FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3087877652> ?p ?o ?g. }

• W3087877652 endingPage "4383.e7" @default.
• W3087877652 startingPage "4373" @default.
• W3087877652 abstract "Mammalian sleep expression and regulation have historically been thought to reflect the activity of neurons. Changes in other brain cells (glia) across the sleep-wake cycle and their role in sleep regulation are comparatively unexplored. We show that sleep and wakefulness are accompanied by state-dependent changes in astroglial activity. Using a miniature microscope in freely behaving mice and a two-photon microscope in head-fixed, unanesthetized mice, we show that astroglial calcium signals are highest in wake and lowest in sleep and are most pronounced in astroglial processes. We also find that astroglial calcium signals during non-rapid eye movement sleep change in proportion to sleep need. In contrast to neurons, astrocytes become less synchronized during non-rapid eye movement sleep after sleep deprivation at the network and single-cell level. Finally, we show that conditionally reducing intracellular calcium in astrocytes impairs the homeostatic response to sleep deprivation. Thus, astroglial calcium activity changes dynamically across vigilance states, is proportional to sleep need, and is a component of the sleep homeostat." @default.
• W3087877652 created "2020-10-01" @default.
• W3087877652 creator A5026195173 @default.
• W3087877652 creator A5026740619 @default.
• W3087877652 creator A5046150737 @default.
• W3087877652 creator A5061649703 @default.
• W3087877652 creator A5067318148 @default.
• W3087877652 creator A5083226472 @default.
• W3087877652 creator A5087875874 @default.
• W3087877652 date "2020-11-01" @default.
• W3087877652 modified "2023-10-17" @default.
• W3087877652 title "A Role for Astroglial Calcium in Mammalian Sleep and Sleep Regulation" @default.
• W3087877652 cites W1594747697 @default.
• W3087877652 cites W1933979928 @default.
• W3087877652 cites W1955954835 @default.
• W3087877652 cites W1967285334 @default.
• W3087877652 cites W1971974326 @default.
• W3087877652 cites W1977294596 @default.
• W3087877652 cites W1997680764 @default.
• W3087877652 cites W2008815148 @default.
• W3087877652 cites W2009991455 @default.
• W3087877652 cites W2043625816 @default.
• W3087877652 cites W2046964445 @default.
• W3087877652 cites W2048087130 @default.
• W3087877652 cites W2051320847 @default.
• W3087877652 cites W2063210874 @default.
• W3087877652 cites W2070865530 @default.
• W3087877652 cites W2076310752 @default.
• W3087877652 cites W2079574859 @default.
• W3087877652 cites W2080846359 @default.
• W3087877652 cites W2086238474 @default.
• W3087877652 cites W2098412291 @default.
• W3087877652 cites W2099540110 @default.
• W3087877652 cites W2103986640 @default.
• W3087877652 cites W2104662726 @default.
• W3087877652 cites W2112339527 @default.
• W3087877652 cites W2116308842 @default.
• W3087877652 cites W2120144854 @default.
• W3087877652 cites W2129250361 @default.
• W3087877652 cites W2135723200 @default.
• W3087877652 cites W2146678583 @default.
• W3087877652 cites W2147372806 @default.
• W3087877652 cites W2149790761 @default.
• W3087877652 cites W2157744021 @default.
• W3087877652 cites W2167279371 @default.
• W3087877652 cites W2260140125 @default.
• W3087877652 cites W2274452385 @default.
• W3087877652 cites W2331906705 @default.
• W3087877652 cites W2343186916 @default.
• W3087877652 cites W2411086663 @default.
• W3087877652 cites W2509318050 @default.
• W3087877652 cites W2580475180 @default.
• W3087877652 cites W2588320379 @default.
• W3087877652 cites W2604556368 @default.
• W3087877652 cites W2609025448 @default.
• W3087877652 cites W2619879339 @default.
• W3087877652 cites W2762639468 @default.
• W3087877652 cites W2765155499 @default.
• W3087877652 cites W2781911216 @default.
• W3087877652 cites W2782344173 @default.
• W3087877652 cites W2782839569 @default.
• W3087877652 cites W2785653274 @default.
• W3087877652 cites W2787267929 @default.
• W3087877652 cites W2787419526 @default.
• W3087877652 cites W2802988332 @default.
• W3087877652 cites W2804381908 @default.
• W3087877652 cites W2889292974 @default.
• W3087877652 cites W2891879612 @default.
• W3087877652 cites W2914675220 @default.
• W3087877652 cites W2950418175 @default.
• W3087877652 cites W2951203650 @default.
• W3087877652 cites W2975543744 @default.
• W3087877652 cites W2979887891 @default.
• W3087877652 cites W3038311941 @default.
• W3087877652 doi "https://doi.org/10.1016/j.cub.2020.08.052" @default.
• W3087877652 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7919541" @default.
• W3087877652 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32976809" @default.
• W3087877652 hasPublicationYear "2020" @default.
• W3087877652 type Work @default.
• W3087877652 sameAs 3087877652 @default.
• W3087877652 citedByCount "76" @default.
• W3087877652 countsByYear W30878776522020 @default.
• W3087877652 countsByYear W30878776522021 @default.
• W3087877652 countsByYear W30878776522022 @default.
• W3087877652 countsByYear W30878776522023 @default.
• W3087877652 crossrefType "journal-article" @default.
• W3087877652 hasAuthorship W3087877652A5026195173 @default.
• W3087877652 hasAuthorship W3087877652A5026740619 @default.
• W3087877652 hasAuthorship W3087877652A5046150737 @default.
• W3087877652 hasAuthorship W3087877652A5061649703 @default.
• W3087877652 hasAuthorship W3087877652A5067318148 @default.
• W3087877652 hasAuthorship W3087877652A5083226472 @default.
• W3087877652 hasAuthorship W3087877652A5087875874 @default.
• W3087877652 hasBestOaLocation W30878776521 @default.
• W3087877652 hasConcept C111919701 @default.
• W3087877652 hasConcept C126322002 @default.
• W3087877652 hasConcept C169760540 @default.
• W3087877652 hasConcept C2775841894 @default.

• next