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• W3087955274 abstract "Abstract Three-dimensional (3D) conformation of the chromatin is crucial to stringently regulate gene expression patterns and DNA replication in a cell-type specific manner. HiC is a key technique for measuring 3D chromatin interactions genome wide. Estimating and predicting the resolution of a library is an essential step in any HiC experimental design. Here, we present the mathematical concepts to estimate the resolution of a library and predict whether deeper sequencing would enhance the resolution. We have developed HiCRes, a docker pipeline, by applying these concepts to human and mouse HiC libraries." @default.
• W3087955274 created "2020-10-01" @default.
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• W3087955274 date "2020-09-22" @default.
• W3087955274 modified "2023-09-27" @default.
• W3087955274 title "HiCRes: a computational method to estimate and predict the resolution of HiC libraries" @default.
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• W3087955274 doi "https://doi.org/10.1101/2020.09.22.307967" @default.
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