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- W3087767184 abstract "Abstract Cationic amino acid transporter 1 (Cat-1 alias Slc7a1) is a Na + -independent carrier system involved in transport and absorption of the cationic amino acids lysine, arginine, histidine, and ornithine and has also been shown to be indispensable in a large variety of biological processes. Starting from isolated full-length zebrafish ( Danio rerio ) cDNA for slc7a1a , we performed comparative and phylogenetic sequence analysis, investigated the conservation of the gene during vertebrate evolution, and defined tissue expression during zebrafish development. Whole mount in situ hybridization first detected slc7a1a transcripts in somites, eyes, and brain at 14 h post-fertilization (hpf) with additional expression in the distal nephron at 24 hpf and in branchial arches at 3 days post-fertilization (dpf), with significant increase by 5 dpf. Taken together, the expression analysis of the zebrafish Cat-1 system gene slc7a1a suggests a functional role(s) during the early development of the central nervous system, muscle, gills, and kidney." @default.
- W3087767184 created "2020-10-01" @default.
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- W3087767184 creator A5085120136 @default.
- W3087767184 date "2020-09-27" @default.
- W3087767184 modified "2023-10-17" @default.
- W3087767184 title "Sequence analysis and spatiotemporal developmental distribution of the Cat-1-type transporter slc7a1a in zebrafish (Danio rerio)" @default.
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- W3087767184 doi "https://doi.org/10.1007/s10695-020-00873-x" @default.
- W3087767184 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7584565" @default.
- W3087767184 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32980952" @default.
- W3087767184 hasPublicationYear "2020" @default.
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