Matches in SemOpenAlex for { <https://semopenalex.org/work/W3087842220> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W3087842220 endingPage "476" @default.
- W3087842220 startingPage "469" @default.
- W3087842220 abstract "Purpose: The development biosensing technologies capable of delivering fast and reliable analysis is a growing trend in drug quality control. Considering the emerging use of plant-based polyphenol oxidases (PPO) as biological component of electrochemical biosensors, this work reports the first Solanum lycocarpum PPO biosensor and its use in the pharmaceutical analysis of paracetamol in tablet formulations. Methods: The biosensor was optimized regarding fruit maturation (immature and mature-ripe), vegetal extract volume to be used in biosensor construction as well as optimal pH of electrochemical cell fluid. Results: Results evidenced that the extract which rendered the biosensor with best analytical performance was from immature fruits, and the biosensor produced using 100 µL of crude plant extract promoted better faradaic signal gathering. Moreover, when neutral pH media was used in the electrochemical cell, the biosensor showcased best faradaic signal output from the used redox probe (catechol), suggesting thence that the method presents high sensibility for phenolic compounds detection. Furthermore, the biosensor was able to quantify paracetamol in a linear range from 50 to 300 μM, showcasing LoD and LoQ of 3 μM and 10 μM, respectively. Conclusion: after careful evaluation, this biosensor might be a low-cost alternative for conventional pharmaceutical quality control methods." @default.
- W3087842220 created "2020-10-01" @default.
- W3087842220 creator A5018307982 @default.
- W3087842220 creator A5044788796 @default.
- W3087842220 creator A5048694664 @default.
- W3087842220 creator A5058017484 @default.
- W3087842220 creator A5064334131 @default.
- W3087842220 date "2020-07-07" @default.
- W3087842220 modified "2023-09-25" @default.
- W3087842220 title "Development and Optimization of Solanum Lycocarpum Polyphenol Oxidase-Based Biosensor and Application towards Paracetamol Detection" @default.
- W3087842220 cites W1129547807 @default.
- W3087842220 cites W1554419469 @default.
- W3087842220 cites W1574022644 @default.
- W3087842220 cites W1982030382 @default.
- W3087842220 cites W1984774301 @default.
- W3087842220 cites W2023217866 @default.
- W3087842220 cites W2028377268 @default.
- W3087842220 cites W2060359219 @default.
- W3087842220 cites W2069899837 @default.
- W3087842220 cites W2080254464 @default.
- W3087842220 cites W2123589392 @default.
- W3087842220 cites W2128635872 @default.
- W3087842220 cites W2142507137 @default.
- W3087842220 cites W2329287980 @default.
- W3087842220 cites W2419031153 @default.
- W3087842220 cites W2591054856 @default.
- W3087842220 cites W2753258083 @default.
- W3087842220 cites W2795182277 @default.
- W3087842220 cites W2799293257 @default.
- W3087842220 cites W2799675529 @default.
- W3087842220 cites W2801933606 @default.
- W3087842220 cites W2895528221 @default.
- W3087842220 cites W2899081413 @default.
- W3087842220 cites W2916524482 @default.
- W3087842220 cites W2935027246 @default.
- W3087842220 cites W2946293350 @default.
- W3087842220 cites W2966245739 @default.
- W3087842220 doi "https://doi.org/10.34172/apb.2021.054" @default.
- W3087842220 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8421623" @default.
- W3087842220 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34513621" @default.
- W3087842220 hasPublicationYear "2020" @default.
- W3087842220 type Work @default.
- W3087842220 sameAs 3087842220 @default.
- W3087842220 citedByCount "3" @default.
- W3087842220 countsByYear W30878422202022 @default.
- W3087842220 countsByYear W30878422202023 @default.
- W3087842220 crossrefType "journal-article" @default.
- W3087842220 hasAuthorship W3087842220A5018307982 @default.
- W3087842220 hasAuthorship W3087842220A5044788796 @default.
- W3087842220 hasAuthorship W3087842220A5048694664 @default.
- W3087842220 hasAuthorship W3087842220A5058017484 @default.
- W3087842220 hasAuthorship W3087842220A5064334131 @default.
- W3087842220 hasBestOaLocation W30878422201 @default.
- W3087842220 hasConcept C10349863 @default.
- W3087842220 hasConcept C119128265 @default.
- W3087842220 hasConcept C160756335 @default.
- W3087842220 hasConcept C162008176 @default.
- W3087842220 hasConcept C171250308 @default.
- W3087842220 hasConcept C181199279 @default.
- W3087842220 hasConcept C185592680 @default.
- W3087842220 hasConcept C192562407 @default.
- W3087842220 hasConcept C2776338311 @default.
- W3087842220 hasConcept C2777713698 @default.
- W3087842220 hasConcept C43617362 @default.
- W3087842220 hasConcept C55493867 @default.
- W3087842220 hasConceptScore W3087842220C10349863 @default.
- W3087842220 hasConceptScore W3087842220C119128265 @default.
- W3087842220 hasConceptScore W3087842220C160756335 @default.
- W3087842220 hasConceptScore W3087842220C162008176 @default.
- W3087842220 hasConceptScore W3087842220C171250308 @default.
- W3087842220 hasConceptScore W3087842220C181199279 @default.
- W3087842220 hasConceptScore W3087842220C185592680 @default.
- W3087842220 hasConceptScore W3087842220C192562407 @default.
- W3087842220 hasConceptScore W3087842220C2776338311 @default.
- W3087842220 hasConceptScore W3087842220C2777713698 @default.
- W3087842220 hasConceptScore W3087842220C43617362 @default.
- W3087842220 hasConceptScore W3087842220C55493867 @default.
- W3087842220 hasIssue "3" @default.
- W3087842220 hasLocation W30878422201 @default.
- W3087842220 hasLocation W30878422202 @default.
- W3087842220 hasLocation W30878422203 @default.
- W3087842220 hasOpenAccess W3087842220 @default.
- W3087842220 hasPrimaryLocation W30878422201 @default.
- W3087842220 hasRelatedWork W2025270230 @default.
- W3087842220 hasRelatedWork W2026247530 @default.
- W3087842220 hasRelatedWork W2074215185 @default.
- W3087842220 hasRelatedWork W2087464329 @default.
- W3087842220 hasRelatedWork W2093898294 @default.
- W3087842220 hasRelatedWork W2746490423 @default.
- W3087842220 hasRelatedWork W2764102108 @default.
- W3087842220 hasRelatedWork W2943505799 @default.
- W3087842220 hasRelatedWork W2950001845 @default.
- W3087842220 hasRelatedWork W4298286752 @default.
- W3087842220 hasVolume "11" @default.
- W3087842220 isParatext "false" @default.
- W3087842220 isRetracted "false" @default.
- W3087842220 magId "3087842220" @default.
- W3087842220 workType "article" @default.