FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3088024011> ?p ?o ?g. }

• W3088024011 endingPage "74" @default.
• W3088024011 startingPage "1" @default.
• W3088024011 abstract "Alcoholic beverages are socially accepted around the world and consumed mostly to socialize, celebrate, and relax. The pleasant effects of alcohol are attributed to (i) an increase in GABA ergic (inhibitory signals), OP ergic , and 5HT ergic (euphoric effects) neuronal activities and (ii) a decrease in DA ergic (“want” signal or craving), Glu ergic (excitatory signals), and NE ergic (stress signals) neuronal and the HPA axis (stress hormones) activities. If alcohol drinking continues, the receptors are sensitized, resulting in the development of tolerance when alcohol drinking must be increased to achieve the desired effects. In genetically/environmentally predisposed subjects, chronic alcohol drinking results in the development of addiction, characterized by a condition when alcohol caseation results in a rapid onset of withdrawal symptoms including, but not limited to, alcohol craving and moderate to severe discomfort. Because pharmacotherapy alone or in combination with behavioral approaches are only modestly effective in treating alcoholism symptoms, there is an urgent need for the development of effective and safe therapies. At present, a lack of clear understanding of the mechanisms underlying addiction hinders possible development of new treatment strategies. Therefore, this chapter aims to discuss the mechanisms underlying (i) the euphoric, relaxing, and adverse effects of alcohol drinking and (ii) addiction and the withdrawal symptoms." @default.
• W3088024011 created "2020-10-01" @default.
• W3088024011 creator A5059683938 @default.
• W3088024011 date "2021-01-01" @default.
• W3088024011 modified "2023-09-25" @default.
• W3088024011 title "Journey from responsible alcohol drinking to alcoholism" @default.
• W3088024011 cites W1207301358 @default.
• W3088024011 cites W134924606 @default.
• W3088024011 cites W1501723147 @default.
• W3088024011 cites W1504992746 @default.
• W3088024011 cites W1505495051 @default.
• W3088024011 cites W1510847502 @default.
• W3088024011 cites W1524203275 @default.
• W3088024011 cites W1535774104 @default.
• W3088024011 cites W1538418689 @default.
• W3088024011 cites W1543871407 @default.
• W3088024011 cites W1548679143 @default.
• W3088024011 cites W1549086489 @default.
• W3088024011 cites W1551663317 @default.
• W3088024011 cites W1562441344 @default.
• W3088024011 cites W1568198343 @default.
• W3088024011 cites W1576438053 @default.
• W3088024011 cites W1578292768 @default.
• W3088024011 cites W1580968401 @default.
• W3088024011 cites W158293295 @default.
• W3088024011 cites W1584138169 @default.
• W3088024011 cites W1594412667 @default.
• W3088024011 cites W1598454484 @default.
• W3088024011 cites W1601463464 @default.
• W3088024011 cites W1607380607 @default.
• W3088024011 cites W1609084115 @default.
• W3088024011 cites W1668093331 @default.
• W3088024011 cites W1701778517 @default.
• W3088024011 cites W1754082247 @default.
• W3088024011 cites W1761714741 @default.
• W3088024011 cites W1771503649 @default.
• W3088024011 cites W1797972710 @default.
• W3088024011 cites W1852077611 @default.
• W3088024011 cites W1870304014 @default.
• W3088024011 cites W1924585284 @default.
• W3088024011 cites W1925492557 @default.
• W3088024011 cites W1937687163 @default.
• W3088024011 cites W1951822496 @default.
• W3088024011 cites W1959149129 @default.
• W3088024011 cites W1964202448 @default.
• W3088024011 cites W1964739293 @default.
• W3088024011 cites W1965138184 @default.
• W3088024011 cites W1966584769 @default.
• W3088024011 cites W1967051580 @default.
• W3088024011 cites W1969590010 @default.
• W3088024011 cites W1969826754 @default.
• W3088024011 cites W1970226919 @default.
• W3088024011 cites W1971931358 @default.
• W3088024011 cites W1972183007 @default.
• W3088024011 cites W1972886570 @default.
• W3088024011 cites W1973461902 @default.
• W3088024011 cites W1974322969 @default.
• W3088024011 cites W1974466912 @default.
• W3088024011 cites W1974720828 @default.
• W3088024011 cites W1974968077 @default.
• W3088024011 cites W1975211606 @default.
• W3088024011 cites W1975670650 @default.
• W3088024011 cites W1975915682 @default.
• W3088024011 cites W1976551644 @default.
• W3088024011 cites W1976637929 @default.
• W3088024011 cites W1976681051 @default.
• W3088024011 cites W1976974906 @default.
• W3088024011 cites W1978196348 @default.
• W3088024011 cites W1978715208 @default.
• W3088024011 cites W1978836458 @default.
• W3088024011 cites W1979301735 @default.
• W3088024011 cites W1979640215 @default.
• W3088024011 cites W1980470416 @default.
• W3088024011 cites W1980471589 @default.
• W3088024011 cites W1980478962 @default.
• W3088024011 cites W1980571433 @default.
• W3088024011 cites W1980819328 @default.
• W3088024011 cites W1980844720 @default.
• W3088024011 cites W1981020370 @default.
• W3088024011 cites W1981085858 @default.
• W3088024011 cites W1983721111 @default.
• W3088024011 cites W1985244817 @default.
• W3088024011 cites W1985484802 @default.
• W3088024011 cites W1985705847 @default.
• W3088024011 cites W1986042731 @default.
• W3088024011 cites W1986447164 @default.
• W3088024011 cites W1986634200 @default.
• W3088024011 cites W1989271036 @default.
• W3088024011 cites W1989924524 @default.
• W3088024011 cites W1990611105 @default.
• W3088024011 cites W1991350649 @default.
• W3088024011 cites W1991731575 @default.
• W3088024011 cites W1993186640 @default.
• W3088024011 cites W1994576679 @default.
• W3088024011 cites W1994662713 @default.
• W3088024011 cites W1995424623 @default.
• W3088024011 cites W1996284892 @default.
• W3088024011 cites W2000607451 @default.

• next