Matches in SemOpenAlex for { <https://semopenalex.org/work/W3088045208> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W3088045208 abstract "Abstract Increased accumulation of transcribed protein from damaged DNA and the decreased ability to repair DNA lead to many neurodegenerative diseases that lack effective therapies. Gene delivery is a new approach that transfers genetic material into the host cells to correct the damaged DNA and provide cells with new functions. Although, lentiviral/retroviral vectors are currently the most popular, the choice of a gene transfer factor depends on the disease. Besides these, the three general gene-editing tools such as zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats (CRISPR) are used in gene editing and among them, CRISPR is a revolution. Gene delivery can be used to modify different types of cells, but most of the cells that often used in neurodegeneration treatment are neural stem cells (NSCs), mesenchymal stem cells (MSCs), embryonic stem cells (ESCs), and induced progenitor stem cells (iPSCs). Among them, iPSCs have no ethical concerns and hold humongous potential." @default.
- W3088045208 created "2020-10-01" @default.
- W3088045208 creator A5007713883 @default.
- W3088045208 creator A5030089619 @default.
- W3088045208 creator A5033059380 @default.
- W3088045208 date "2020-01-01" @default.
- W3088045208 modified "2023-09-25" @default.
- W3088045208 title "Nanotechnology in gene delivery for neural regenerative medicine" @default.
- W3088045208 doi "https://doi.org/10.1016/b978-0-12-820223-4.00005-x" @default.
- W3088045208 hasPublicationYear "2020" @default.
- W3088045208 type Work @default.
- W3088045208 sameAs 3088045208 @default.
- W3088045208 citedByCount "0" @default.
- W3088045208 crossrefType "book-chapter" @default.
- W3088045208 hasAuthorship W3088045208A5007713883 @default.
- W3088045208 hasAuthorship W3088045208A5030089619 @default.
- W3088045208 hasAuthorship W3088045208A5033059380 @default.
- W3088045208 hasConcept C104317684 @default.
- W3088045208 hasConcept C107459253 @default.
- W3088045208 hasConcept C10854531 @default.
- W3088045208 hasConcept C111599444 @default.
- W3088045208 hasConcept C135983454 @default.
- W3088045208 hasConcept C136834591 @default.
- W3088045208 hasConcept C144501496 @default.
- W3088045208 hasConcept C145103041 @default.
- W3088045208 hasConcept C198826908 @default.
- W3088045208 hasConcept C28328180 @default.
- W3088045208 hasConcept C31909778 @default.
- W3088045208 hasConcept C32470452 @default.
- W3088045208 hasConcept C35802184 @default.
- W3088045208 hasConcept C40767141 @default.
- W3088045208 hasConcept C54355233 @default.
- W3088045208 hasConcept C70721500 @default.
- W3088045208 hasConcept C86803240 @default.
- W3088045208 hasConcept C95444343 @default.
- W3088045208 hasConcept C98108389 @default.
- W3088045208 hasConceptScore W3088045208C104317684 @default.
- W3088045208 hasConceptScore W3088045208C107459253 @default.
- W3088045208 hasConceptScore W3088045208C10854531 @default.
- W3088045208 hasConceptScore W3088045208C111599444 @default.
- W3088045208 hasConceptScore W3088045208C135983454 @default.
- W3088045208 hasConceptScore W3088045208C136834591 @default.
- W3088045208 hasConceptScore W3088045208C144501496 @default.
- W3088045208 hasConceptScore W3088045208C145103041 @default.
- W3088045208 hasConceptScore W3088045208C198826908 @default.
- W3088045208 hasConceptScore W3088045208C28328180 @default.
- W3088045208 hasConceptScore W3088045208C31909778 @default.
- W3088045208 hasConceptScore W3088045208C32470452 @default.
- W3088045208 hasConceptScore W3088045208C35802184 @default.
- W3088045208 hasConceptScore W3088045208C40767141 @default.
- W3088045208 hasConceptScore W3088045208C54355233 @default.
- W3088045208 hasConceptScore W3088045208C70721500 @default.
- W3088045208 hasConceptScore W3088045208C86803240 @default.
- W3088045208 hasConceptScore W3088045208C95444343 @default.
- W3088045208 hasConceptScore W3088045208C98108389 @default.
- W3088045208 hasLocation W30880452081 @default.
- W3088045208 hasOpenAccess W3088045208 @default.
- W3088045208 hasPrimaryLocation W30880452081 @default.
- W3088045208 hasRelatedWork W10791717 @default.
- W3088045208 hasRelatedWork W12192062 @default.
- W3088045208 hasRelatedWork W13139448 @default.
- W3088045208 hasRelatedWork W15544460 @default.
- W3088045208 hasRelatedWork W20456437 @default.
- W3088045208 hasRelatedWork W28767225 @default.
- W3088045208 hasRelatedWork W30659687 @default.
- W3088045208 hasRelatedWork W36188615 @default.
- W3088045208 hasRelatedWork W40581079 @default.
- W3088045208 hasRelatedWork W4238137 @default.
- W3088045208 isParatext "false" @default.
- W3088045208 isRetracted "false" @default.
- W3088045208 magId "3088045208" @default.
- W3088045208 workType "book-chapter" @default.