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- W3087564462 abstract "Two synthetic approaches to enaminones fused to 1,4-benzothiazin-2-one moiety, which can be interesting in studies on biological activity, chemosensors, and fluorescence, were developed via the reaction of furan-2,3-diones or acylpyruvic acids in the presence of carbodiimides with o -aminothiophenols. The target enaminones were formed together with pharmaceutically interesting 2-hydroxy-2 H -1,4-benzothiazin-3(4 H )-ones. A selective synthetic approach to 2-hydroxy-2 H -1,4-benzothiazin-3(4 H )-ones was developed via the solvent-switchable reaction of furan-2,3-diones with o -aminothiophenol. Preliminary biological assays (antimicrobial, acute toxicity) of the new compounds were carried out." @default.
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- W3087564462 date "2020-09-21" @default.
- W3087564462 modified "2023-09-27" @default.
- W3087564462 title "Synthesis of 1,4-benzothiazinones from acylpyruvic acids or furan-2,3-diones and <i>o</i>-aminothiophenol" @default.
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- W3087564462 doi "https://doi.org/10.3762/bjoc.16.193" @default.
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