.
- W3087536635 creator A5055533401 @default.
- W3087536635 creator A5060599083 @default.
- W3087536635 creator A5072197110 @default.
- W3087536635 creator A5073313322 @default.
- W3087536635 creator A5087422125 @default.
- W3087536635 date "2021-02-01" @default.
- W3087536635 modified "2023-10-03" @default.
- W3087536635 title "Biological activity and antimicrobial property of Cu/a-C:H nanocomposites and nanolayered coatings on titanium substrates" @default.
- W3087536635 cites W1750512125 @default.
- W3087536635 cites W1830530885 @default.
- W3087536635 cites W1899608324 @default.
- W3087536635 cites W1963975473 @default.
- W3087536635 cites W1972074710 @default.
- W3087536635 cites W1979201029 @default.
- W3087536635 cites W1988565234 @default.
- W3087536635 cites W1994625357 @default.
- W3087536635 cites W2000166788 @default.
- W3087536635 cites W2012596632 @default.
- W3087536635 cites W2022132714 @default.
- W3087536635 cites W2025022842 @default.
- W3087536635 cites W2025935616 @default.
- W3087536635 cites W2030497560 @default.
- W3087536635 cites W2032808656 @default.
- W3087536635 cites W2040014098 @default.
- W3087536635 cites W2043975509 @default.
- W3087536635 cites W2045564716 @default.
- W3087536635 cites W2049715149 @default.
- W3087536635 cites W2066620824 @default.
- W3087536635 cites W2080921228 @default.
- W3087536635 cites W2083569662 @default.
- W3087536635 cites W2109950553 @default.
- W3087536635 cites W2124837211 @default.
- W3087536635 cites W2137140957 @default.
- W3087536635 cites W2187790984 @default.
- W3087536635 cites W2263217363 @default.
- W3087536635 cites W2318867362 @default.
- W3087536635 cites W2335335535 @default.
- W3087536635 cites W2343340339 @default.
- W3087536635 cites W2408938440 @default.
- W3087536635 cites W2540704498 @default.
- W3087536635 cites W2564364768 @default.
- W3087536635 cites W2599518580 @default.
- W3087536635 cites W2699609419 @default.
- W3087536635 cites W2748215620 @default.
- W3087536635 cites W2794319682 @default.
- W3087536635 cites W2799786643 @default.
- W3087536635 cites W2883600490 @default.
- W3087536635 cites W2900960982 @default.
- W3087536635 cites W2911527623 @default.
- W3087536635 cites W2912738866 @default.
- W3087536635 cites W2922833665 @default.
- W3087536635 cites W2944713846 @default.
- W3087536635 cites W3023639309 @default.
- W3087536635 cites W4200434964 @default.
- W3087536635 doi "https://doi.org/10.1016/j.msec.2020.111513" @default.
- W3087536635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33321606" @default.
- W3087536635 hasPublicationYear "2021" @default.
- W3087536635 type Work @default.
- W3087536635 sameAs 3087536635 @default.
- W3087536635 citedByCount "15" @default.
- W3087536635 countsByYear W30875366352021 @default.
- W3087536635 countsByYear W30875366352022 @default.
- W3087536635 countsByYear W30875366352023 @default.
- W3087536635 crossrefType "journal-article" @default.
- W3087536635 hasAuthorship W3087536635A5006793085 @default.
- W3087536635 hasAuthorship W3087536635A5024010999 @default.
- W3087536635 hasAuthorship W3087536635A5025389706 @default.
- W3087536635 hasAuthorship W3087536635A5029003003 @default.
- W3087536635 hasAuthorship W3087536635A5036549566 @default.
- W3087536635 hasAuthorship W3087536635A5038090967 @default.
- W3087536635 hasAuthorship W3087536635A5044658592 @default.
- W3087536635 hasAuthorship W3087536635A5045359292 @default.
- W3087536635 hasAuthorship W3087536635A5045863442 @default.
- W3087536635 hasAuthorship W3087536635A5051664834 @default.
- W3087536635 hasAuthorship W3087536635A5055533401 @default.
- W3087536635 hasAuthorship W3087536635A5060599083 @default.
- W3087536635 hasAuthorship W3087536635A5072197110 @default.
- W3087536635 hasAuthorship W3087536635A5073313322 @default.
- W3087536635 hasAuthorship W3087536635A5087422125 @default.
- W3087536635 hasBestOaLocation W30875366351 @default.
- W3087536635 hasConcept C127413603 @default.
- W3087536635 hasConcept C171250308 @default.
- W3087536635 hasConcept C178790620 @default.
- W3087536635 hasConcept C185592680 @default.
- W3087536635 hasConcept C191897082 @default.
- W3087536635 hasConcept C192562407 @default.