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- W3087628372 endingPage "102074" @default.
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- W3087628372 abstract "Recent years have witnessed that silver nanoparticles have demonstrated an efficient and broad range of antimicrobial activity in proportion to other metal nanoparticles. Herein, we report the synthesis of biocompatible silver nanoparticles by using glycolic acid (GA-AgNPs) as a capping and reducing agent and their application as antimicrobial agents against skin cancer cells. GA-AgNPs were further characterized using UV–visible, transmission electron microscopy, fourier transform infrared spectroscopy, proton-nuclear magnetic resonance, dynamic light scattering and zeta potential. Further, in order to assess their antibacterial potential, the synthesized nanoparticles were tested against Gram-positive and Gram-negative bacterial strains. The results revealed that synthesized GA-AgNPs were very active against the tested Gram-negative as well as Gram-positive pathogens. Also, the ion release study was performed using inductively coupled plasma-mass spectrometry. Further, in order to check their biocompatibility, cytotoxicity studies of the AgNPs were performed against skin cell lines (HaCaT) and these were found to be relatively non-toxic. This study, therefore, opened a new pathway for further applications of GA-AgNPs in targeting skin infections and fighting multi drug resistance." @default.
- W3087628372 created "2020-09-25" @default.
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- W3087628372 date "2020-12-01" @default.
- W3087628372 modified "2023-10-17" @default.
- W3087628372 title "Glycolic acid functionalized silver nanoparticles: A novel approach towards generation of effective antibacterial agent against skin infections" @default.
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- W3087628372 doi "https://doi.org/10.1016/j.jddst.2020.102074" @default.
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