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• W3087757544 abstract "Left ventricular assist device (LVAD) implantation may be an attractive alternative therapeutic option for elderly patients with heart failure who are ineligible for heart transplantation. We aimed to describe the characteristics and outcomes of elderly patients (i.e. aged ≥ 70 years) receiving an LVAD. This observational study was conducted in 19 centres between 2006 and 2016. Patients were divided into two groups–younger (aged < 70 years) and elderly (aged ≥ 70 years), based on age at time of LVAD implantation. A total of 652 patients were included in the final analysis, and 74 patients (11.3%) were aged ≥ 70 years at the time of LVAD implantation (maximal age 77.6 years). The proportion of elderly patients receiving an LVAD each year was constant, with a median of 10.6% (interquartile range 8.0–15.4%) per year, and all were implanted as destination therapy. Elderly and younger patients had similar durations of hospitalization in intensive care units and total lengths of hospital stays. Both age groups experienced similar rates of LVAD-related complications (i.e. stroke, bleeding, driveline infection and LVAD exchange), and the occurrence of LVAD complications did not impact survival in the elderly group compared with the younger group. Lastly, when compared with younger patients implanted as destination therapy, the elderly group also exhibited similar mid-term survival. This work strongly suggests that selected elderly adults can be scheduled for LVAD implantation. L’implantation d’une assistance cardiaque de longue durée (LVAD) peut être une séduisante alternative thérapeutique pour les patients insuffisants cardiaques âgés non éligible à une transplantation cardiaque. Dans cette étude, nous décrivons les caractéristiques et résultats de l’implantation d’une assistance cardiaque mono-ventriculaire gauche chez des patients âgés de plus de 70 ans. Les patients implantés d’un LVAD dans 19 centres français entre 2006 et 2016 ont été inclus et divisés en deux groupes suivant l’âge à l’implantation (≥ 70 ou < 70 ans). Un total de 652 patients ont été inclus et 74 (11,3 %) étaient âgés de plus de 70 ans à l’implantation du LVAD (maximal à 77,6 ans). La proportion de patients ayant ≥ 70 ans implanté d’un LVAD est constante chaque année avec une médiane de 10,6 % (8,0–15,4 %). Les 74 patients ont tous été implantés en thérapie définitive. Les deux groupes ont une durée d’hospitalisation (en réanimation et totale) similaire et développent un pourcentage identique de complications en lien avec le LVAD (accidents ischémiques, saignement, infection de câble, changement de LVAD). Le survenue d’une complication n’impact pas la survie chez les patients ≥ 70 ans par rapport au groupe < 70 ans. Enfin, parmi le sous-groupe de patients implantés en thérapie définitive, les deux populations (≥ 0 ou < 70 ans) ont une survie identique. Ce travail suggère que des patients insuffisants cardiaques âgés de plus de 70 ans et bien sélectionnés peuvent être de bons candidats à l’implantation d’un LVAD." @default.
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• W3087757544 date "2020-11-01" @default.
• W3087757544 modified "2023-10-18" @default.
• W3087757544 title "Septuagenarian population has similar survival and outcomes to younger patients after left ventricular assist device implantation" @default.
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• W3087757544 doi "https://doi.org/10.1016/j.acvd.2020.05.018" @default.
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