Matches in SemOpenAlex for { <https://semopenalex.org/work/W3087579231> ?p ?o ?g. }
- W3087579231 endingPage "2094" @default.
- W3087579231 startingPage "2085" @default.
- W3087579231 abstract "Basic and clinical research have demonstrated that osteoprotegerin (OPG) plays an important role in the development and progression of cardiovascular diseases. The aim of this study was to evaluate the association of four polymorphic sites (rs2073618, rs3134069, rs3134070, and rs3102735) of OPG gene with premature coronary artery disease (pCAD), and with cardiometabolic parameters. The polymorphisms were genotyped using 5' exonuclease TaqMan genotyping assays with real-time PCR in 1098 individuals with pCAD and 1041 healthy controls. rs2073618 polymorphism was associated with a high risk of developing pCAD according to different inheritance models: additive (p = 0.001; odds ratio [OR] = 1.283), dominant (p = 0.006; OR = 1.383), recessive (p = 0.011; OR = 1.423), and codominant 2 (p = 0.001; OR = 1.646). The four polymorphisms were associated with different cardiovascular risk factors in individuals with pCAD and controls. Our results suggest that OPG rs2073618 polymorphism is associated with an increased risk of pCAD. In addition, two haplotypes were associated with pCAD, one increasing the risk (CACT) and another one as protective (GACC)." @default.
- W3087579231 created "2020-09-25" @default.
- W3087579231 creator A5011487068 @default.
- W3087579231 creator A5042811425 @default.
- W3087579231 creator A5048739950 @default.
- W3087579231 creator A5058308594 @default.
- W3087579231 creator A5086772162 @default.
- W3087579231 creator A5088612223 @default.
- W3087579231 date "2020-11-01" @default.
- W3087579231 modified "2023-10-01" @default.
- W3087579231 title "Genetic Variants and Haplotypes in <i>OPG</i> Gene Are Associated with Premature Coronary Artery Disease and Traditional Cardiovascular Risk Factors in Mexican Population: The GEA Study" @default.
- W3087579231 cites W1970198745 @default.
- W3087579231 cites W1988051579 @default.
- W3087579231 cites W1992440806 @default.
- W3087579231 cites W2000647744 @default.
- W3087579231 cites W2005874745 @default.
- W3087579231 cites W2024444522 @default.
- W3087579231 cites W2046381913 @default.
- W3087579231 cites W2067921845 @default.
- W3087579231 cites W2069290111 @default.
- W3087579231 cites W2085627947 @default.
- W3087579231 cites W2085707502 @default.
- W3087579231 cites W2098909999 @default.
- W3087579231 cites W2112552033 @default.
- W3087579231 cites W2116818902 @default.
- W3087579231 cites W2120388900 @default.
- W3087579231 cites W2121120992 @default.
- W3087579231 cites W212908587 @default.
- W3087579231 cites W2153550523 @default.
- W3087579231 cites W2158670489 @default.
- W3087579231 cites W2159234056 @default.
- W3087579231 cites W2161677448 @default.
- W3087579231 cites W2167886526 @default.
- W3087579231 cites W2168154236 @default.
- W3087579231 cites W2190278821 @default.
- W3087579231 cites W2323940388 @default.
- W3087579231 cites W2324307101 @default.
- W3087579231 cites W2510135464 @default.
- W3087579231 cites W2512088551 @default.
- W3087579231 cites W2586285453 @default.
- W3087579231 cites W2601866644 @default.
- W3087579231 cites W2733706002 @default.
- W3087579231 cites W2770171834 @default.
- W3087579231 cites W2783584240 @default.
- W3087579231 cites W2788727968 @default.
- W3087579231 cites W2807169582 @default.
- W3087579231 cites W2809177481 @default.
- W3087579231 cites W2884694793 @default.
- W3087579231 cites W2895214253 @default.
- W3087579231 cites W2899536388 @default.
- W3087579231 cites W2901674887 @default.
- W3087579231 cites W2902822862 @default.
- W3087579231 cites W2910132592 @default.
- W3087579231 cites W2910899227 @default.
- W3087579231 cites W2912195140 @default.
- W3087579231 cites W2913942555 @default.
- W3087579231 cites W2921813286 @default.
- W3087579231 cites W2922369315 @default.
- W3087579231 cites W2922371507 @default.
- W3087579231 cites W2944904922 @default.
- W3087579231 cites W2947913028 @default.
- W3087579231 cites W2948140894 @default.
- W3087579231 cites W2950594647 @default.
- W3087579231 cites W2952292872 @default.
- W3087579231 cites W2957271693 @default.
- W3087579231 cites W2970599538 @default.
- W3087579231 cites W2985465480 @default.
- W3087579231 cites W3004337908 @default.
- W3087579231 cites W3007557663 @default.
- W3087579231 cites W2605686978 @default.
- W3087579231 doi "https://doi.org/10.1089/dna.2020.5949" @default.
- W3087579231 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7687050" @default.
- W3087579231 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32955941" @default.
- W3087579231 hasPublicationYear "2020" @default.
- W3087579231 type Work @default.
- W3087579231 sameAs 3087579231 @default.
- W3087579231 citedByCount "2" @default.
- W3087579231 countsByYear W30875792312022 @default.
- W3087579231 crossrefType "journal-article" @default.
- W3087579231 hasAuthorship W3087579231A5011487068 @default.
- W3087579231 hasAuthorship W3087579231A5042811425 @default.
- W3087579231 hasAuthorship W3087579231A5048739950 @default.
- W3087579231 hasAuthorship W3087579231A5058308594 @default.
- W3087579231 hasAuthorship W3087579231A5086772162 @default.
- W3087579231 hasAuthorship W3087579231A5088612223 @default.
- W3087579231 hasBestOaLocation W30875792312 @default.
- W3087579231 hasConcept C104317684 @default.
- W3087579231 hasConcept C126322002 @default.
- W3087579231 hasConcept C135763542 @default.
- W3087579231 hasConcept C153209595 @default.
- W3087579231 hasConcept C156957248 @default.
- W3087579231 hasConcept C197754878 @default.
- W3087579231 hasConcept C2778213512 @default.
- W3087579231 hasConcept C2908647359 @default.
- W3087579231 hasConcept C31467283 @default.
- W3087579231 hasConcept C54355233 @default.
- W3087579231 hasConcept C71924100 @default.
- W3087579231 hasConcept C86803240 @default.