Matches in SemOpenAlex for { <https://semopenalex.org/work/W3088034240> ?p ?o ?g. }
- W3088034240 endingPage "40" @default.
- W3088034240 startingPage "40" @default.
- W3088034240 abstract "Purpose: The purpose of this study was to investigate the relationship between circadian rhythm and intraocular pressure (IOP), and to explore whether electrical stimulation of cervical sympathetic ganglia (SCG) can regulate IOP via neurotransmitter distribution around the Schlemm's canal (SC) in rats. Methods: Sprague Dawley rats were housed under normal (N-normal), constant dark (N-dark), and constant light (N-light) rhythms (n = 6 per group). Electrical stimulation (intermittent wave [20 hertz {Hz}, 2 mA, 10 minutes]) was used to stimulate the SCG. Atropine sulfate eye gel was applied three times a day. DiI was injected into the SCG and anterior chamber. The cross-sectional area and circumference of SC were evaluated using hematoxylin-eosin staining. Immunofluorescence staining was used to evaluate dopamine-β-hydroxylase (DβH) expression in SC endothelial (SCE) cells. Results: N-Dark increased the IOP, decreased the cross-sectional area of SC, and increased DβH levels in SCE cells. Nerve projection between SC and SCG was detected, and electrical stimulation of SCG upregulated DβH expression in SCE cells. Under normal and constant light rhythms, electrical stimulation of SCG increased DβH and decreased the cross-sectional area and circumference of SC, while simultaneously increasing IOP and decreasing IOP fluctuations. After paralyzing the ciliary muscles, electrical stimulation of SCG decreased the cross-sectional area and circumference of SC under normal and constant light rhythms. Conclusions: N-Dark increased DβH in SCE cells, reduced the cross-sectional area of SC, and increased IOP. Under the normal and light rhythms, electrical stimulation of SCG increased DβH in SCE cells, reduced the cross-sectional area and circumference of SC, and in turn elevated IOP and decreased IOP fluctuations." @default.
- W3088034240 created "2020-10-01" @default.
- W3088034240 creator A5007578231 @default.
- W3088034240 creator A5010483409 @default.
- W3088034240 creator A5045914285 @default.
- W3088034240 creator A5050810233 @default.
- W3088034240 creator A5052077400 @default.
- W3088034240 creator A5056165952 @default.
- W3088034240 creator A5069143961 @default.
- W3088034240 creator A5069849278 @default.
- W3088034240 creator A5079906197 @default.
- W3088034240 date "2020-09-25" @default.
- W3088034240 modified "2023-10-04" @default.
- W3088034240 title "Effect of Electrical Stimulation of Cervical Sympathetic Ganglia on Intraocular Pressure Regulation According to Different Circadian Rhythms in Rats" @default.
- W3088034240 cites W1487053415 @default.
- W3088034240 cites W1824385193 @default.
- W3088034240 cites W1967208921 @default.
- W3088034240 cites W1969792498 @default.
- W3088034240 cites W1975068023 @default.
- W3088034240 cites W1980103871 @default.
- W3088034240 cites W1986761270 @default.
- W3088034240 cites W1994480994 @default.
- W3088034240 cites W2004810631 @default.
- W3088034240 cites W2023681120 @default.
- W3088034240 cites W2024249263 @default.
- W3088034240 cites W2046284962 @default.
- W3088034240 cites W2052911528 @default.
- W3088034240 cites W2067861040 @default.
- W3088034240 cites W2072057534 @default.
- W3088034240 cites W2078531740 @default.
- W3088034240 cites W2088035252 @default.
- W3088034240 cites W2107467757 @default.
- W3088034240 cites W2119054068 @default.
- W3088034240 cites W2119085011 @default.
- W3088034240 cites W2139676825 @default.
- W3088034240 cites W2141410612 @default.
- W3088034240 cites W2143967065 @default.
- W3088034240 cites W2144132437 @default.
- W3088034240 cites W2147093603 @default.
- W3088034240 cites W2168563911 @default.
- W3088034240 cites W2171679548 @default.
- W3088034240 cites W2220700528 @default.
- W3088034240 cites W2227291836 @default.
- W3088034240 cites W2277414475 @default.
- W3088034240 cites W2293543207 @default.
- W3088034240 cites W2394491350 @default.
- W3088034240 cites W2405258106 @default.
- W3088034240 cites W2496845339 @default.
- W3088034240 cites W2742047599 @default.
- W3088034240 cites W2766613771 @default.
- W3088034240 cites W2793080127 @default.
- W3088034240 cites W2839656001 @default.
- W3088034240 cites W2884290695 @default.
- W3088034240 cites W2889167689 @default.
- W3088034240 cites W2929016943 @default.
- W3088034240 cites W2947601007 @default.
- W3088034240 cites W4206485229 @default.
- W3088034240 cites W4229990889 @default.
- W3088034240 cites W4235019003 @default.
- W3088034240 cites W4237700722 @default.
- W3088034240 cites W4285698150 @default.
- W3088034240 cites W77698783 @default.
- W3088034240 doi "https://doi.org/10.1167/iovs.61.11.40" @default.
- W3088034240 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7521184" @default.
- W3088034240 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32976562" @default.
- W3088034240 hasPublicationYear "2020" @default.
- W3088034240 type Work @default.
- W3088034240 sameAs 3088034240 @default.
- W3088034240 citedByCount "5" @default.
- W3088034240 countsByYear W30880342402021 @default.
- W3088034240 countsByYear W30880342402022 @default.
- W3088034240 countsByYear W30880342402023 @default.
- W3088034240 crossrefType "journal-article" @default.
- W3088034240 hasAuthorship W3088034240A5007578231 @default.
- W3088034240 hasAuthorship W3088034240A5010483409 @default.
- W3088034240 hasAuthorship W3088034240A5045914285 @default.
- W3088034240 hasAuthorship W3088034240A5050810233 @default.
- W3088034240 hasAuthorship W3088034240A5052077400 @default.
- W3088034240 hasAuthorship W3088034240A5056165952 @default.
- W3088034240 hasAuthorship W3088034240A5069143961 @default.
- W3088034240 hasAuthorship W3088034240A5069849278 @default.
- W3088034240 hasAuthorship W3088034240A5079906197 @default.
- W3088034240 hasBestOaLocation W30880342401 @default.
- W3088034240 hasConcept C118487528 @default.
- W3088034240 hasConcept C121446783 @default.
- W3088034240 hasConcept C126322002 @default.
- W3088034240 hasConcept C134018914 @default.
- W3088034240 hasConcept C185592680 @default.
- W3088034240 hasConcept C24998067 @default.
- W3088034240 hasConcept C2778993773 @default.
- W3088034240 hasConcept C2781092963 @default.
- W3088034240 hasConcept C71924100 @default.
- W3088034240 hasConceptScore W3088034240C118487528 @default.
- W3088034240 hasConceptScore W3088034240C121446783 @default.
- W3088034240 hasConceptScore W3088034240C126322002 @default.
- W3088034240 hasConceptScore W3088034240C134018914 @default.
- W3088034240 hasConceptScore W3088034240C185592680 @default.
- W3088034240 hasConceptScore W3088034240C24998067 @default.