FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3088070633> ?p ?o ?g. }

• W3088070633 abstract "Melasma is a commonly acquired disorder of hyperpigmentation that often poses a therapeutic challenge for dermatologists. Recently, cysteamine cream has shown promising results compared to placebo. This study aims to determine the efficacy of cysteamine cream compared to hydroquinone cream in the treatment of melasma.A randomised, double-blinded, single-centre trial was conducted in Victoria, Australia. 20 recruited participants were given either cysteamine cream or hydroquinone cream for 16 weeks. The primary outcome measure was a change in the modified Melasma Area and Severity Index (mMASI). Quality of life at baseline and week 16 as well as standard digital photography at each follow-up visit was assessed as secondary outcome measures.At week 16, 14 participants completed the study with 5 participants in the cysteamine group and 9 patients in the hydroquinone group. In the intention to treat analysis, there was a 1.52 ± 0.69 (21.3%) reduction in mMASI for the cysteamine group and a 2.96 ± 1.15 (32%) reduction in the hydroquinone group. The difference between groups was not statistically significant (P = 0.3). Hydroquinone cream was generally better tolerated that cysteamine cream.Our study suggests that topical cysteamine may have comparable efficacy to topical hydroquinone. Cysteamine thus provides a possible alternative to patients and clinicians who wish to avoid or rotate off topical hydroquinone. While side effects were more common for participants using cysteamine compared with hydroquinone, these were mild and reversible. Larger studies comparing cysteamine and hydroquinone are required to support these findings." @default.
• W3088070633 created "2020-10-01" @default.
• W3088070633 creator A5009252575 @default.
• W3088070633 creator A5040996289 @default.
• W3088070633 creator A5054169218 @default.
• W3088070633 creator A5058586032 @default.
• W3088070633 creator A5065953614 @default.
• W3088070633 creator A5070832856 @default.
• W3088070633 creator A5080338163 @default.
• W3088070633 creator A5084151331 @default.
• W3088070633 creator A5086633481 @default.
• W3088070633 date "2020-09-27" @default.
• W3088070633 modified "2023-09-27" @default.
• W3088070633 title "Evaluation of the efficacy of cysteamine cream compared to hydroquinone in the treatment of melasma: A randomised, double‐blinded trial" @default.
• W3088070633 cites W1550963943 @default.
• W3088070633 cites W1689271154 @default.
• W3088070633 cites W1981452680 @default.
• W3088070633 cites W1997508994 @default.
• W3088070633 cites W2054000681 @default.
• W3088070633 cites W2077612459 @default.
• W3088070633 cites W2106803637 @default.
• W3088070633 cites W2149456909 @default.
• W3088070633 cites W2159446813 @default.
• W3088070633 cites W2345462183 @default.
• W3088070633 cites W2732348884 @default.
• W3088070633 cites W2900919730 @default.
• W3088070633 cites W2980136438 @default.
• W3088070633 cites W2994476652 @default.
• W3088070633 doi "https://doi.org/10.1111/ajd.13432" @default.
• W3088070633 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32981068" @default.
• W3088070633 hasPublicationYear "2020" @default.
• W3088070633 type Work @default.
• W3088070633 sameAs 3088070633 @default.
• W3088070633 citedByCount "13" @default.
• W3088070633 countsByYear W30880706332020 @default.
• W3088070633 countsByYear W30880706332021 @default.
• W3088070633 countsByYear W30880706332022 @default.
• W3088070633 countsByYear W30880706332023 @default.
• W3088070633 crossrefType "journal-article" @default.
• W3088070633 hasAuthorship W3088070633A5009252575 @default.
• W3088070633 hasAuthorship W3088070633A5040996289 @default.
• W3088070633 hasAuthorship W3088070633A5054169218 @default.
• W3088070633 hasAuthorship W3088070633A5058586032 @default.
• W3088070633 hasAuthorship W3088070633A5065953614 @default.
• W3088070633 hasAuthorship W3088070633A5070832856 @default.
• W3088070633 hasAuthorship W3088070633A5080338163 @default.
• W3088070633 hasAuthorship W3088070633A5084151331 @default.
• W3088070633 hasAuthorship W3088070633A5086633481 @default.
• W3088070633 hasConcept C126322002 @default.
• W3088070633 hasConcept C141071460 @default.
• W3088070633 hasConcept C142724271 @default.
• W3088070633 hasConcept C16005928 @default.
• W3088070633 hasConcept C168563851 @default.
• W3088070633 hasConcept C178790620 @default.
• W3088070633 hasConcept C185592680 @default.
• W3088070633 hasConcept C197934379 @default.
• W3088070633 hasConcept C204243189 @default.
• W3088070633 hasConcept C204787440 @default.
• W3088070633 hasConcept C27081682 @default.
• W3088070633 hasConcept C2776609658 @default.
• W3088070633 hasConcept C2776677263 @default.
• W3088070633 hasConcept C2776728111 @default.
• W3088070633 hasConcept C2777550763 @default.
• W3088070633 hasConcept C2778375690 @default.
• W3088070633 hasConcept C71924100 @default.
• W3088070633 hasConcept C98274493 @default.
• W3088070633 hasConceptScore W3088070633C126322002 @default.
• W3088070633 hasConceptScore W3088070633C141071460 @default.
• W3088070633 hasConceptScore W3088070633C142724271 @default.
• W3088070633 hasConceptScore W3088070633C16005928 @default.
• W3088070633 hasConceptScore W3088070633C168563851 @default.
• W3088070633 hasConceptScore W3088070633C178790620 @default.
• W3088070633 hasConceptScore W3088070633C185592680 @default.
• W3088070633 hasConceptScore W3088070633C197934379 @default.
• W3088070633 hasConceptScore W3088070633C204243189 @default.
• W3088070633 hasConceptScore W3088070633C204787440 @default.
• W3088070633 hasConceptScore W3088070633C27081682 @default.
• W3088070633 hasConceptScore W3088070633C2776609658 @default.
• W3088070633 hasConceptScore W3088070633C2776677263 @default.
• W3088070633 hasConceptScore W3088070633C2776728111 @default.
• W3088070633 hasConceptScore W3088070633C2777550763 @default.
• W3088070633 hasConceptScore W3088070633C2778375690 @default.
• W3088070633 hasConceptScore W3088070633C71924100 @default.
• W3088070633 hasConceptScore W3088070633C98274493 @default.
• W3088070633 hasIssue "1" @default.
• W3088070633 hasLocation W30880706331 @default.
• W3088070633 hasLocation W30880706332 @default.
• W3088070633 hasOpenAccess W3088070633 @default.
• W3088070633 hasPrimaryLocation W30880706331 @default.
• W3088070633 hasRelatedWork W159013847 @default.
• W3088070633 hasRelatedWork W1953070490 @default.
• W3088070633 hasRelatedWork W1964551359 @default.
• W3088070633 hasRelatedWork W2016165863 @default.
• W3088070633 hasRelatedWork W2033930419 @default.
• W3088070633 hasRelatedWork W2162913078 @default.
• W3088070633 hasRelatedWork W3088070633 @default.
• W3088070633 hasRelatedWork W3094343838 @default.
• W3088070633 hasRelatedWork W3180660927 @default.
• W3088070633 hasRelatedWork W4200587622 @default.
• W3088070633 hasVolume "62" @default.

• next