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- W3088051915 abstract "A new fluorescent chemosensor comprised of cucurbit[8]uril (Q[8]) and acridine hydrochloride (AC) has been designed and utilized for the recognition of amino acids. The AC was encapsulated by the Q[8] cavity and formed a 1:2 host-guest inclusion complex both in solution (aqueous) and in the solid-state. Whilst free AC is known to be strongly fluorescent, this strong fluorescence was quenched in the inclusion complex Q [8]-AC. This non-fluorescent complex Q[8]-AC was capable of serving as a fluorescence “off-on” probe, and was able to recognize either L-Phe or L-Trp via the competitive interaction between L-Phe or L-Trp. Moreover, the pH responsive nature of the probe allowed for the detection of basic amino acids, namely L-Arg, L-His, or L-Lys). As a result, a fluorescence method for the detection of five amino acids using a single system has been developed." @default.
- W3088051915 created "2020-10-01" @default.
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- W3088051915 date "2020-10-01" @default.
- W3088051915 modified "2023-10-14" @default.
- W3088051915 title "Amino acid recognition by a fluorescent chemosensor based on cucurbit[8]uril and acridine hydrochloride" @default.
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- W3088051915 doi "https://doi.org/10.1016/j.aca.2020.09.028" @default.
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